Applications of RNA interference high-throughput screening technology in cancer biology and virology.
Publication
, Journal Article
Gao, S; Yang, C; Jiang, S; Xu, X-N; Lu, X; He, Y-W; Cheung, A; Wang, H
Published in: Protein & cell
November 2014
RNA interference (RNAi) is an ancient intra-cellular mechanism that regulates gene expression and cell function. Large-scale gene silencing using RNAi high-throughput screening (HTS) has opened an exciting frontier to systematically study gene function in mammalian cells. This approach enables researchers to identify gene function in a given biological context and will provide considerable novel insight. Here, we review RNAi HTS strategies and applications using case studies in cancer biology and virology.
Published In
Protein & cell
DOI
EISSN
1674-8018
ISSN
1674-800X
Publication Date
November 2014
Volume
5
Issue
11
Start / End Page
805 / 815
Related Subject Headings
- Virus Diseases
- Viral Proteins
- RNA Interference
- Neoplasms
- Molecular Targeted Therapy
- Humans
- Genetic Predisposition to Disease
- Animals
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Gao, S., Yang, C., Jiang, S., Xu, X.-N., Lu, X., He, Y.-W., … Wang, H. (2014). Applications of RNA interference high-throughput screening technology in cancer biology and virology. Protein & Cell, 5(11), 805–815. https://doi.org/10.1007/s13238-014-0076-6
Gao, Shan, Chen Yang, Shan Jiang, Xiao-Ning Xu, Xin Lu, You-Wen He, Annie Cheung, and Hui Wang. “Applications of RNA interference high-throughput screening technology in cancer biology and virology.” Protein & Cell 5, no. 11 (November 2014): 805–15. https://doi.org/10.1007/s13238-014-0076-6.
Gao S, Yang C, Jiang S, Xu X-N, Lu X, He Y-W, et al. Applications of RNA interference high-throughput screening technology in cancer biology and virology. Protein & cell. 2014 Nov;5(11):805–15.
Gao, Shan, et al. “Applications of RNA interference high-throughput screening technology in cancer biology and virology.” Protein & Cell, vol. 5, no. 11, Nov. 2014, pp. 805–15. Epmc, doi:10.1007/s13238-014-0076-6.
Gao S, Yang C, Jiang S, Xu X-N, Lu X, He Y-W, Cheung A, Wang H. Applications of RNA interference high-throughput screening technology in cancer biology and virology. Protein & cell. 2014 Nov;5(11):805–815.
Published In
Protein & cell
DOI
EISSN
1674-8018
ISSN
1674-800X
Publication Date
November 2014
Volume
5
Issue
11
Start / End Page
805 / 815
Related Subject Headings
- Virus Diseases
- Viral Proteins
- RNA Interference
- Neoplasms
- Molecular Targeted Therapy
- Humans
- Genetic Predisposition to Disease
- Animals
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology