Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.D., University of Virginia 1985
• 

  Previous Appointments & Affiliations

  • Instructor in the Department of Orthopaedic Surgery, Orthopaedics, Orthopaedics 2017
• Research
• 

  Selected Grants

  • Biomechanical Sensors Vs Clinical Estimation for Gait Evaluation awarded by BioMech Holdings, LLC 2019 - 2020
  • Fresh Tissue Lab Agreement awarded by Medical Device Business Services, Inc. 2018
• 

  External Relationships

  • Biomech Holding LLC
  • Depuy Synthes
  • Moximed Inc.
  • The Hip Society
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Hernandez, Nicholas M., Zoe W. Hinton, Christine J. Wu, Samuel S. Wellman, William A. Jiranek, and Thorsten M. Seyler. “Varus-Valgus Constrained Implants in Revision Total Knee Arthroplasty: Mean Clinical Follow-Up of Six Years.” J Arthroplasty 36, no. 7S (July 2021): S303–7. https://doi.org/10.1016/j.arth.2020.12.017.
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    • Kannan, Arun, Peter L. Lewis, Chelsea Dyer, William A. Jiranek, and Stephen McMahon. “Do Fixed or Mobile Bearing Implants Have Better Survivorship in Medial Unicompartmental Knee Arthroplasty? A Study From the Australian Orthopaedic Association National Joint Replacement Registry.” Clin Orthop Relat Res 479, no. 7 (July 1, 2021): 1548–58. https://doi.org/10.1097/CORR.0000000000001698.
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    • Swiecicki, Albert, Nianyi Li, Jonathan O’Donnell, Nicholas Said, Jichen Yang, Richard C. Mather, William A. Jiranek, and Maciej A. Mazurowski. “Deep learning-based algorithm for assessment of knee osteoarthritis severity in radiographs matches performance of radiologists.” Comput Biol Med 133 (June 2021): 104334. https://doi.org/10.1016/j.compbiomed.2021.104334.
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    • Nwankwo, Vesta C., William A. Jiranek, Cynthia L. Green, Kelli D. Allen, Steven Z. George, and Janet Prvu Bettger. “Resilience and pain catastrophizing among patients with total knee arthroplasty: a cohort study to examine psychological constructs as predictors of post-operative outcomes.” Health Qual Life Outcomes 19, no. 1 (May 1, 2021): 136. https://doi.org/10.1186/s12955-021-01772-2.
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    • Steele, John R., Sean P. Ryan, William A. Jiranek, Samuel S. Wellman, Michael P. Bolognesi, and Thorsten M. Seyler. “Cost of Aseptic Revision Total Knee Arthroplasty at a Tertiary Medical Center.” J Arthroplasty 36, no. 5 (May 2021): 1729–33. https://doi.org/10.1016/j.arth.2020.11.028.
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    • Goltz, Daniel E., Sean P. Ryan, David E. Attarian, William A. Jiranek, Michael P. Bolognesi, and Thorsten M. Seyler. “A Preoperative Risk Prediction Tool for Discharge to a Skilled Nursing or Rehabilitation Facility After Total Joint Arthroplasty.” J Arthroplasty 36, no. 4 (April 2021): 1212–19. https://doi.org/10.1016/j.arth.2020.10.038.
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    • Hernandez, Nicholas M., Daniel J. Cunningham, Nima Kabirian, Michael A. Mont, William A. Jiranek, Michael P. Bolognesi, and Thorsten M. Seyler. “Angiotensin Receptor Blockers Were Not Associated With Decreased Arthrofibrosis After Total Knee Arthroplasty.” Orthopedics 44, no. 2 (March 2021): e274–80. https://doi.org/10.3928/01477447-20201216-09.
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    • Hernandez, Nicholas M., Michael W. Buchanan, Thorsten M. Seyler, Samuel S. Wellman, Jessica Seidelman, and William A. Jiranek. “1.5-Stage Exchange Arthroplasty for Total Knee Arthroplasty Periprosthetic Joint Infections.” J Arthroplasty 36, no. 3 (March 2021): 1114–19. https://doi.org/10.1016/j.arth.2020.09.048.
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    • Hernandez, Nicholas M., Rushabh M. Vakharia, Michael A. Mont, William A. Jiranek, Michael P. Bolognesi, and Thorsten M. Seyler. “Paget's Disease in Primary Total Hip Arthroplasty Is Associated With Greater In-Hospital Lengths of Stay, Costs, and Complications.” J Arthroplasty 36, no. 2 (February 2021): 623–29. https://doi.org/10.1016/j.arth.2020.08.017.
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    • Kildow, Beau J., Sean P. Ryan, Richard Danilkowicz, Alexander L. Lazarides, Colin Penrose, Michael P. Bolognesi, William Jiranek, and Thorsten M. Seyler. “Next-generation sequencing not superior to culture in periprosthetic joint infection diagnosis.” Bone Joint J 103-B, no. 1 (January 2021): 26–31. https://doi.org/10.1302/0301-620X.103B1.BJJ-2020-0017.R3.
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    • Ryan, Sean P., Christine J. Wu, Johannes F. Plate, Michael P. Bolognesi, William A. Jiranek, and Thorsten M. Seyler. “A Case Complexity Modifier Is Warranted for Primary Total Knee Arthroplasty.” J Arthroplasty 36, no. 1 (January 2021): 37–41. https://doi.org/10.1016/j.arth.2020.07.066.
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    • Lentz, Trevor A., Steven Z. George, Olivia Manickas-Hill, Morven R. Malay, Jonathan O’Donnell, Prakash Jayakumar, William Jiranek, and Richard C. Mather. “What General and Pain-associated Psychological Distress Phenotypes Exist Among Patients with Hip and Knee Osteoarthritis?” Clin Orthop Relat Res 478, no. 12 (December 2020): 2768–83. https://doi.org/10.1097/CORR.0000000000001520.
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    • Kildow, Beau J., Sean P. Ryan, Richard Danilkowicz, Alexander L. Lazarides, Tyler J. Vovos, Michael P. Bolognesi, William A. Jiranek, and Thorsten M. Seyler. “Commercially Available Polymerase Chain Reaction Has Minimal Utility in the Diagnosis of Periprosthetic Joint Infection.” Orthopedics 43, no. 6 (November 1, 2020): 333–38. https://doi.org/10.3928/01477447-20200923-01.
