Scholars@Duke
Wissam Mansour

Wissam Mansour

Assistant Professor of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
wissam.mansour@duke.edu
Hanes House 330 Trent Drive, Room 117, Durham, NC 27710

Selected Publications

Predictors of respiratory decline in neuromuscular disorders.

Journal Article Respir Med · January 2026 Neuromuscular diseases (NMDs) constitute a heterogeneous group of genetic and acquired disorders that lead to progressive muscle weakness. When the respiratory muscles are involved, impaired ventilation and ineffective airway clearance become a major sourc ... Full text Link to item Cite

Protocol and design of the REPOSE study: a double-blinded, randomised, placebo-controlled trial to evaluate the efficacy of suvorexant to improve postoperative sleep and reduce delirium severity in older patients undergoing non-cardiac surgery.

Journal Article BMJ Open · March 13, 2025 INTRODUCTION: Postoperative delirium occurs in up to 40% of older surgical patients and has been associated with prolonged hospital stays, long-term cognitive impairment and increased 1-year postoperative mortality. Postoperative sleep disturbances may inc ... Full text Link to item Cite

Adding Insult to Injury: Sleep Deficiency in Hospitalized Patients.

Journal Article Sleep Med Clin · December 2024 Sleep deficiency is a common problem in the hospital setting. Contributing factors include preexisting medical conditions, illness severity, the hospital environment, and treatment-related effects. Hospitalized patients are particularly vulnerable to the n ... Full text Link to item Cite

Sleep-related hypoventilation and hypoxemia due to neuromuscular and chest wall disorders

Chapter · January 1, 2023 Sleep-disordered breathing occurs frequently in neuromuscular diseases and chest wall disorders as a result of the effects of normal sleep on ventilation and additional challenges imposed by specific disorders. Patterns of sleep-disordered breathing includ ... Full text Cite

Monitoring and Management of Respiratory Function in Pompe Disease: Current Perspectives.

Journal Article Ther Clin Risk Manag · 2023 Pompe disease (PD) is a neuromuscular disorder caused by a deficiency of acid alpha-glucosidase (GAA) - a lysosomal enzyme responsible for hydrolyzing glycogen. GAA deficiency leads to accumulation of glycogen in lysosomes, causing cellular disruption. The ... Full text Link to item Cite

Submillisievert CT chest for COVID-19 patients in a rural hospital with limited resources

Journal Article Egyptian Journal of Radiology and Nuclear Medicine · December 1, 2022 Background: This is a secondary analysis of prospectively acquired data approved by the hospital institutional board committee. We performed a retrospective chart review of 463 patients who underwent a CT Chest for suspected COVID-19 infection between Apri ... Full text Cite

Adding Insult to Injury: Sleep Deficiency in Hospitalized Patients.

Journal Article Clin Chest Med · June 2022 Sleep deficiency is a common problem in the hospital setting. Contributing factors include preexisting medical conditions, illness severity, the hospital environment, and treatment-related effects. Hospitalized patients are particularly vulnerable to the n ... Full text Link to item Cite

681 Sleep Apnea Severity and COVID-19 Hospitalization Outcomes: Interim Analysis

Journal Article Sleep · May 3, 2021 AbstractIntroductionMillions worldwide have been infected with COVID-19. Risk factors for poor outcomes include older age, obesity, ca ... Full text Cite

A Case of Laryngeal Tuberculosis, Endobronchial Tuberculosis and Pulmonary Tuberculosis Coexistent in an Immunocompetent Host.

Journal Article Cureus · September 29, 2020 Historically associated with poor prognosis seen in advanced disease, laryngeal tuberculosis (LTB) now represents only 1% of all cases of tuberculosis (TB). The incidence of LTB has decreased drastically with the introduction of anti-tubercular drugs. LTB ... Full text Link to item Cite

Pneumopericardium, pneumomediastinum and air travel: A case report in a patient with Gardner syndrome.

Journal Article Respir Med Case Rep · 2020 Featured Publication Onboard aircraft medical emergencies are on the rise as commercial air traffic is increasing. However, thoracic injury secondary to air travel is extremely rare and, most reported injuries are cases of pneumothoraces. Spontaneous pneumomediastinum and pneu ... Full text Link to item Cite

Left-sided Catamenial Pneumothorax: A Rare Clinical Entity.

Journal Article Cureus · May 2, 2018 Catamenial pneumothorax (CP) is an extremely rare pulmonary pathology seen in women of reproductive age, typically occurring within 72 hours from the onset of menstrual bleeding. Multiple theories have been proposed to explain the etiopathogenesis of CP; h ... Full text Link to item Cite

From Bouveret's Syndrome to Gallstone Ileus: The Journey of a Migrating Stone!

Journal Article Cureus · March 26, 2018 Bouveret's syndrome, first described in 1896, is an unusual cause of gastric outlet obstruction secondary to large gallstone impaction in the proximal duodenum after migration through a cholecystoduodenal fistula. Stone migration has been previously descri ... Full text Link to item Cite

Bouveret's Syndrome: Literature Review.

Journal Article Cureus · March 10, 2018 It was in 1896 that Bouveret's syndrome acquired its name after the French physician Leon Bouveret, who published two case reports in Revue de Medecin. Bouveret's syndrome describes gastric outlet obstruction secondary to an impacted gallstone. The gallsto ... Full text Link to item Cite

A Case of Transudative Chylothorax: A Diagnostic Dilemma.

Journal Article Cureus · February 28, 2018 Chylothorax is a type of pleural effusion characterized by the presence of chyle in the pleural space with triglyceride levels >110 mg/dL or evidence of chylomicrons in pleural fluid. Chylous effusion is typically exudative in nature with lymphocytic predo ... Full text Link to item Cite

Relevance of B-Lines on Lung Ultrasound in Volume Overload and Pulmonary Congestion: Clinical Correlations and Outcomes in Patients on Hemodialysis.

Journal Article Cardiorenal Med · 2018 Featured Publication BACKGROUND: Volume overload in patients on hemodialysis (HD) is an independent risk factor for cardiovascular mortality. B-lines detected on lung ultrasound (BLUS) assess extravascular lung water. This raises interest in its utility for assessing volume st ... Full text Link to item Cite

Fungal Bezoar: A Rare Cause of Ureteral Obstruction.

Journal Article Case reports in infectious diseases · January 2017 A 52-year-old male, with diabetes mellitus and alcoholic liver disease, presented to the Emergency Room for right flank pain of 3 days' duration, associated with dysuria. Physical examination revealed right flank tenderness with fever and hypotension; labo ... Full text Cite

Intercostal Artery Laceration: Rare Complication of Thoracentesis and Role of Ultrasound in Early Detection.

Journal Article Case Rep Pulmonol · 2017 Featured Publication Hemothorax is a rare but potentially fatal postthoracentesis complication. Early clinical signs may be nonspecific resulting in diagnostic delay. A high index of suspicion is vital for early diagnosis and intervention to avoid further bleeding. Following p ... Full text Link to item Cite

Left Lung Torsion: Complication of Lobar Resection for an Early Stage Lung Adenocarcinoma.

Journal Article Case Rep Crit Care · 2016 Featured Publication Lobar torsion is a fatal but fortunately rare occurrence following lung resection. Early clinical signs and radiographic features may be nonspecific resulting in diagnostic delay. A high index of suspicion is vital for early diagnosis and intervention to a ... Full text Link to item Cite