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Wilton Bryan Williams

Associate Professor in Surgery
Surgery, Surgical Sciences
Box 103010, Durham, NC 27710
2 Genome Ct, Durham, NC 27710

Research Interests


HIV-1 immunobiology
HIV-1 vaccination
B cell responses to HIV-1
Non-human primate models for HIV
Microbiome
Modulation of vaccine-induced responses by gut microbiome

Selected Grants


Interdisciplinary Research Training Program in AIDS

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2010 - 2030

Persistent Immunogenicity of IDLV delivering membrane tethered Native-Like HIV-1 Envelope Trimers

ResearchCo-Principal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2025 - 2030

Mechanisms of Early-life Immunity Associated with HIV-1 Vaccine-induced Neutralizing Antibody Responses

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2030

Advanced Immunobiology Traning Program for Surgeons

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029

Neonatal Immunity to novel TF SHIVs

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2029

Multivalent mRNA HIV vaccine using Envelopes from recently circulating viruses.

ResearchMentor · Awarded by National Institutes of Health · 2025 - 2028

Advancing communication strategies to support future HIV vaccine use among African Americans in the South

ResearchCo-Principal Investigator · Awarded by Wake Forest University School Of Medicine · 2025 - 2028

Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 2022 - 2027

SOSIP-NP/mRNA combination for novel preventive and therapeutic HIV-1 vaccine regimens

ResearchPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

SHIV/HIV Env-Antibody Coevolution as a Guide to Iterative Vaccine Design

ResearchCo Investigator · Awarded by University of Pennsylvania · 2017 - 2027

Structural characterization of Fab-dimerized glycan-reactive antibodies that neutralize HIV-1

ResearchCo-Principal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2021 - 2026

Research Training in Allergy and Clinical Immunology

Inst. Training Prgm or CMEMentor · Awarded by University of North Carolina - Chapel Hill · 2000 - 2026

Advancing communication strategies to support future HIV vaccine use among African Americans in the South.

ResearchCo Investigator · Awarded by National Institutes of Health · 2023 - 2023

Immunogen Design of HIV Sequential Envelopes Derived from SHIV-infected Macaques

ResearchPrincipal Investigator · Awarded by University of Pennsylvania · 2017 - 2023

Immunity to novel T/F SHIVs: variability in the co-evolution of virus and host immunity

ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2022