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    • Anastasio, Albert T., Preet S. Patel, John R. Wickman, and William A. Jiranek. “Letter to the Editor on Robot-Assisted Total Knee Arthroplasty Does Not Improve Long-Term Clinical and Radiologic Outcomes.” J Arthroplasty 35, no. 8 (August 2020): 2303–4. https://doi.org/10.1016/j.arth.2020.04.002.
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    • Hernandez, Nicholas M., Daniel J. Cunningham, William A. Jiranek, Michael P. Bolognesi, and Thorsten M. Seyler. “Corrigendum to 'Total Hip Arthroplasty in Patients With Dementia' [The Journal of Arthroplasty 35 (2020) 1667-1670].” J Arthroplasty 35, no. 8 (August 2020): 2306. https://doi.org/10.1016/j.arth.2020.05.014.
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    • Hernandez, Nicholas M., Daniel J. Cunningham, William A. Jiranek, Michael P. Bolognesi, and Thorsten M. Seyler. “Total Hip Arthroplasty in Patients With Dementia.” J Arthroplasty 35, no. 6 (June 2020): 1667-1670.e2. https://doi.org/10.1016/j.arth.2020.01.070.
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    • Hernandez, Nicholas M., Michael W. Buchanan, Mark M. Cullen, Bryan S. Crook, Michael P. Bolognesi, Jessica Seidelman, and William A. Jiranek. “Corynebacterium Total Hip and Knee Arthroplasy Prosthetic Joint Infections.” Arthroplast Today 6, no. 2 (June 2020): 163–68. https://doi.org/10.1016/j.artd.2020.03.008.
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    • Hernandez, Nicholas M., Daniel J. Cunningham, William A. Jiranek, Michael P. Bolognesi, and Thorsten M. Seyler. “Total Knee Arthroplasty in Patients with Dementia.” J Knee Surg, May 27, 2020. https://doi.org/10.1055/s-0040-1712086.
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    • Hong, Cierra S., Cary Politzer, Sean P. Ryan, Samuel S. Wellman, William A. Jiranek, Michael P. Bolognesi, and Thorsten M. Seyler. “Impact of Patent Foramen Ovale on Total Knee Arthroplasty Cerebrovascular Accident Perioperative Management.” Orthopedics 43, no. 3 (May 1, 2020): e151–58. https://doi.org/10.3928/01477447-20200213-06.
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    • Warwick, Hunter, Jonathan O’Donnell, Richard C. Mather, and William Jiranek. “Disparity of health services in patients with knee osteoarthritis before total knee arthroplasty.” Arthroplast Today 6, no. 1 (March 2020): 81–87. https://doi.org/10.1016/j.artd.2019.11.008.
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    • Malay, Morven R., Trevor A. Lentz, Jonathan O’Donnell, Theresa Coles, Richard Chad Mather Iii, and William A. Jiranek. “Development of a Comprehensive, Nonsurgical Joint Health Program for People With Osteoarthritis: A Case Report.” Phys Ther 100, no. 1 (January 23, 2020): 127–35. https://doi.org/10.1093/ptj/pzz150.
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    • Ryan, Sean P., Thomas J. Hopkins, Samuel S. Wellman, William A. Jiranek, Michael P. Bolognesi, and Thorsten M. Seyler. “Undersedation During Total Hip Arthroplasty Reduction Results in Worse Patient Outcomes.” J Arthroplasty 34, no. 12 (December 2019): 3061–64. https://doi.org/10.1016/j.arth.2019.07.020.
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    • Ryan, Sean P., Johannes F. Plate, Collin S. Black, Claire B. Howell, William A. Jiranek, Michael P. Bolognesi, and Thorsten M. Seyler. “Value-Based Care Has Not Resulted in Biased Patient Selection: Analysis of a Single Center's Experience in the Care for Joint Replacement Bundle.” J Arthroplasty 34, no. 9 (September 2019): 1872–75. https://doi.org/10.1016/j.arth.2019.04.052.
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    • Plate, Johannes F., Sean P. Ryan, Collin S. Black, Claire B. Howell, William A. Jiranek, Michael P. Bolognesi, and Thorsten M. Seyler. “No Changes in Patient Selection and Value-Based Metrics for Total Hip Arthroplasty After Comprehensive Care for Joint Replacement Bundle Implementation at a Single Center.” J Arthroplasty 34, no. 8 (August 2019): 1581–84. https://doi.org/10.1016/j.arth.2019.05.016.
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    • Lazarides, Alexander L., Tyler J. Vovos, Gireesh B. Reddy, Beau J. Kildow, Samuel S. Wellman, William A. Jiranek, and Thorsten M. Seyler. “Traditional Laboratory Markers Hold Low Diagnostic Utility for Immunosuppressed Patients With Periprosthetic Joint Infections.” J Arthroplasty 34, no. 7 (July 2019): 1441–45. https://doi.org/10.1016/j.arth.2019.03.013.
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    • Ryan, Sean P., Claire B. Howell, Samuel S. Wellman, David E. Attarian, Michael P. Bolognesi, William A. Jiranek, Solomon Aronson, and Thorsten M. Seyler. “Preoperative Optimization Checklists Within the Comprehensive Care for Joint Replacement Bundle Have Not Decreased Hospital Returns for Total Knee Arthroplasty.” J Arthroplasty 34, no. 7S (July 2019): S108–13. https://doi.org/10.1016/j.arth.2018.12.010.
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    • Ryan, Sean P., Johannes F. Plate, Daniel E. Goltz, David E. Attarian, Samuel S. Wellman, Thorsten M. Seyler, and William A. Jiranek. “Should Medical Severity-Diagnosis Related Group Classification Be Utilized for Reimbursement? An Analysis of Elixhauser Comorbidities and Cost of Care.” J Arthroplasty 34, no. 7 (July 2019): 1312–16. https://doi.org/10.1016/j.arth.2019.02.045.
