Overview
My research efforts have been focused on identifying prognostic and therapeutic biomarkers in B-cell lymphoma. My research interests also include investigation of molecular and immune mechanisms underlying the poor clinical outcomes of lymphoma, the pathogenesis and evolution of drug resistant clones, and development of novel therapies for aggressive B-cell lymphoma.
Current Appointments & Affiliations
Assistant Professor in Pathology
·
2021 - Present
Pathology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2019 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Proinflammatory GSDMD activation in live macrophages and DLBCL cells marks cognate interactions and better prognosis.
Journal Article Blood Adv · March 10, 2026 Pyroptosis is a form of programmed cell death characterized by the cleavage of the gasdermin (GSDM) family proteins that form pores in the plasma membrane, cell rupture, and the release of proinflammatory cytokines. In this study, we performed immunohistoc ... Full text Link to item CiteHi-c FFPE sequencing analysis is highly concordant with FISH and detects additional variants informing diagnosis and treatment in diffuse large B-cell lymphoma
Conference Blood · November 3, 2025 AbstractBackground:Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL), accounting for ... Full text CiteMulti-endpoint AI morphology model (MEAM) enhances risk prediction for vascular events and disease progression in MPNs
Conference Blood · November 3, 2025 AbstractINTRODUCTIONThe myeloproliferative neoplasms (MPNs) are clonal haematological disorders that ... Full text CiteRecent Grants
PD-L1 Modifications in Cancer Diagnosis and Treatment
ResearchCo Investigator · Awarded by Baylor College of Medicine · 2025 - 2030Spatially resolved, single cell biomarkers of B cell lymphoma
ResearchCo Investigator · Awarded by Cedars Sinai Medical Center · 2022 - 2026Genetic and Epigenetic Biomarkers for B-cell Lymphoma
ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2025View All Grants
Education
Michigan Technological University ·
2009
Ph.D.