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Copper-catalyzed electrophilic amination of heteroarenes and arenes by C-H zincation.

Publication ,  Journal Article
McDonald, SL; Hendrick, CE; Wang, Q
Published in: Angewandte Chemie (International ed. in English)
April 2014

Direct amination of heteroarenes and arenes has been achieved in a one-pot CH zincation/copper-catalyzed electrophilic amination procedure. This amination method provides an efficient and rapid approach to access a diverse range of heteroaromatic and aromatic amines including those previously inaccessible using CH amination methods. The mild reaction conditions and good functional-group compatibility demonstrate its great potential for the synthesis of important and complex amines.

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Published In

Angewandte Chemie (International ed. in English)

DOI

EISSN

1521-3773

ISSN

1433-7851

Publication Date

April 2014

Volume

53

Issue

18

Start / End Page

4667 / 4670

Related Subject Headings

  • Organometallic Compounds
  • Organic Chemistry
  • Molecular Structure
  • Hydrocarbons, Aromatic
  • Copper
  • Catalysis
  • Amines
  • Amination
  • Amides
  • 34 Chemical sciences
 

Citation

APA
Chicago
ICMJE
MLA
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McDonald, S. L., Hendrick, C. E., & Wang, Q. (2014). Copper-catalyzed electrophilic amination of heteroarenes and arenes by C-H zincation. Angewandte Chemie (International Ed. in English), 53(18), 4667–4670. https://doi.org/10.1002/anie.201311029
McDonald, Stacey L., Charles E. Hendrick, and Qiu Wang. “Copper-catalyzed electrophilic amination of heteroarenes and arenes by C-H zincation.Angewandte Chemie (International Ed. in English) 53, no. 18 (April 2014): 4667–70. https://doi.org/10.1002/anie.201311029.
McDonald SL, Hendrick CE, Wang Q. Copper-catalyzed electrophilic amination of heteroarenes and arenes by C-H zincation. Angewandte Chemie (International ed in English). 2014 Apr;53(18):4667–70.
McDonald, Stacey L., et al. “Copper-catalyzed electrophilic amination of heteroarenes and arenes by C-H zincation.Angewandte Chemie (International Ed. in English), vol. 53, no. 18, Apr. 2014, pp. 4667–70. Epmc, doi:10.1002/anie.201311029.
McDonald SL, Hendrick CE, Wang Q. Copper-catalyzed electrophilic amination of heteroarenes and arenes by C-H zincation. Angewandte Chemie (International ed in English). 2014 Apr;53(18):4667–4670.
Journal cover image

Published In

Angewandte Chemie (International ed. in English)

DOI

EISSN

1521-3773

ISSN

1433-7851

Publication Date

April 2014

Volume

53

Issue

18

Start / End Page

4667 / 4670

Related Subject Headings

  • Organometallic Compounds
  • Organic Chemistry
  • Molecular Structure
  • Hydrocarbons, Aromatic
  • Copper
  • Catalysis
  • Amines
  • Amination
  • Amides
  • 34 Chemical sciences