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    • Hess, S. R., A. C. Waligora, W. A. Jiranek, and G. J. Golladay. “Inflammatory demyelinating polyneuropathy after total hip arthroplasty.” Arthroplasty Today 5, no. 1 (March 1, 2019): 17–20. https://doi.org/10.1016/j.artd.2018.08.003.
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    • Ryan, Sean P., Daniel E. Goltz, Claire B. Howell, William A. Jiranek, David E. Attarian, Michael P. Bolognesi, and Thorsten M. Seyler. “Predicting Costs Exceeding Bundled Payment Targets for Total Joint Arthroplasty.” J Arthroplasty 34, no. 3 (March 2019): 412–17. https://doi.org/10.1016/j.arth.2018.11.012.
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    • Akonjom, Mandus, Andrew Battenberg, David Beverland, Jae-Hyuck Choi, Yale Fillingham, Nicola Gallagher, Seung Beom Han, et al. “General Assembly, Prevention, Blood Conservation: Proceedings of International Consensus on Orthopedic Infections.” J Arthroplasty 34, no. 2S (February 2019): S147–55. https://doi.org/10.1016/j.arth.2018.09.065.
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    • Jiranek, William, James W. M. Kigera, Brian A. Klatt, Fatih Küçükdurmaz, Jay Lieberman, Claus Moser, Kevin Mulhall, et al. “General Assembly, Prevention, Host Risk Mitigation - General Factors: Proceedings of International Consensus on Orthopedic Infections.” J Arthroplasty 34, no. 2S (February 2019): S43–48. https://doi.org/10.1016/j.arth.2018.09.052.
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    • Hess, Shane R., Laura A. Lahaye, Andrew C. Waligora, Adam P. Sima, William A. Jiranek, and Gregory J. Golladay. “Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty.” Eur J Orthop Surg Traumatol 29, no. 1 (January 2019): 125–29. https://doi.org/10.1007/s00590-018-2293-9.
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    • Ryan, Sean P., Benjamin Wooster, William Jiranek, Samuel Wellman, Michael Bolognesi, and Thorsten Seyler. “Outcomes of Conversion Total Hip Arthroplasty From Free Vascularized Fibular Grafting.” J Arthroplasty 34, no. 1 (January 2019): 88–92. https://doi.org/10.1016/j.arth.2018.09.041.
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    • Warwick, Hunter, Andrew George, Claire Howell, Cynthia Green, Thorsten M. Seyler, and William A. Jiranek. “Immediate Physical Therapy following Total Joint Arthroplasty: Barriers and Impact on Short-Term Outcomes.” Adv Orthop 2019 (2019): 6051476. https://doi.org/10.1155/2019/6051476.
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    • Veilleux, Nathan J., Niraj V. Kalore, Jacob A. Wegelin, Josephina A. Vossen, William A. Jiranek, and Jennifer S. Wayne. “Automated femoral version estimation without the distal femur.” J Orthop Res 36, no. 12 (December 2018): 3161–68. https://doi.org/10.1002/jor.24121.
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    • Jiranek, William A. “Introduction: How Should the Joint Surgeon Respond to the Opioid Crisis?” J Arthroplasty 33, no. 11 (November 2018): 3371. https://doi.org/10.1016/j.arth.2018.08.004.
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    • Ryan, Sean P., Marcus DiLallo, David E. Attarian, William A. Jiranek, and Thorsten M. Seyler. “Conversion vs Primary Total Hip Arthroplasty: Increased Cost of Care and Perioperative Complications.” J Arthroplasty 33, no. 8 (August 2018): 2405–11. https://doi.org/10.1016/j.arth.2018.03.006.
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    • Hess, S. R., R. S. O’Connell, C. P. Bednarz, A. C. Waligora, G. J. Golladay, and W. A. Jiranek. “Association of rapidly destructive osteoarthritis of the hip with intra-articular steroid injections.” Arthroplasty Today 4, no. 2 (June 1, 2018): 205–9. https://doi.org/10.1016/j.artd.2017.12.002.
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    • Riddle, Daniel L., Hassan Ghomrawi, William A. Jiranek, Levent Dumenci, Robert A. Perera, and Antonio Escobar. “Appropriateness Criteria for Total Knee Arthroplasty: Additional Comments and Considerations.” J Bone Joint Surg Am 100, no. 4 (February 21, 2018): e22. https://doi.org/10.2106/JBJS.17.00405.
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    • Golladay, Gregory J., Karl R. Balch, David F. Dalury, Jibanananda Satpathy, and William A. Jiranek. “Oral Multimodal Analgesia for Total Joint Arthroplasty.” J Arthroplasty 32, no. 9S (September 2017): S69–73. https://doi.org/10.1016/j.arth.2017.05.002.
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    • Jiranek, William A. “Current Trends in Pain Management in Total Hip and Knee Arthroplasties.” J Arthroplasty 32, no. 9S (September 2017): S68. https://doi.org/10.1016/j.arth.2017.06.035.
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    • Ross, Jeremy A., Anna C. Greenwood, Phillip Sasser, and William A. Jiranek. “Periarticular Injections in Knee and Hip Arthroplasty: Where and What to Inject.” J Arthroplasty 32, no. 9S (September 2017): S77–80. https://doi.org/10.1016/j.arth.2017.05.003.
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    • Tarabichi, Majd, Noam Shohat, Michael M. Kheir, Muyibat Adelani, David Brigati, Sean M. Kearns, Pankajkumar Patel, et al. “Determining the Threshold for HbA1c as a Predictor for Adverse Outcomes After Total Joint Arthroplasty: A Multicenter, Retrospective Study.” J Arthroplasty 32, no. 9S (September 2017): S263-S267.e1. https://doi.org/10.1016/j.arth.2017.04.065.
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    • Crook, Paul D., John R. Owen, Shane R. Hess, Samer M. Al-Humadi, Jennifer S. Wayne, and William A. Jiranek. “Initial Stability of Cemented vs Cementless Tibial Components Under Cyclic Load.” J Arthroplasty 32, no. 8 (August 2017): 2556–62. https://doi.org/10.1016/j.arth.2017.03.039.
