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Zijun Yidan Xu-Monette

Assistant Professor in Pathology
Pathology
905 S LaSalle St, Snyderman GSRB1, Room 1010, Durham, NC 27710
905 S LaSalle St, Snyderman GSRB1, Room 1010, Durham, NC 27710

Overview


My research efforts have been focused on identifying prognostic and therapeutic biomarkers in B-cell lymphoma. My research interests also include investigation of molecular and immune mechanisms underlying the poor clinical outcomes of lymphoma, the pathogenesis and evolution of drug resistant clones, and development of novel therapies for aggressive B-cell lymphoma.

Current Appointments & Affiliations


Assistant Professor in Pathology · 2021 - Present Pathology, Clinical Science Departments
Member of the Duke Cancer Institute · 2019 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


Concurrent or subsequent lymphomatous effusion in large B-cell lymphoma portends a dismal prognosis: A multi-institutional study.

Journal Article Am J Clin Pathol · September 9, 2025 OBJECTIVE: Rare large B-cell lymphomas (LBCLs) present with concurrent or subsequent lymphomatous effusion (solid-effusion LBCL, SE-LBCL), which may have an inferior prognosis compared with their noneffusion counterpart. In addition, the relationship betwe ... Full text Link to item Cite

Prognostic gene expression and microRNA profiling signatures and genetic alterations in primary testicular diffuse large B-cell lymphoma.

Journal Article Blood Cancer J · July 17, 2025 Primary testicular (PT) diffuse large B-cell lymphoma (DLBCL) is a rare and aggressive lymphoma with distinct clinical and molecular characteristics. To identify prognostic biomarkers in PT-DLBCL, in this study we analyzed DNA and RNA samples of PT-DLBCL t ... Full text Link to item Cite

Spatial and single cell mapping of castleman disease reveals key stromal cell types and cytokine pathways.

Journal Article Nat Commun · July 1, 2025 To determine the cellular and molecular basis of Castleman Disease (CD), we analyze the spatial proteome and transcriptome from a discovery (n = 9 cases) and validation (n = 13 cases) cohort of Unicentric CD, idiopathic Multicentric CD, HHV8-associated MCD ... Full text Link to item Cite
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Recent Grants


PD-L1 Modifications in Cancer Diagnosis and Treatment

ResearchCo Investigator · Awarded by Baylor College of Medicine · 2025 - 2030

Spatially resolved, single cell biomarkers of B cell lymphoma

ResearchCo Investigator · Awarded by Cedars Sinai Medical Center · 2022 - 2026

Genetic and Epigenetic Biomarkers for B-cell Lymphoma

ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2025

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Education, Training & Certifications


Michigan Technological University · 2009 Ph.D.