Overview
survival analysis, dynamic treatment regimes, clinical trials
Current Duke Appointments & Affiliations
Associate Professor of Biostatistics & Bioinformatics
·
2021 - Present
Biostatistics & Bioinformatics, Division of Biostatistics,
Biostatistics & Bioinformatics
Member of the Duke Cancer Institute
·
2010 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Scholarly Works
Win Ratio as an Effect Size Measure Under Non-Proportional Hazards: A Comparison With Difference in Restricted Mean Survival.
Journal article Stat Med · May 2026 When the proportional hazards assumption does not hold, the hazard ratio can misrepresent treatment effects in survival analysis. We evaluate the win ratio, originally proposed for prioritizing multiple outcomes, as an effect size measure for a single surv ... Full text Link to item CiteComparing adaptive treatment strategies in two-stage randomized trials with grouped survival data.
Journal article Lifetime Data Anal · April 2, 2026 Two-stage randomized trials, or the more general sequential multiple assignment randomized trials (SMART), have been increasingly used in studying adaptive treatment strategies for treating chronic diseases or conditions where treatments need to be adjuste ... Full text Link to item CiteA Powerful and Self-Adaptive Weighted Logrank Test.
Journal article Stat Med · February 2026 In a weighted logrank test, such as the Harrington-Fleming test and the Tarone-Ware test, predetermined weights are used to emphasize early, middle, or late differences in survival distributions to maximize the test's power. The optimal weight function und ... Full text Link to item CiteRecent Grants
Integrin alpha-6 drives metabolic adaptation and breast cancer survival in leptomeningeal metastasis
ResearchStatistician · Awarded by National Institutes of Health · 2026 - 2031Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHD
ResearchCo Investigator · Awarded by National Institutes of Health · 2015 - 2031Targeting sphingosine kinase 2 to enhance CAR T-cell therapy efficacy in multiple myeloma
ResearchCo Investigator · Awarded by Cancer Research Institute · 2025 - 2027View All Grants
Education
University of Michigan, Ann Arbor ·
2008
Ph.D.