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    • Durgin, Chesley F., E Meade Spratley, Jibanananda Satpathy, William A. Jiranek, and Jennifer S. Wayne. “Novel potential marker for native anteversion of the proximal femur.” J Orthop Res 35, no. 8 (August 2017): 1724–31. https://doi.org/10.1002/jor.23455.
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    • Waligora, Andrew C., John R. Owen, Jennifer S. Wayne, Shane R. Hess, Gregory J. Golladay, and William A. Jiranek. “The Effect of Prophylactic Cerclage Wires in Primary Total Hip Arthroplasty: A Biomechanical Study.” J Arthroplasty 32, no. 6 (June 2017): 2023–27. https://doi.org/10.1016/j.arth.2017.01.019.
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    • Riddle, Daniel L., Gregory J. Golladay, William A. Jiranek, and Robert A. Perera. “External Validation of a Prognostic Model for Predicting Nonresponse Following Knee Arthroplasty.” J Arthroplasty 32, no. 4 (April 2017): 1153-1158.e1. https://doi.org/10.1016/j.arth.2016.11.007.
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    • Jiranek, W., and R. Iorio. “Comprehensive Care for Joint Replacement (CJR), a mandatory program with winners and losers.” Seminars in Arthroplasty Jses 27, no. 3 (September 1, 2016): 193–95. https://doi.org/10.1053/j.sart.2016.10.009.
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    • Kalore, Niraj V., Suresh P. R. Cheppalli, William E. Daner, and William A. Jiranek. “Acetabular Dysplasia in Middle-Aged Patients: Periacetabular Osteotomy or Total Hip Arthroplasty?” J Arthroplasty 31, no. 9 (September 2016): 1894–98. https://doi.org/10.1016/j.arth.2016.02.032.
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    • Jiranek, William. “Modifiable Risk Factors in Total Joint Arthroplasty.” J Arthroplasty 31, no. 8 (August 2016): 1619. https://doi.org/10.1016/j.arth.2016.06.017.
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    • Golladay, Gregory J., Jibanananda Satpathy, and William A. Jiranek. “Patient Optimization-Strategies That Work: Malnutrition.” The Journal of Arthroplasty 31, no. 8 (August 2016): 1631–34. https://doi.org/10.1016/j.arth.2016.03.027.
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    • Curtin, Brian M., Lucas C. Armstrong, Brandon T. Bucker, Susan M. Odum, and William A. Jiranek. “Patient Radiation Exposure During Fluoro-Assisted Direct Anterior Approach Total Hip Arthroplasty.” J Arthroplasty 31, no. 6 (June 2016): 1218–21. https://doi.org/10.1016/j.arth.2015.12.012.
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    • Maradit Kremers, Hilal, Dirk R. Larson, Mohamed Noureldin, Cathy D. Schleck, William A. Jiranek, and Daniel J. Berry. “Long-Term Mortality Trends After Total Hip and Knee Arthroplasties: A Population-Based Study.” J Arthroplasty 31, no. 6 (June 2016): 1163–69. https://doi.org/10.1016/j.arth.2015.12.010.
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    • Goldman, Ashton H., Lucas C. Armstrong, John R. Owen, Jennifer S. Wayne, and William A. Jiranek. “Does Increased Coefficient of Friction of Highly Porous Metal Increase Initial Stability at the Acetabular Interface?” J Arthroplasty 31, no. 3 (March 2016): 721–26. https://doi.org/10.1016/j.arth.2015.10.012.
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    • Meneghini, R Michael, Jason R. Hull, Glenn S. Russo, Jay R. Lieberman, and William A. Jiranek. “Porous Tantalum Buttress Augments for Severe Acetabular Posterior Column Deficiency.” Surg Technol Int 27 (November 2015): 240–44.
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    • Maradit Kremers, Hilal, Dirk R. Larson, Cynthia S. Crowson, Walter K. Kremers, Raynard E. Washington, Claudia A. Steiner, William A. Jiranek, and Daniel J. Berry. “Prevalence of Total Hip and Knee Replacement in the United States.” J Bone Joint Surg Am 97, no. 17 (September 2, 2015): 1386–97. https://doi.org/10.2106/JBJS.N.01141.
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    • Jiranek, William A., Andrew C. Waligora, Shane R. Hess, and Gregory L. Golladay. “Surgical Treatment of Prosthetic Joint Infections of the Hip and Knee: Changing Paradigms?” J Arthroplasty 30, no. 6 (June 2015): 912–18. https://doi.org/10.1016/j.arth.2015.03.014.
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    • Kannan, Arun, Robert S. O’Connell, Niraj Kalore, Brian M. Curtin, Jason R. Hull, and William A. Jiranek. “Revision TKA for Flexion Instability Improves Patient Reported Outcomes.” J Arthroplasty 30, no. 5 (May 2015): 818–21. https://doi.org/10.1016/j.arth.2014.12.010.
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    • Riddle, D. L., and W. A. Jiranek. “Knee osteoarthritis radiographic progression and associations with pain and function prior to knee arthroplasty: a multicenter comparative cohort study.” Osteoarthritis Cartilage 23, no. 3 (March 2015): 391–96. https://doi.org/10.1016/j.joca.2014.12.013.
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    • Riddle, Daniel L., Robert A. Perera, William A. Jiranek, and Levent Dumenci. “Using surgical appropriateness criteria to examine outcomes of total knee arthroplasty in a United States sample.” Arthritis Care Res (Hoboken) 67, no. 3 (March 2015): 349–57. https://doi.org/10.1002/acr.22428.
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    • Riddle, Daniel L., Curtis W. Hayes, and William A. Jiranek. “Reply: To PMID 24974958.” Arthritis Rheumatol 67, no. 2 (February 2015): 585–86. https://doi.org/10.1002/art.38929.
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    • Riddle, Daniel L., Robert Perera, William A. Jiranek, and Levent Dumenci. “Letter to the editor: preoperative pain and function profiles reflect consistent TKA patient selection among US surgeons.” Clin Orthop Relat Res 473, no. 1 (January 2015): 393–94. https://doi.org/10.1007/s11999-014-4035-6.
