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Association between tooth loss and cognitive function among 3063 Chinese older adults: a community-based study.

Publication ,  Journal Article
Luo, J; Wu, B; Zhao, Q; Guo, Q; Meng, H; Yu, L; Zheng, L; Hong, Z; Ding, D
Published in: PloS one
January 2015

Oral health has been found to be associated with cognitive function in basic research and epidemiology studies. Most of these studies had no comprehensive clinical diagnosis on cognitive function. This study firstly reported the association between tooth loss and cognitive function among Chinese older population.The study included 3,063 community dwelling older adults aged 60 or above from the Shanghai Aging Study. Number of teeth missing was obtained from self-reporting questionnaire and confirmed by trained interviewers. Participants were diagnosed as "dementia", "mild cognitive impairment (MCI)", or "cognitive normal" by neurologists using DSM-IV and Petersen criteria. Multivariate logistic regression model was applied to examine the association between number of teeth missing and cognitive function.The study participants had an average of 10.2 teeth lost. Individuals with dementia lost 18.7 teeth on average, much higher than those with MCI (11.8) and cognitive normal (9.3) (p<0.001). After adjusted for sex, age, education year, living alone, body mass index, cigarette smoking, alcohol drinking, anxiety, depression, heart disease, hypertension, diabetes, and APOE-ε4, tooth loss of >16 were significantly associated with dementia with an OR of 1.56 (95%CI 1.12-2.18).Having over 16 missing teeth was associated with severe cognitive impairment among Chinese older adults. Poor oral health might be considered as a related factor of neurodegenerative symptom among older Chinese population.

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Published In

PloS one

DOI

EISSN

1932-6203

ISSN

1932-6203

Publication Date

January 2015

Volume

10

Issue

3

Start / End Page

e0120986

Related Subject Headings

  • Tooth Loss
  • Risk Factors
  • Middle Aged
  • Male
  • Humans
  • General Science & Technology
  • Female
  • Dementia
  • Cognitive Dysfunction
  • Cognition
 

Citation

APA
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Luo, J., Wu, B., Zhao, Q., Guo, Q., Meng, H., Yu, L., … Ding, D. (2015). Association between tooth loss and cognitive function among 3063 Chinese older adults: a community-based study. PloS One, 10(3), e0120986. https://doi.org/10.1371/journal.pone.0120986
Luo, Jianfeng, Bei Wu, Qianhua Zhao, Qihao Guo, Haijiao Meng, Lirong Yu, Li Zheng, Zhen Hong, and Ding Ding. “Association between tooth loss and cognitive function among 3063 Chinese older adults: a community-based study.PloS One 10, no. 3 (January 2015): e0120986. https://doi.org/10.1371/journal.pone.0120986.
Luo J, Wu B, Zhao Q, Guo Q, Meng H, Yu L, et al. Association between tooth loss and cognitive function among 3063 Chinese older adults: a community-based study. PloS one. 2015 Jan;10(3):e0120986.
Luo, Jianfeng, et al. “Association between tooth loss and cognitive function among 3063 Chinese older adults: a community-based study.PloS One, vol. 10, no. 3, Jan. 2015, p. e0120986. Epmc, doi:10.1371/journal.pone.0120986.
Luo J, Wu B, Zhao Q, Guo Q, Meng H, Yu L, Zheng L, Hong Z, Ding D. Association between tooth loss and cognitive function among 3063 Chinese older adults: a community-based study. PloS one. 2015 Jan;10(3):e0120986.

Published In

PloS one

DOI

EISSN

1932-6203

ISSN

1932-6203

Publication Date

January 2015

Volume

10

Issue

3

Start / End Page

e0120986

Related Subject Headings

  • Tooth Loss
  • Risk Factors
  • Middle Aged
  • Male
  • Humans
  • General Science & Technology
  • Female
  • Dementia
  • Cognitive Dysfunction
  • Cognition