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William Ferris Malcolm

Professor of Pediatrics
Pediatrics, Neonatology
Box 102509 DUMC, Durham, NC 27710
2400 Pratt St, Durham, NC 27705

Overview


Gastro-esophageal reflux in premature infants
Feeding problems in preterm and high risk infants
Feeding and respiratory problems in infants with vocal cord dysfunction
Neonatal morbidities affecting neuro-developmental outcome in preterm infants
Interventions improving neuro-developmental outcome in high risk infants
Neonatal abstinence syndrome
Convalescent and follow-up care of high risk infants

Current Appointments & Affiliations


Professor of Pediatrics · 2021 - Present Pediatrics, Neonatology, Pediatrics
Clinical Professor in the School of Nursing · 2017 - Present School of Nursing

In the News


Published July 5, 2017
Clinical Trial Saves Babys Lungs

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Recent Publications


Hydrocortisone in Preterm Infants and School-Age Functional Outcomes: Follow-Up of a Randomized Clinical Trial.

Journal Article JAMA Pediatr · December 8, 2025 IMPORTANCE: Bronchopulmonary dysplasia (BPD) is the most common in-hospital morbidity of prematurity, associated with significant long-term medical and neurodevelopmental sequelae and health resource utilization. The Neonatal Research Network (NRN) Hydroco ... Full text Link to item Cite

Outcomes of extremely preterm infants exposed to prolonged prelabor rupture of membranes before 24 weeks of gestation.

Journal Article Am J Obstet Gynecol · August 2025 BACKGROUND: Preterm prelabor rupture of membranes before or around the limit of fetal viability is associated with serious maternal and neonatal complications, including chorioamnionitis, extremely preterm birth, and pulmonary hypoplasia. OBJECTIVE: This s ... Full text Link to item Cite

Darbepoetin, Red Cell Mass, and Neuroprotection in Preterm Infants: A Randomized Clinical Trial.

Journal Article JAMA Pediatr · August 1, 2025 IMPORTANCE: Previous studies suggest that administration of erythropoiesis-stimulating agents darbepoetin or erythropoietin to preterm infants results in fewer transfusions, fewer donor exposures, and improved neurodevelopmental outcome. OBJECTIVE: To dete ... Full text Link to item Cite
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Recent Grants


North Carolina Clinical Center for the Eunice Kennedy Shiver NICHD Cooperative Multicenter Neonatal Research Network

ResearchCo Investigator · Awarded by National Institutes of Health · 2001 - 2030

The Darbepoetin Kindergarten Development Study (Darbe-KIDS)

ResearchPrincipal Investigator · Awarded by Research Triangle Institute International · 2023 - 2028

The Darbepoetin Kindergarten Development Study (Darbe-KIDS)- Capitation Funding

ResearchPrincipal Investigator · Awarded by Research Triangle Institute International · 2023 - 2026

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Education, Training & Certifications


University of Minnesota, Twin Cities · 1998 M.D.