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    • Franklin, Patricia D., David Lewallen, Kevin Bozic, Brian Hallstrom, William Jiranek, and David C. Ayers. “Implementation of patient-reported outcome measures in U.S. Total joint replacement registries: rationale, status, and plans.” J Bone Joint Surg Am 96 Suppl 1 (December 17, 2014): 104–9. https://doi.org/10.2106/JBJS.N.00328.
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    • Novak, Clifford C., Andrew R. Hsu, Craig J. Della Valle, Anastasia K. Skipor, Patricia Campbell, Harlan C. Amstutz, William A. Jiranek, Aham Onyike, Xavier F. Pombar, and Joshua J. Jacobs. “Metal ion levels in maternal and placental blood after metal-on-metal total hip arthroplasty.” American Journal of Orthopedics (Belle Mead, N.J.) 43, no. 12 (December 2014): E304–8.
    • Higgins, Sean W., E Meade Spratley, Richard A. Boe, Curtis W. Hayes, William A. Jiranek, and Jennifer S. Wayne. “A novel approach for determining three-dimensional acetabular orientation: results from two hundred subjects.” J Bone Joint Surg Am 96, no. 21 (November 5, 2014): 1776–84. https://doi.org/10.2106/JBJS.L.01141.
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    • Cipriano, Cara, Aparna Maiti, Gregory Hale, and William Jiranek. “The host response: Toll-like receptor expression in periprosthetic tissues as a biomarker for deep joint infection.” J Bone Joint Surg Am 96, no. 20 (October 15, 2014): 1692–98. https://doi.org/10.2106/JBJS.M.01295.
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    • Riddle, Daniel L., William A. Jiranek, and Curtis W. Hayes. “Use of a validated algorithm to judge the appropriateness of total knee arthroplasty in the United States: a multicenter longitudinal cohort study.” Arthritis Rheumatol 66, no. 8 (August 2014): 2134–43. https://doi.org/10.1002/art.38685.
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    • Kannan, Arun, John R. Owen, Jennifer S. Wayne, and William A. Jiranek. “Loosely implanted cementless stems may become rotationally stable after loading.” Clin Orthop Relat Res 472, no. 7 (July 2014): 2231–36. https://doi.org/10.1007/s11999-014-3577-y.
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    • Fehring, Keith A., John R. Owen, Anton A. Kurdin, Jennifer S. Wayne, and William A. Jiranek. “Initial stability of press-fit acetabular components under rotational forces.” The Journal of Arthroplasty 29, no. 5 (May 2014): 1038–42. https://doi.org/10.1016/j.arth.2013.10.009.
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    • Lichstein, Paul, Thorsten Gehrke, Adolph Lombardi, Carlo Romano, Ian Stockley, George Babis, Jerzy Bialecki, et al. “One-stage vs two-stage exchange.” J Arthroplasty 29, no. 2 Suppl (February 2014): 108–11. https://doi.org/10.1016/j.arth.2013.09.048.
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    • Lichstein, Paul, Thorsten Gehrke, Adolph Lombardi, Carlo Romano, Ian Stockley, George Babis, Jerzy Bialecki, et al. “One-stage versus two-stage exchange.” J Orthop Res 32 Suppl 1 (January 2014): S141–46. https://doi.org/10.1002/jor.22558.
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    • Riddle, Daniel L., Robert A. Perera, Paul W. Stratford, William A. Jiranek, and Levent Dumenci. “Progressing toward, and recovering from, knee replacement surgery: a five-year cohort study.” Arthritis and Rheumatism 65, no. 12 (December 2013): 3304–13. https://doi.org/10.1002/art.38139.
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    • Riddle, Daniel L., William A. Jiranek, and Jason R. Hull. “Validity and reliability of radiographic knee osteoarthritis measures by arthroplasty surgeons.” Orthopedics 36, no. 1 (January 2013): e25–32. https://doi.org/10.3928/01477447-20121217-14.
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    • Peters, Christopher L., Paul E. Beaulé, Martin Beck, Moritz Tannast, William Jiranek, and Rafael J. Sierra. “Report of breakout session: Strategies to improve hip preservation training.” Clin Orthop Relat Res 470, no. 12 (December 2012): 3467–69. https://doi.org/10.1007/s11999-012-2449-6.
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    • Xing, Zhiqing, Jonathan Katz, and William Jiranek. “Unicompartmental knee arthroplasty: factors influencing the outcome.” J Knee Surg 25, no. 5 (November 2012): 369–73. https://doi.org/10.1055/s-0031-1299666.
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    • Riddle, Daniel L., William A. Jiranek, Robert S. Neff, Derek Whitaker, and Jason R. Hull. “Extent of tibiofemoral osteoarthritis before knee arthroplasty: multicenter data from the osteoarthritis initiative.” Clin Orthop Relat Res 470, no. 10 (October 2012): 2836–42. https://doi.org/10.1007/s11999-012-2328-1.
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    • Riddle, Daniel L., Xiangrong Kong, and William A. Jiranek. “Factors associated with rapid progression to knee arthroplasty: complete analysis of three-year data from the osteoarthritis initiative.” Joint Bone Spine 79, no. 3 (May 2012): 298–303. https://doi.org/10.1016/j.jbspin.2011.05.005.
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    • Jiranek, William. “Approaches for revision total hip replacement.” Instr Course Lect 61 (2012): 295–302.
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    • Riddle, D. L., X. Kong, and W. A. Jiranek. “Factors associated with a rapid progression to knee arthroplasty: Comprehensive data analysis of the three years of the "Osteoarthritis Initiative".” Revue Du Rhumatisme (Edition Francaise) 79, no. 3 (January 1, 2012): 251–57. https://doi.org/10.1016/j.rhum.2011.05.024.
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    • Goldberg, V. M., J. Buckwalter, M. Halpin, W. Jiranek, W. Mihalko, M. Pinzur, B. Rohan, et al. “Recommendations of the OARSI FDA Osteoarthritis Devices Working Group.” Osteoarthritis Cartilage 19, no. 5 (May 2011): 509–14. https://doi.org/10.1016/j.joca.2011.02.017.
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    • Odum, S. M., T. K. Fehring, A. V. Lombardi, B. M. Zmistowski, N. M. Brown, J. T. Luna, K. A. Fehring, et al. “Irrigation and debridement for periprosthetic infections: Does the organism matter?” Journal of Arthroplasty 26, no. SUPPL. 6 (January 1, 2011): 114–18. https://doi.org/10.1016/j.arth.2011.03.031.
