Wissam Mohammad Aly Kourany

Journal Article Clin Kidney J · December 2021 BACKGROUND: Transitioning to maintenance hemodialysis (HD) is a vulnerable period for persons with end-stage renal disease (ESRD), punctuated by high rates of depression, hospitalizations and death. Screening for depression during this time may help to imp ... Full text Link to item Cite

Infective Endocarditis in Patients on Chronic Hemodialysis.

Journal Article J Am Coll Cardiol · April 6, 2021 BACKGROUND: Infective endocarditis (IE) is a common and serious complication in patients receiving chronic hemodialysis (HD). OBJECTIVES: This study sought to investigate whether there are significant differences in complications, cardiac surgery, relapses ... Full text Link to item Cite

Development, implementation and user experience of the Veterans Health Administration (VHA) dialysis dashboard.

Journal Article BMC Nephrol · April 16, 2020 BACKGROUND: Adults with end-stage renal disease (ESRD) requiring chronic dialysis continue to suffer from poor health outcomes and represent a population rightfully targeted for quality improvement. Electronic dashboards are increasingly used in healthcare ... Full text Link to item Cite

Site of Care and Health Outcomes of Veterans Undergoing Maintenance Dialysis.

Journal Article Clin J Am Soc Nephrol · July 6, 2018 Full text Link to item Cite

Endothelial cell autoantibodies in predicting declining renal function, end-stage renal disease, or death in adult type 2 diabetic nephropathy

Journal Article Frontiers in Endocrinology · January 1, 2014 Albuminuria is a strong predictor of diabetic nephropathy chronic kidney disease outcomes. Yet, therapeutic albuminuria-lowering has not consistently translated into a reduction in clinical events suggesting the involvement of additional pathogenic factors ... Full text Cite

Clinical characteristics and outcomes of diabetic patients with Staphylococcus aureus bacteremia and endocarditis.

Journal Article Eur J Clin Microbiol Infect Dis · December 2009 The complications from S. aureus bacteremia (SAB) and infective endocarditis (SAIE) are higher in patients with diabetes. We summarize the characteristics and outcome of diabetic patients enrolled in a multicenter trial of daptomycin vs. standard therapy f ... Full text Link to item Cite

Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha.

Journal Article Mol Endocrinol · June 2009 Collectrin is a downstream target of the transcription factor hepatocyte nuclear factor-1alpha (HNF-1alpha), which is mutated in maturity-onset diabetes of the young subtype 3 (MODY3). Evidence from transgenic mouse models with collectrin overexpression in ... Full text Link to item Cite

Aminoaciduria and altered renal expression of luminal amino acid transporters in mice lacking novel gene collectrin.

Journal Article Am J Physiol Renal Physiol · February 2007 Defects in renal proximal tubule transport manifest in a number of human diseases. Although variable in clinical presentation, disorders such as Hartnup disease, Dent's disease, and Fanconi syndrome are characterized by wasting of solutes commonly recovere ... Full text Link to item Cite

Early surgery in patients with infective endocarditis: a propensity score analysis.

Journal Article Clin Infect Dis · February 1, 2007 BACKGROUND: An accurate assessment of the predictors of long-term mortality in patients with infective endocarditis is not possible using retrospective data because of inherent treatment biases and predictable imbalances in the distribution of prognostic f ... Full text Link to item Cite

Gender differences in infective endocarditis: pre- and co-morbid conditions lead to different management and outcomes in female patients.

Journal Article Scand J Infect Dis · 2007 The impact of gender on the presenting characteristics, management, and outcomes in infective endocarditis (IE) has not been adequately studied. The goal of our study was to better understand differences in management and outcome of IE between genders. Dat ... Full text Link to item Cite

Galphaq-dependent signaling cascades stimulate water-seeking behavior.

Journal Article Am J Physiol Renal Physiol · October 2006 We used the mouse nephrin promoter to express a constitutively active Galphaq [Galphaq(Q>L)] transgene in mice. As previously reported, the transgene was expressed in kidney, pancreas, and brain, and the kidney phenotype was characterized by albuminuria an ... Full text Link to item Cite

Influence of diabetes mellitus on the clinical manifestations and prognosis of infective endocarditis: a report from the International Collaboration on Endocarditis-Merged Database.

Other Scand J Infect Dis · 2006 The purpose of this investigation was to study the influence of diabetes mellitus (DM) on outcomes of infective endocarditis (IE). Outcomes were compared between 150 diabetic and 905 non-diabetic patients with IE from the International Collaboration on End ... Full text Link to item Cite