Current Duke Appointments & Affiliations
Assistant Professor in Orthopaedic Surgery
·
2021 - Present
Orthopaedic Surgery,
Clinical Science Departments
Member of Duke Molecular Physiology Institute
·
2019 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Recent Scholarly Works
Feasibility and acceptability of remote ischemic conditioning combined with low-intensity resistance training in older adults with mobility impairments: A randomized controlled pilot trial protocol.
Journal article Exp Gerontol · July 2026 BACKGROUND: Rehabilitation outcomes in older individuals with mobility impairments are often suboptimal due to limited capacity for high-intensity exercise. Remote ischemic conditioning is a low-cost, non-invasive technique that may enhance physiological a ... Full text Link to item CiteCSPG4+ extracellular vesicles carry fibronectin and interleukin-11 and reflect radiographic severity in knee osteoarthritis.
Journal article Osteoarthr Cartil Open · June 2026 OBJECTIVES: To evaluate chondroitin sulfate proteoglycan 4 (CSPG4)+ plasma extracellular vesicles (EVs) as a novel biomarker for knee osteoarthritis (OA) severity across independent study cohorts. METHODS: Radiographic and symptomatic OA severity were eval ... Full text Link to item CiteRYR1+ skeletal muscle-derived extracellular vesicles are exercise responsive and associated with insulin action.
Journal article J Transl Med · May 26, 2026 BACKGROUND: Skeletal muscle is a central regulator of insulin sensitivity and glucose homeostasis. The ryanodine receptor 1 (RYR1) is highly expressed in skeletal muscle and plays a key role in myogenic differentiation. We hypothesize that RYR1+ extracellu ... Full text Link to item CiteRecent Grants
Proteomic Biomarkers Predicting Osteoarthritis Onset and Progression
ResearchCo-Principal Investigator · Awarded by Department of Defense · 2025 - 2027Extracellular Vesicle Analyses to Develop Aging and Resilience Biomarkers
ResearchCo Investigator · Awarded by National Institute on Aging · 2021 - 2026View All Grants