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    • Riddle, Daniel L., James B. Wade, and William A. Jiranek. “Major depression, generalized anxiety disorder, and panic disorder in patients scheduled for knee arthroplasty.” J Arthroplasty 25, no. 4 (June 2010): 581–88. https://doi.org/10.1016/j.arth.2009.04.002.
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    • Riddle, Daniel L., James B. Wade, William A. Jiranek, and Xiangrong Kong. “Preoperative pain catastrophizing predicts pain outcome after knee arthroplasty.” Clin Orthop Relat Res 468, no. 3 (March 2010): 798–806. https://doi.org/10.1007/s11999-009-0963-y.
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    • Farr, Jack, and William A. Jiranek. “Sports after knee arthroplasty: partial versus total knee arthroplasty.” Phys Sportsmed 37, no. 4 (December 2009): 53–61. https://doi.org/10.3810/psm.2009.12.1742.
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    • Riddle, Daniel L., Xiangrong Kong, and William A. Jiranek. “Two-year incidence and predictors of future knee arthroplasty in persons with symptomatic knee osteoarthritis: preliminary analysis of longitudinal data from the osteoarthritis initiative.” Knee 16, no. 6 (December 2009): 494–500. https://doi.org/10.1016/j.knee.2009.04.002.
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    • Sambandam, Senthil Nathan, Jason Hull, and William A. Jiranek. “Factors predicting the failure of Bernese periacetabular osteotomy: a meta-regression analysis.” Int Orthop 33, no. 6 (December 2009): 1483–88. https://doi.org/10.1007/s00264-008-0643-7.
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    • Anand, Ashish, Fred McGlynn, and William Jiranek. “Metal hypersensitivity: can it mimic infection?” J Arthroplasty 24, no. 5 (August 2009): 826.e25-826.e28. https://doi.org/10.1016/j.arth.2008.05.002.
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    • Iorio, Richard, William J. Robb, William L. Healy, Daniel J. Berry, William J. Hozack, Richard F. Kyle, David G. Lewallen, et al. “Orthopaedic surgeon workforce and volume assessment for total hip and knee replacement in the United States: preparing for an epidemic.” J Bone Joint Surg Am 90, no. 7 (July 2008): 1598–1605. https://doi.org/10.2106/JBJS.H.00067.
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    • Riddle, Daniel L., William A. Jiranek, and Fred J. McGlynn. “Yearly incidence of unicompartmental knee arthroplasty in the United States.” J Arthroplasty 23, no. 3 (April 2008): 408–12. https://doi.org/10.1016/j.arth.2007.04.012.
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    • Goodman, Stuart B., William Jiranek, Edward Petrow, and Alan W. Yasko. “The effects of medications on bone.” J Am Acad Orthop Surg 15, no. 8 (August 2007): 450–60. https://doi.org/10.5435/00124635-200708000-00002.
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    • Ramage, Samuel C., Nicole H. Urban, William A. Jiranek, Aparna Maiti, and Matthew J. Beckman. “Expression of RANKL in osteolytic membranes: association with fibroblastic cell markers.” J Bone Joint Surg Am 89, no. 4 (April 2007): 841–48. https://doi.org/10.2106/JBJS.F.00655.
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    • Jiranek, William A., Arlen D. Hanssen, and A Seth Greenwald. “Antibiotic-loaded bone cement for infection prophylaxis in total joint replacement.” J Bone Joint Surg Am 88, no. 11 (November 2006): 2487–2500. https://doi.org/10.2106/JBJS.E.01126.
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    • Liacouras, Peter C., John R. Owen, William A. Jiranek, and Jennifer S. Wayne. “Effect of pigmentation on the mechanical and polymerization characteristics of bone cement.” J Arthroplasty 21, no. 4 (June 2006): 606–11. https://doi.org/10.1016/j.arth.2005.07.006.
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    • Jiranek, William. “Thermal manipulation of bone cement.” Orthopedics 28, no. 8 Suppl (August 2005): s863–66. https://doi.org/10.3928/0147-7447-20050802-12.
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    • Jiranek, William. “Antibiotic-loaded cement in total hip replacement: current indications, efficacy, and complications.” Orthopedics 28, no. 8 Suppl (August 2005): s873–77. https://doi.org/10.3928/0147-7447-20050802-14.
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    • Qiu, J., M. J. Beckman, J. Qian, and W. Jiranek. “Simultaneous labeling of mast cell proteases and protease mRNAs at the bone-implant interface of aseptically loosened hip implants.” J Orthop Res 23, no. 4 (July 2005): 942–48. https://doi.org/10.1016/j.orthres.2005.04.008.
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    • Noble, Andrew R., Daniel B. Branham, Mark C. Willis, John R. Owen, Benjamin W. Cramer, Jennifer S. Wayne, and William A. Jiranek. “Mechanical effects of the extended trochanteric osteotomy.” J Bone Joint Surg Am 87, no. 3 (March 2005): 521–29. https://doi.org/10.2106/JBJS.C.00759.
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    • Hamlin, B., M. Barrett, and W. Jiranek. “The role of computer assisted surgery in minimally invasive joint replacement surgery.” Seminars in Arthroplasty Jses 16, no. 3 (January 1, 2005): 239–47. https://doi.org/10.1053/j.sart.2005.10.017.
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    • Caldwell, Paul E., Barry A. Bohlen, John R. Owen, Michael H. Brown, Barton Harris, Jennifer S. Wayne, and William A. Jiranek. “Dynamic confirmation of fixation techniques of the tibial tubercle osteotomy.” Clin Orthop Relat Res, no. 424 (July 2004): 173–79. https://doi.org/10.1097/01.blo.0000130205.57095.a2.
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    • Dalury, David F., and William A. Jiranek. “The incidence of heterotopic ossification after total knee arthroplasty.” The Journal of Arthroplasty 19, no. 4 (June 2004): 447–52. https://doi.org/10.1016/j.arth.2003.12.064.
