Scholars@Duke
Raven Luo

Selected Publications

UQCRH downregulation promotes Warburg effect in renal cell carcinoma cells

Journal Article Scientific Reports · September 14, 2020 AbstractUbiquinol-cytochrome c reductase hinge protein (UQCRH) is the hinge protein for the multi-subunit complex III of the mitochondrial electron transport chain and is involved in the electron transfer reaction between c ... Full text Cite

Effective combinatorial immunotherapy for penile squamous cell carcinoma

Journal Article Nature Communications · May 1, 2020 AbstractPenile squamous cell carcinoma (PSCC) accounts for over 95% of penile malignancies and causes significant mortality and morbidity in developing countries. Molecular mechanisms and therapies of PSCC are understudied, ... Full text Cite

An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer.

Journal Article Cancer research · July 2018 Advanced prostate cancer displays conspicuous chromosomal instability and rampant copy number aberrations, yet the identity of functional drivers resident in many amplicons remain elusive. Here, we implemented a functional genomics approach to identify new ... Full text Cite

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

Journal Article Nature Communications · April 6, 2016 AbstractCircular RNAs (circRNAs) represent a class of widespread and diverse endogenous RNAs that may regulate gene expression in eukaryotes. However, the regulation and function of human circRNAs remain largely unknown. He ... Full text Cite