Overview
My research efforts have been focused on identifying prognostic and therapeutic biomarkers in B-cell lymphoma. My research interests also include investigation of molecular and immune mechanisms underlying the poor clinical outcomes of lymphoma, the pathogenesis and evolution of drug resistant clones, and development of novel therapies for aggressive B-cell lymphoma.
Current Appointments & Affiliations
Assistant Professor in Pathology
·
2021 - Present
Pathology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2019 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Proinflammatory GSDMD activation in live macrophages and DLBCL cells marks cognate interactions and better prognosis.
Journal Article Blood Adv · December 4, 2025 Pyroptosis is a form of programmed cell death characterized by the cleavage of gasdermin (GSDM) family proteins that form pores in the plasma membrane, cell rupture, and the release of pro-inflammatory cytokines. In this study, we performed immunohistochem ... Full text Link to item CiteConcurrent or subsequent lymphomatous effusion in large B-cell lymphoma portends a dismal prognosis: A multi-institutional study.
Journal Article Am J Clin Pathol · September 9, 2025 OBJECTIVE: Rare large B-cell lymphomas (LBCLs) present with concurrent or subsequent lymphomatous effusion (solid-effusion LBCL, SE-LBCL), which may have an inferior prognosis compared with their noneffusion counterpart. In addition, the relationship betwe ... Full text Link to item CitePrognostic gene expression and microRNA profiling signatures and genetic alterations in primary testicular diffuse large B-cell lymphoma.
Journal Article Blood Cancer J · July 17, 2025 Primary testicular (PT) diffuse large B-cell lymphoma (DLBCL) is a rare and aggressive lymphoma with distinct clinical and molecular characteristics. To identify prognostic biomarkers in PT-DLBCL, in this study we analyzed DNA and RNA samples of PT-DLBCL t ... Full text Link to item CiteRecent Grants
PD-L1 Modifications in Cancer Diagnosis and Treatment
ResearchCo Investigator · Awarded by Baylor College of Medicine · 2025 - 2030Spatially resolved, single cell biomarkers of B cell lymphoma
ResearchCo Investigator · Awarded by Cedars Sinai Medical Center · 2022 - 2026Genetic and Epigenetic Biomarkers for B-cell Lymphoma
ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2025View All Grants
Education, Training & Certifications
Michigan Technological University ·
2009
Ph.D.