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    • Mendes, Michael W., Paul Caldwell, and William A. Jiranek. “The results of tibial tubercle osteotomy for revision total knee arthroplasty.” J Arthroplasty 19, no. 2 (February 2004): 167–74. https://doi.org/10.1016/j.arth.2003.08.013.
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    • Jiranek, W. A., D. R. Whiddon, and W. T. Johnstone. “Late loosening of press-fit cementless acetabular components.” Clin Orthop Relat Res, no. 418 (January 2004): 172–78. https://doi.org/10.1097/00003086-200401000-00028.
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    • Dalury, David F., William Jiranek, Jeffrey Pierson, and Sara E. Pearson. “The long-term outcome of total knee patients with moderate loss of motion.” J Knee Surg 16, no. 4 (October 2003): 215–20.
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    • Sluss, J. R., J. P. Liberti, W. A. Jiranek, J. S. Wayne, and W. A. Zuelzer. “pN collagen type III within tendon grafts used for anterior cruciate ligament reconstruction.” J Orthop Res 19, no. 5 (September 2001): 852–57. https://doi.org/10.1016/S0736-0266(01)00014-6.
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    • Davis, K., P. Caldwell, J. Wayne, and W. A. Jiranek. “Mechanical comparison of fixation techniques for the tibial tubercle osteotomy.” Clin Orthop Relat Res, no. 380 (November 2000): 241–49. https://doi.org/10.1097/00003086-200011000-00033.
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    • Yin, C., J. S. Wayne, W. A. Jiranek, and W. A. Zuelzer. “Differences in mRNA expression patterns between patellar tendons and anterior cruciate ligaments of immature pigs.” J Orthop Res 17, no. 6 (November 1999): 823–28. https://doi.org/10.1002/jor.1100170606.
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    • Dalury, D. F., and W. A. Jiranek. “A comparison of the midvastus and paramedian approaches for total knee arthroplasty.” J Arthroplasty 14, no. 1 (January 1999): 33–37. https://doi.org/10.1016/s0883-5403(99)90199-7.
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    • Lassus, J., J. Salo, W. A. Jiranek, S. Santavirta, J. Nevalainen, M. Matucci-Cerinic, P. Horák, and Y. Konttinen. “Macrophage activation results in bone resorption.” Clin Orthop Relat Res, no. 352 (July 1998): 7–15.
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    • Yin, C., J. S. Wayne, W. A. Jiranek, and W. A. Zuelzer. “Biochemical and molecular homogeneity in the patellar tendon of the immature pig.” J Orthop Res 15, no. 5 (September 1997): 712–18. https://doi.org/10.1002/jor.1100150513.
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    • Bal, B. S., W. A. Jiranek, M. Jasty, and W. H. Harris. “Periprosthetic femoral osteolysis around an uncemented nonmodular Moore prosthesis.” J Arthroplasty 12, no. 3 (April 1997): 346–49. https://doi.org/10.1016/s0883-5403(97)90035-8.
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    • Konttinen, Y. T., V. Waris, J. W. Xu, W. A. Jiranek, T. Sorsa, I. Virtanen, and S. Santavirta. “Transforming growth factor-beta 1 and 2 in the synovial-like interface membrane between implant and bone in loosening of total hip arthroplasty.” J Rheumatol 24, no. 4 (April 1997): 694–701.
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    • Jiranek, W., M. Jasty, J. T. Wang, C. Bragdon, H. Wolfe, M. Goldberg, and W. Harris. “Tissue response to particulate polymethylmethacrylate in mice with various immune deficiencies.” J Bone Joint Surg Am 77, no. 11 (November 1995): 1650–61. https://doi.org/10.2106/00004623-199511000-00003.
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    • Alman, B. A., S. P. Naber, R. M. Terek, W. A. Jiranek, M. J. Goldberg, and H. J. Wolfe. “Platelet-derived growth factor in fibrous musculoskeletal disorders: a study of pathologic tissue sections and in vitro primary cell cultures.” J Orthop Res 13, no. 1 (January 1995): 67–77. https://doi.org/10.1002/jor.1100130111.
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    • Terek, R. M., W. A. Jiranek, M. J. Goldberg, H. J. Wolfe, and B. A. Alman. “The expression of platelet-derived growth-factor gene in Dupuytren contracture.” J Bone Joint Surg Am 77, no. 1 (January 1995): 1–9. https://doi.org/10.2106/00004623-199501000-00001.
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    • Jasty, M., C. Bragdon, W. Jiranek, H. Chandler, W. Maloney, and W. H. Harris. “Etiology of osteolysis around porous-coated cementless total hip arthroplasties.” Clin Orthop Relat Res, no. 308 (November 1994): 111–26.
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    • Buechel, F. F., D. Drucker, M. Jasty, W. Jiranek, and W. H. Harris. “Osteolysis around uncemented acetabular components of cobalt-chrome surface replacement hip arthroplasty.” Clin Orthop Relat Res, no. 298 (January 1994): 202–11.
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    • Jiranek, W. A., M. Machado, M. Jasty, D. Jevsevar, H. J. Wolfe, S. R. Goldring, M. J. Goldberg, and W. H. Harris. “Production of cytokines around loosened cemented acetabular components. Analysis with immunohistochemical techniques and in situ hybridization.” J Bone Joint Surg Am 75, no. 6 (June 1993): 863–79. https://doi.org/10.2106/00004623-199306000-00007.
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    • Jasty, M., W. Jiranek, and W. H. Harris. “Acrylic fragmentation in total hip replacements and its biological consequences.” Clin Orthop Relat Res, no. 285 (December 1992): 116–28.
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    • Jiranek, W. A., L. K. Ruby, L. B. Millender, M. S. Bankoff, and A. H. Newberg. “Long-term results after Russe bone-grafting: the effect of malunion of the scaphoid.” J Bone Joint Surg Am 74, no. 8 (September 1992): 1217–28.
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    • ALMAN, B. A., W. A. JIRANEK, S. P. NABER, R. M. TEREK, M. J. GOLDBERG, and H. J. WOLFE. “INAPPROPRIATE C-SIS PROTOONCOGENE EXPRESSION IN FIBROUS DYSPLASIA - AN INSITU HYBRIDIZATION AND PCR STUDY.” Laboratory Investigation 66, no. 1 (January 1992): A2–A2.
