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Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: a systematic review and meta-analysis.

Publication ,  Journal Article
Uronis, HE; Ekström, MP; Currow, DC; McCrory, DC; Samsa, GP; Abernethy, AP
Published in: Thorax
May 2015

We searched MEDLINE, EMBASE and the Cochrane Controlled Trials Register to determine whether oxygen relieves dyspnoea in mildly or non-hypoxemic COPD and included 18 randomised controlled trials (431 participants) in the meta-analysis using Cochrane methodology. Oxygen therapy reduced dyspnoea when compared with medical air; standardised mean difference -0.37 (95% CI -0.50 to -0.24; I(2)=14%). In a priori subgroup and sensitivity analyses, dyspnoea was reduced by continuous oxygen during exertion but not short-burst oxygen therapy. Continuous exertional oxygen can relieve dyspnoea in mildly or non-hypoxemic COPD, but evidence from larger clinical trials is needed.

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Published In

Thorax

DOI

EISSN

1468-3296

Publication Date

May 2015

Volume

70

Issue

5

Start / End Page

492 / 494

Location

England

Related Subject Headings

  • Respiratory System
  • Pulmonary Disease, Chronic Obstructive
  • Oxygen Inhalation Therapy
  • Humans
  • Home Care Services
  • Dyspnea
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
 

Citation

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Uronis, H. E., Ekström, M. P., Currow, D. C., McCrory, D. C., Samsa, G. P., & Abernethy, A. P. (2015). Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: a systematic review and meta-analysis. Thorax, 70(5), 492–494. https://doi.org/10.1136/thoraxjnl-2014-205720
Uronis, Hope E., Magnus P. Ekström, David C. Currow, Douglas C. McCrory, Gregory P. Samsa, and Amy P. Abernethy. “Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: a systematic review and meta-analysis.Thorax 70, no. 5 (May 2015): 492–94. https://doi.org/10.1136/thoraxjnl-2014-205720.
Uronis, Hope E., et al. “Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: a systematic review and meta-analysis.Thorax, vol. 70, no. 5, May 2015, pp. 492–94. Pubmed, doi:10.1136/thoraxjnl-2014-205720.

Published In

Thorax

DOI

EISSN

1468-3296

Publication Date

May 2015

Volume

70

Issue

5

Start / End Page

492 / 494

Location

England

Related Subject Headings

  • Respiratory System
  • Pulmonary Disease, Chronic Obstructive
  • Oxygen Inhalation Therapy
  • Humans
  • Home Care Services
  • Dyspnea
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences