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Correlation and reproducibility of retinal vascular geometric measurements for stereoscopic retinal images of the same eyes.

Publication ,  Journal Article
Sasongko, MB; Hodgson, LAB; Wong, TY; Kawasaki, R; Cheung, CY; Hsu, W; Lee, ML; Lau, PQF; Mitchell, P; Wang, JJ
Published in: Ophthalmic Epidemiol
October 2012

PURPOSE: To assess the correlation and reproducibility of retinal vascular geometric measurements obtained from two stereo-paired fundus images. METHODS: Thirty stereoscopic pairs of color optic disc-centered photographs from the Blue Mountains Eye Study were analyzed. Side-by-side grading was performed by a single grader, using semi-automated computer software to quantify the following retinal geometric parameters: (1) retinal arteriolar/venular caliber (CRAE/CRVE); (2) arteriole-to-venule ratio (AVR); (3) branching angle; and (4) tortuosity. We used Pearson correlation (r), intra-class correlation coefficient (ICC), and Bland-Altman plots to assess within-pair correlation and reproducibility for each parameter measured. RESULTS: Inter- and intra-grader r and ICC were high (all r > 0.90 and ICC > 0.90), except for branching angle (ICCs between 0.69-0.83). There was no significant difference between within-pair means of all retinal vascular geometric parameters, before and after excluding poor quality images. CRAE, CRVE, AVR, and arteriolar and venular tortuosity showed very high within-pair correlation and agreement (all r > 0.80 and all ICC > 0.90 respectively). Arteriolar and venular branching angles demonstrated moderate within-pair correlation (r = 0.65 and r = 0.62, respectively) and within-pair agreement (ICC = 0.76 and ICC = 0.77, respectively). CONCLUSIONS: Use of computer-assisted software to measure retinal vascular geometric parameters from paired fundus images was highly repeatable and is robust to differences in photographic angles of paired stereo images. Such measurements can be applied to evaluate temporal changes in longitudinal studies.

Duke Scholars

Published In

Ophthalmic Epidemiol

DOI

EISSN

1744-5086

Publication Date

October 2012

Volume

19

Issue

5

Start / End Page

322 / 327

Location

England

Related Subject Headings

  • Venules
  • Retinal Vein
  • Retinal Artery
  • Reproducibility of Results
  • Photography
  • Organ Size
  • Image Processing, Computer-Assisted
  • Humans
  • Epidemiology
  • Arterioles
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sasongko, M. B., Hodgson, L. A. B., Wong, T. Y., Kawasaki, R., Cheung, C. Y., Hsu, W., … Wang, J. J. (2012). Correlation and reproducibility of retinal vascular geometric measurements for stereoscopic retinal images of the same eyes. Ophthalmic Epidemiol, 19(5), 322–327. https://doi.org/10.3109/09286586.2012.702258
Sasongko, Muhammad Bayu, Lauren A. B. Hodgson, Tien Y. Wong, Ryo Kawasaki, Carol Y. Cheung, Wynne Hsu, Mong Li Lee, Peter Q. F. Lau, Paul Mitchell, and Jie Jin Wang. “Correlation and reproducibility of retinal vascular geometric measurements for stereoscopic retinal images of the same eyes.Ophthalmic Epidemiol 19, no. 5 (October 2012): 322–27. https://doi.org/10.3109/09286586.2012.702258.
Sasongko MB, Hodgson LAB, Wong TY, Kawasaki R, Cheung CY, Hsu W, et al. Correlation and reproducibility of retinal vascular geometric measurements for stereoscopic retinal images of the same eyes. Ophthalmic Epidemiol. 2012 Oct;19(5):322–7.
Sasongko, Muhammad Bayu, et al. “Correlation and reproducibility of retinal vascular geometric measurements for stereoscopic retinal images of the same eyes.Ophthalmic Epidemiol, vol. 19, no. 5, Oct. 2012, pp. 322–27. Pubmed, doi:10.3109/09286586.2012.702258.
Sasongko MB, Hodgson LAB, Wong TY, Kawasaki R, Cheung CY, Hsu W, Lee ML, Lau PQF, Mitchell P, Wang JJ. Correlation and reproducibility of retinal vascular geometric measurements for stereoscopic retinal images of the same eyes. Ophthalmic Epidemiol. 2012 Oct;19(5):322–327.

Published In

Ophthalmic Epidemiol

DOI

EISSN

1744-5086

Publication Date

October 2012

Volume

19

Issue

5

Start / End Page

322 / 327

Location

England

Related Subject Headings

  • Venules
  • Retinal Vein
  • Retinal Artery
  • Reproducibility of Results
  • Photography
  • Organ Size
  • Image Processing, Computer-Assisted
  • Humans
  • Epidemiology
  • Arterioles