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    • JIRANEK, W. A., B. A. ALMAN, R. M. TEREK, S. P. NABER, L. K. RUBY, M. J. GOLDBERG, and H. J. WOLFE. “INSITU HYBRIDIZATION TO LOCALIZE C-SIS PROTOONCOGENE EXPRESSION IN DUPUYTRENS FIBROMATOSIS.” Laboratory Investigation 66, no. 1 (January 1992): A7–A7.
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    • Dellon, A. L., W. A. Seiler, and W. A. Jiranek. “Teaching the technique of microsurgical intraneural neurolysis.” J Reconstr Microsurg 3, no. 2 (January 1987): 137–41. https://doi.org/10.1055/s-2007-1006976.
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    • Mason, Michael J., Gregory Golladay, William Jiranek, Brian Cameron, Joel J. Silverman, Nikola M. Zaharakis, and Paul Plonski. “Depression Moderates the Relationship Between Pain and the Nonmedical Use of Opioid Medication Among Adult Outpatients.” J Addict Med 10, no. 6 (n.d.): 408–13. https://doi.org/10.1097/ADM.0000000000000253.
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  • Book Sections

    • Hozack, W., C. Duncan, A. Herman, E. Hansen, M. W. Pagnano, J. L. Howard, J. P. McAuley, et al. “Surgical approaches and bearing surfaces.” In Orthopaedic Knowledge Update: Hip and Knee Reconstruction 5, 345–66, 2018.
    • Tocks, G. A., W. A. Jiranek, J. Satpathy, and J. S. Wayne. “Biomechanics of the knee.” In Orthopaedic Knowledge Update: Hip and Knee Reconstruction 5, 85–93, 2018.
    • Kannan, A., and W. A. Jiranek. “Metal on polyethylene.” In The Adult Hip: Hip Arthroplasty Surgery: Third Edition, Vol. 2, 2015.
    • Armstrong, L., and W. A. Jiranek. “Complex primary total knee arthroplasty: Management of extra-articular deformity.” In Complex Primary and Revision Total Knee Arthroplasty: A Clinical Casebook, 55–68, 2015. https://doi.org/10.1007/978-3-319-18350-3_5.
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    • Jiranek, W. A. “Acetabular revision with metal shell retention.” In Revision Total Hip and Knee Arthroplasty, 125–31, 2012.

  • Conference Papers

    • Malay, M. R., T. A. Lentz, J. O’Donnell, Mather R. C. III, and W. A. Jiranek. “EARLY OUTCOMES OF A LONGITUDINAL, COMPREHENSIVE LIFESTYLE AND BEHAVIORAL HEALTH MANAGEMENT PROGRAM FOR OSTEOARTHRITIS IN THE UNITED STATES.” In Osteoarthritis and Cartilage, 28:S158–59, 2020.
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    • Li, N., A. Swiecicki, N. Said, J. O’Donnell, W. A. Jiranek, and M. A. Mazurowski. “Automatic Kellgren-Lawrence grade estimation driven deep learning algorithms.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 11314, 2020. https://doi.org/10.1117/12.2551392.
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    • Swiecicki, A., N. Said, J. O’Donnell, M. Buda, N. Li, W. A. Jiranek, and M. A. Mazurowski. “Automatic estimation of knee joint space narrowing by deep learning segmentation algorithms.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 11314, 2020. https://doi.org/10.1117/12.2551377.
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    • Maiti, Aparna, and William A. Jiranek. “Inhibition of Methicillin-resistant Staphylococcus aureus-induced cytokines mRNA production in human bone marrow derived mesenchymal stem cells by 1,25-dihydroxyvitamin D3.” In Bmc Cell Biol, 15:11, 2014. https://doi.org/10.1186/1471-2121-15-11.
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    • Fehring, Thomas K., Susan M. Odum, Keith R. Berend, William A. Jiranek, Javad Parvizi, Kevin J. Bozic, Craig J. Della Valle, and Terence J. Gioe. “Failure of irrigation and débridement for early postoperative periprosthetic infection.” In Clin Orthop Relat Res, 471:250–57, 2013. https://doi.org/10.1007/s11999-012-2373-9.
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    • Kalore, Niraj V., and William A. Jiranek. “Save the torn labrum in hips with borderline acetabular coverage.” In Clin Orthop Relat Res, 470:3406–13, 2012. https://doi.org/10.1007/s11999-012-2499-9.
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    • Riddle, D. L., W. Jiranek, and J. Hull. “Extent of tibiofemoral osteoarthritis prior to knee arthroplasty: multicenter data from the osteoarthritis initiative.” In Osteoarthritis and Cartilage, 20:S227–S227. Elsevier BV, 2012. https://doi.org/10.1016/j.joca.2012.02.369.
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    • Maiti, Aparna, and William Jiranek. “Vitamin D suppresses staphylococcus mediated inflammation by inhibiting NR4A2 activity in human mesenchymal stem cells.” In Faseb Journal, Vol. 25. FEDERATION AMER SOC EXP BIOL, 2011.
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    • Harris, Barton, John R. Owen, Jennifer S. Wayne, and William A. Jiranek. “Does femoral component loosening predispose to femoral fracture?: an in vitro comparison of cemented hips.” In Clin Orthop Relat Res, 468:497–503, 2010. https://doi.org/10.1007/s11999-009-1034-0.
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    • Jiranek, William A. “Acetabular liner fixation by cement.” In Clin Orthop Relat Res, 217–23, 2003. https://doi.org/10.1097/01.blo.0000096805.78689.8b.
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    • Yin, C., W. A. Jiranek, P. Vaughan, and J. A. Cardea. “Differential messenger ribonucleic acid expression in aggressive versus linear periprosthetic osteolysis.” In Clin Orthop Relat Res, 95–104, 1998.
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    • Yin, C., K. E. Loesser, W. A. Jiranek, J. Y. Qiu, and F. N. Briggs. “Mechanical, histological and molecular biological studies on latissimus dorsi muscles conditioned for myocardioplasty.” In Southern Biomedical Engineering Conference  Proceedings, 213–15, 1995.

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