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Zhaochen Luo

Research Associate, Senior
Molecular Genetics and Microbiology

Current Duke Appointments & Affiliations


Recent News Items


Published May 1, 2024
New Strategy Could Lead to Universal, Long-Lasting Flu Shot

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Recent Scholarly Works


Vaccination with antigenically complex hemagglutinin mixtures confers broad protection from influenza disease.

Journal article Sci Transl Med · May 2024 Current seasonal influenza virus vaccines induce responses primarily against immunodominant but highly plastic epitopes in the globular head of the hemagglutinin (HA) glycoprotein. Because of viral antigenic drift at these sites, vaccines need to be update ... Full text Link to item Cite

Engineered influenza virions reveal the contributions of non-hemagglutinin structural proteins to vaccine mediated protection.

Journal article J Virol · April 26, 2021 The development of improved and universal anti-influenza vaccines would represent a major advance in the protection of human health. In order to facilitate the development of such vaccines, understanding how viral proteins can contribute to protection from ... Full text Link to item Cite

Dual Role of Toll-Like Receptor 7 in the Pathogenesis of Rabies Virus in a Mouse Model

Journal article Journal of Virology · April 16, 2020 Developing targeted treatment for RABV requires understanding the innate immune response to the virus because early virus clearance is essential for preventing the fatality when the infection has progressed to the CNS. Previous studies have reveale ... Full text Cite
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Recent Grants


Deciphering Immune Responses Induced by Complex Antigen Mixtures

ResearchSenior Research Associate · Awarded by National Institutes of Health · 2026 - 2031

Mechanisms underlying combination adjuvant-driven improvement of influenza vaccine responses

ResearchSr. Res. Assoc. · Awarded by National Institutes of Health · 2026 - 2031

Development of Poultry Specific HPAI Antivirals for Feed-Based Delivery

ResearchSenior Research Associate · Awarded by University of North Carolina - Chapel Hill · 2026 - 2029

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