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Identification and preliminary treatment data of xenografts representing tcga-defined subtypes.

Publication ,  Journal Article
Keir, ST; Roskoski, MA; Gasinski, D; Kwatra, MK; Friedman, HS; Bigner, DD
Published in: Neuro Oncol
July 2014

The Cancer Genome Atlas (TCGA) Network recently catalogued recurrent genomic abnormalities in glioblastoma (GBM). This genomic profiling lead to the molecular classification of GBMs into four subtypes: Proneural, Neural, Classical and Mesenchymal. The importance of identifying these subtypes stands to help researchers and clinicians to better understand GBMs with the potential to personalize treatment options and explore different therapeutic approaches that each subtype may require. As such, the development of preclinical xenograft models that represent each TCGA subtype serves to expedite the evaluation of targeted therapeutic strategies for the treatment of GBMs.

Duke Scholars

Published In

Neuro Oncol

DOI

EISSN

1523-5866

Publication Date

July 2014

Volume

16 Suppl 3

Start / End Page

iii35

Location

England

Related Subject Headings

  • Oncology & Carcinogenesis
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
  • 1109 Neurosciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Keir, S. T., Roskoski, M. A., Gasinski, D., Kwatra, M. K., Friedman, H. S., & Bigner, D. D. (2014). Identification and preliminary treatment data of xenografts representing tcga-defined subtypes. Neuro Oncol, 16 Suppl 3, iii35. https://doi.org/10.1093/neuonc/nou208.45
Keir, S. T., M. A. Roskoski, D. Gasinski, M. K. Kwatra, H. S. Friedman, and D. D. Bigner. “Identification and preliminary treatment data of xenografts representing tcga-defined subtypes.Neuro Oncol 16 Suppl 3 (July 2014): iii35. https://doi.org/10.1093/neuonc/nou208.45.
Keir ST, Roskoski MA, Gasinski D, Kwatra MK, Friedman HS, Bigner DD. Identification and preliminary treatment data of xenografts representing tcga-defined subtypes. Neuro Oncol. 2014 Jul;16 Suppl 3:iii35.
Keir, S. T., et al. “Identification and preliminary treatment data of xenografts representing tcga-defined subtypes.Neuro Oncol, vol. 16 Suppl 3, July 2014, p. iii35. Pubmed, doi:10.1093/neuonc/nou208.45.
Keir ST, Roskoski MA, Gasinski D, Kwatra MK, Friedman HS, Bigner DD. Identification and preliminary treatment data of xenografts representing tcga-defined subtypes. Neuro Oncol. 2014 Jul;16 Suppl 3:iii35.
Journal cover image

Published In

Neuro Oncol

DOI

EISSN

1523-5866

Publication Date

July 2014

Volume

16 Suppl 3

Start / End Page

iii35

Location

England

Related Subject Headings

  • Oncology & Carcinogenesis
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
  • 1109 Neurosciences