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A single pipeline embolization device is sufficient for treatment of intracranial aneurysms.

Publication ,  Journal Article
Chalouhi, N; Tjoumakaris, S; Phillips, JLH; Starke, RM; Hasan, D; Wu, C; Zanaty, M; Kung, D; Gonzalez, LF; Rosenwasser, R; Jabbour, P
Published in: AJNR Am J Neuroradiol
August 2014

BACKGROUND AND PURPOSE: The Pipeline Embolization Device has emerged as an important treatment option for intracranial aneurysms. The number of devices needed to treat an aneurysm is uncertain and is the subject of vigorous debate. The purpose of this study was to compare rates of complications, aneurysm occlusion, and outcome in patients treated with a single-versus-multiple Pipeline Embolization Devices. MATERIAL AND METHODS: One hundred seventy-eight patients were treated with the Pipeline Embolization Device at our institution. Patients were divided into 2 groups: a single-device group (n = 126) and a multiple-device group (n = 52). RESULTS: There was no statistically significant difference between the 2 groups with respect to baseline characteristics except for age and aneurysm size (higher with multiple Pipeline Embolization Devices). Complications occurred more frequently with multiple (15%) versus a single device (5%, P = .03). In multivariate analysis, the use of multiple devices independently predicted complications. A similar proportion of patients achieved adequate aneurysm obliteration at follow-up in the single-device (84%) and the multiple-device groups (87%, P = .8). In multivariate analysis, age and follow-up time predicted obliteration. At follow-up, a significantly higher proportion of patients treated with a single device (97%) achieved a favorable outcome compared with those treated with multiple devices (89%, P = .03). In multivariate analysis, there was a strong trend for the use of a single device to predict favorable outcomes (P = .06). CONCLUSIONS: Treatment with a single Pipeline Embolization Device provides similar occlusion rates with less complications and better overall outcomes. These findings suggest that a single Pipeline Embolization Device is sufficient for treatment of most intracranial aneurysms.

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Published In

AJNR Am J Neuroradiol

DOI

EISSN

1936-959X

Publication Date

August 2014

Volume

35

Issue

8

Start / End Page

1562 / 1566

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Nuclear Medicine & Medical Imaging
  • Multivariate Analysis
  • Middle Aged
  • Male
  • Intracranial Aneurysm
  • Humans
  • Female
  • Embolization, Therapeutic
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
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Chalouhi, N., Tjoumakaris, S., Phillips, J. L. H., Starke, R. M., Hasan, D., Wu, C., … Jabbour, P. (2014). A single pipeline embolization device is sufficient for treatment of intracranial aneurysms. AJNR Am J Neuroradiol, 35(8), 1562–1566. https://doi.org/10.3174/ajnr.A3957
Chalouhi, N., S. Tjoumakaris, J. L. H. Phillips, R. M. Starke, D. Hasan, C. Wu, M. Zanaty, et al. “A single pipeline embolization device is sufficient for treatment of intracranial aneurysms.AJNR Am J Neuroradiol 35, no. 8 (August 2014): 1562–66. https://doi.org/10.3174/ajnr.A3957.
Chalouhi N, Tjoumakaris S, Phillips JLH, Starke RM, Hasan D, Wu C, et al. A single pipeline embolization device is sufficient for treatment of intracranial aneurysms. AJNR Am J Neuroradiol. 2014 Aug;35(8):1562–6.
Chalouhi, N., et al. “A single pipeline embolization device is sufficient for treatment of intracranial aneurysms.AJNR Am J Neuroradiol, vol. 35, no. 8, Aug. 2014, pp. 1562–66. Pubmed, doi:10.3174/ajnr.A3957.
Chalouhi N, Tjoumakaris S, Phillips JLH, Starke RM, Hasan D, Wu C, Zanaty M, Kung D, Gonzalez LF, Rosenwasser R, Jabbour P. A single pipeline embolization device is sufficient for treatment of intracranial aneurysms. AJNR Am J Neuroradiol. 2014 Aug;35(8):1562–1566.

Published In

AJNR Am J Neuroradiol

DOI

EISSN

1936-959X

Publication Date

August 2014

Volume

35

Issue

8

Start / End Page

1562 / 1566

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Nuclear Medicine & Medical Imaging
  • Multivariate Analysis
  • Middle Aged
  • Male
  • Intracranial Aneurysm
  • Humans
  • Female
  • Embolization, Therapeutic
  • Adult