Pharmacology and safety of new oral anticoagulants: the challenge of bleeding persists.
Publication
, Other
Levy, JH
Published in: Clin Lab Med
September 2014
New oral anticoagulants (NOACs) are increasingly replacing vitamin K antagonists and older parenteral agents in clinical practice. NOACs offer several advantages compared with standard agents, including rapid onset of action, fixed dosing, and no requirement for routine coagulation monitoring. However, like all anticoagulants, NOACs carry a risk of bleeding. Here, we discuss the pharmacology and safety of NOACs, with particular emphasis on the risks of bleeding associated with NOACs versus standard anticoagulants, and we provide an overview of current bleeding management strategies.
Duke Scholars
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Published In
Clin Lab Med
DOI
EISSN
1557-9832
Publication Date
September 2014
Volume
34
Issue
3
Start / End Page
443 / 452
Location
United States
Related Subject Headings
- beta-Alanine
- Thiophenes
- Rivaroxaban
- Pyridones
- Pyrazoles
- Pathology
- Morpholines
- Humans
- Hemorrhage
- Evidence-Based Medicine
Citation
APA
Chicago
ICMJE
MLA
NLM
Levy, J. H. (2014). Pharmacology and safety of new oral anticoagulants: the challenge of bleeding persists. Clin Lab Med. United States. https://doi.org/10.1016/j.cll.2014.06.003
Levy, Jerrold H. “Pharmacology and safety of new oral anticoagulants: the challenge of bleeding persists.” Clin Lab Med, September 2014. https://doi.org/10.1016/j.cll.2014.06.003.
Levy JH. Pharmacology and safety of new oral anticoagulants: the challenge of bleeding persists. Vol. 34, Clin Lab Med. 2014. p. 443–52.
Levy, Jerrold H. “Pharmacology and safety of new oral anticoagulants: the challenge of bleeding persists.” Clin Lab Med, vol. 34, no. 3, Sept. 2014, pp. 443–52. Pubmed, doi:10.1016/j.cll.2014.06.003.
Levy JH. Pharmacology and safety of new oral anticoagulants: the challenge of bleeding persists. Clin Lab Med. 2014. p. 443–452.
Published In
Clin Lab Med
DOI
EISSN
1557-9832
Publication Date
September 2014
Volume
34
Issue
3
Start / End Page
443 / 452
Location
United States
Related Subject Headings
- beta-Alanine
- Thiophenes
- Rivaroxaban
- Pyridones
- Pyrazoles
- Pathology
- Morpholines
- Humans
- Hemorrhage
- Evidence-Based Medicine