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Current Appointments & Affiliations


Recent Publications


Exogenous exposures shape genetic predisposition to lipids, Alzheimer's, and coronary heart disease in the MLXIPL gene locus.

Journal Article Aging · April 2023 Associations of single nucleotide polymorphisms (SNPs) of the MLXIPL lipid gene with Alzheimer's (AD) and coronary heart disease (CHD) and potentially causal mediation effects of their risk factors, high-density lipoprotein cholesterol (HDL-C) and t ... Full text Cite

APOE ɛ4 allele and TOMM40-APOC1 variants jointly contribute to survival to older ages.

Journal Article Aging cell · December 2022 Age-related diseases characteristic of post-reproductive life, aging, and life span are the examples of polygenic non-Mendelian traits with intricate genetic architectures. Polygenicity of these traits implies that multiple variants can impact their risks ... Full text Cite

Genome-wide analysis identified abundant genetic modulators of contributions of the apolipoprotein E alleles to Alzheimer's disease risk.

Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · November 2022 IntroductionThe apolipoprotein E (APOE) ε2 and ε4 alleles have beneficial and adverse impacts on Alzheimer's disease (AD), respectively, with incomplete penetrance, which may be modulated by other genetic variants.MethodsWe examined wheth ... Full text Cite
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Recent Grants


Personalized genetic profiles of risk and resilience in Alzheimer's and vascular diseases

ResearchStatistician · Awarded by National Institute on Aging · 2020 - 2026

ApoE2 and protective molecular signatures in Alzheimer's disease and aging

ResearchStatistician · Awarded by National Institutes of Health · 2018 - 2025

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