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Snapshot molecular imaging using coded energy-sensitive detection.

Publication ,  Journal Article
Greenberg, JA; Krishnamurthy, K; Brady, D
Published in: Optics express
October 2013

We demonstrate a technique for measuring the range-resolved coherent scatter form factors of different objects from a single snapshot. By illuminating the object with an x-ray pencil beam and placing a coded aperture in front of a linear array of energy-sensitive detector elements, we record the coherently scattered x-rays. This approach yields lateral, range, and momentum transfer resolutions of 1 mm, 5 mm, and 0.2 nm⁻¹, respectively, which is sufficient for the distinguishing a variety of solids and liquids. These results indicate a path toward real-time volumetric molecular imaging for non-destructive examination in a variety of applications, including medical diagnostics, quality inspection, and security detection.

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Published In

Optics express

DOI

EISSN

1094-4087

ISSN

1094-4087

Publication Date

October 2013

Volume

21

Issue

21

Start / End Page

25480 / 25491

Related Subject Headings

  • Refractometry
  • Optics
  • Molecular Imaging
  • Lighting
  • Image Interpretation, Computer-Assisted
  • Image Enhancement
  • Equipment Failure Analysis
  • Equipment Design
  • Algorithms
  • 5102 Atomic, molecular and optical physics
 

Citation

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Greenberg, J. A., Krishnamurthy, K., & Brady, D. (2013). Snapshot molecular imaging using coded energy-sensitive detection. Optics Express, 21(21), 25480–25491. https://doi.org/10.1364/oe.21.025480
Greenberg, Joel A., Kalyani Krishnamurthy, and David Brady. “Snapshot molecular imaging using coded energy-sensitive detection.Optics Express 21, no. 21 (October 2013): 25480–91. https://doi.org/10.1364/oe.21.025480.
Greenberg JA, Krishnamurthy K, Brady D. Snapshot molecular imaging using coded energy-sensitive detection. Optics express. 2013 Oct;21(21):25480–91.
Greenberg, Joel A., et al. “Snapshot molecular imaging using coded energy-sensitive detection.Optics Express, vol. 21, no. 21, Oct. 2013, pp. 25480–91. Epmc, doi:10.1364/oe.21.025480.
Greenberg JA, Krishnamurthy K, Brady D. Snapshot molecular imaging using coded energy-sensitive detection. Optics express. 2013 Oct;21(21):25480–25491.
Journal cover image

Published In

Optics express

DOI

EISSN

1094-4087

ISSN

1094-4087

Publication Date

October 2013

Volume

21

Issue

21

Start / End Page

25480 / 25491

Related Subject Headings

  • Refractometry
  • Optics
  • Molecular Imaging
  • Lighting
  • Image Interpretation, Computer-Assisted
  • Image Enhancement
  • Equipment Failure Analysis
  • Equipment Design
  • Algorithms
  • 5102 Atomic, molecular and optical physics