Skip to main content
release_alert
Welcome to the new Scholars 3.0! Read about new features and let us know what you think.
cancel
Journal cover image

A practical model for economic evaluation of tissue-engineered therapies.

Publication ,  Journal Article
Tan, T-E; Peh, GSL; Finkelstein, EA; Mehta, JS
Published in: Wiley Interdisciplinary Reviews. Systems Biology and Medicine
March 2015

Tissue-engineered therapies are being developed across virtually all fields of medicine. Some of these therapies are already in clinical use, while others are still in clinical trials or the experimental phase. Most initial studies in the evaluation of new therapies focus on demonstration of clinical efficacy. However, cost considerations or economic viability are just as important. Many tissue-engineered therapies have failed to be impactful because of shortcomings in economic competitiveness, rather than clinical efficacy. Furthermore, such economic viability studies should be performed early in the process of development, before significant investment has been made. Cost-minimization analysis combined with sensitivity analysis is a useful model for the economic evaluation of new tissue-engineered therapies. The analysis can be performed early in the development process, and can provide valuable information to guide further investment and research. The utility of the model is illustrated with the practical real-world example of tissue-engineered constructs for corneal endothelial transplantation.The authors have declared no conflicts of interest for this article.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Wiley Interdisciplinary Reviews. Systems Biology and Medicine

DOI

EISSN

1939-005X

ISSN

1939-5094

Publication Date

March 2015

Volume

7

Issue

2

Start / End Page

91 / 100

Related Subject Headings

  • Tissue Engineering
  • Models, Biological
  • Humans
  • Endothelial Cells
  • Corneal Diseases
  • 1199 Other Medical and Health Sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tan, T.-E., Peh, G. S. L., Finkelstein, E. A., & Mehta, J. S. (2015). A practical model for economic evaluation of tissue-engineered therapies. Wiley Interdisciplinary Reviews. Systems Biology and Medicine, 7(2), 91–100. https://doi.org/10.1002/wsbm.1292
Tan, Tien-En, Gary S. L. Peh, Eric A. Finkelstein, and Jodhbir S. Mehta. “A practical model for economic evaluation of tissue-engineered therapies.Wiley Interdisciplinary Reviews. Systems Biology and Medicine 7, no. 2 (March 2015): 91–100. https://doi.org/10.1002/wsbm.1292.
Tan T-E, Peh GSL, Finkelstein EA, Mehta JS. A practical model for economic evaluation of tissue-engineered therapies. Wiley Interdisciplinary Reviews Systems Biology and Medicine. 2015 Mar;7(2):91–100.
Tan, Tien-En, et al. “A practical model for economic evaluation of tissue-engineered therapies.Wiley Interdisciplinary Reviews. Systems Biology and Medicine, vol. 7, no. 2, Mar. 2015, pp. 91–100. Epmc, doi:10.1002/wsbm.1292.
Tan T-E, Peh GSL, Finkelstein EA, Mehta JS. A practical model for economic evaluation of tissue-engineered therapies. Wiley Interdisciplinary Reviews Systems Biology and Medicine. 2015 Mar;7(2):91–100.
Journal cover image

Published In

Wiley Interdisciplinary Reviews. Systems Biology and Medicine

DOI

EISSN

1939-005X

ISSN

1939-5094

Publication Date

March 2015

Volume

7

Issue

2

Start / End Page

91 / 100

Related Subject Headings

  • Tissue Engineering
  • Models, Biological
  • Humans
  • Endothelial Cells
  • Corneal Diseases
  • 1199 Other Medical and Health Sciences
  • 1103 Clinical Sciences