Skip to main content
Journal cover image

Dietary carbohydrate intake, glycaemic load, glycaemic index and ovarian cancer risk in African-American women.

Publication ,  Journal Article
Qin, B; Moorman, PG; Alberg, AJ; Barnholtz-Sloan, JS; Bondy, M; Cote, ML; Funkhouser, E; Peters, ES; Schwartz, AG; Terry, P; Schildkraut, JM ...
Published in: Br J Nutr
February 28, 2016

Epidemiological evidence regarding the association between carbohydrate intake, glycaemic load (GL) and glycaemic index (GI) and risk of ovarian cancer has been mixed. Little is known about their impact on ovarian cancer risk in African-American women. Associations between carbohydrate quantity and quality and ovarian cancer risk were investigated among 406 cases and 609 controls using data from the African American Cancer Epidemiology Study (AACES). AACES is an ongoing population-based case-control study of ovarian cancer in African-Americans in the USA. Cases were identified through rapid case ascertainment and age- and site-matched controls were identified by random-digit dialling. Dietary information over the year preceding diagnosis or the reference date was obtained using a FFQ. Multivariable logistic regression models were used to estimate odds ratios and 95% CI adjusted for covariates. The OR comparing the highest quartile of total carbohydrate intake and total sugar intake v. the lowest quartile were 1·57 (95% CI 1·08, 2·28; P trend=0·03) and 1·61 (95% CI 1·12, 2·30; P trend<0·01), respectively. A suggestion of an inverse association was found for fibre intake. Higher GL was positively associated with the risk of ovarian cancer (OR 1·18 for each 10 units/4184 kJ (1000 kcal); 95% CI 1·04, 1·33). No associations were observed for starch or GI. Our findings suggest that high intake of total sugars and GL are associated with greater risk of ovarian cancer in African-American women.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Br J Nutr

DOI

EISSN

1475-2662

Publication Date

February 28, 2016

Volume

115

Issue

4

Start / End Page

694 / 702

Location

England

Related Subject Headings

  • Young Adult
  • United States
  • SEER Program
  • Risk Factors
  • Registries
  • Ovarian Neoplasms
  • Nutrition Surveys
  • Nutrition & Dietetics
  • Neoplasms, Glandular and Epithelial
  • Neoplasm Staging
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Qin, B., Moorman, P. G., Alberg, A. J., Barnholtz-Sloan, J. S., Bondy, M., Cote, M. L., … Bandera, E. V. (2016). Dietary carbohydrate intake, glycaemic load, glycaemic index and ovarian cancer risk in African-American women. Br J Nutr, 115(4), 694–702. https://doi.org/10.1017/S0007114515004882
Qin, Bo, Patricia G. Moorman, Anthony J. Alberg, Jill S. Barnholtz-Sloan, Melissa Bondy, Michele L. Cote, Ellen Funkhouser, et al. “Dietary carbohydrate intake, glycaemic load, glycaemic index and ovarian cancer risk in African-American women.Br J Nutr 115, no. 4 (February 28, 2016): 694–702. https://doi.org/10.1017/S0007114515004882.
Qin B, Moorman PG, Alberg AJ, Barnholtz-Sloan JS, Bondy M, Cote ML, et al. Dietary carbohydrate intake, glycaemic load, glycaemic index and ovarian cancer risk in African-American women. Br J Nutr. 2016 Feb 28;115(4):694–702.
Qin, Bo, et al. “Dietary carbohydrate intake, glycaemic load, glycaemic index and ovarian cancer risk in African-American women.Br J Nutr, vol. 115, no. 4, Feb. 2016, pp. 694–702. Pubmed, doi:10.1017/S0007114515004882.
Qin B, Moorman PG, Alberg AJ, Barnholtz-Sloan JS, Bondy M, Cote ML, Funkhouser E, Peters ES, Schwartz AG, Terry P, Schildkraut JM, Bandera EV. Dietary carbohydrate intake, glycaemic load, glycaemic index and ovarian cancer risk in African-American women. Br J Nutr. 2016 Feb 28;115(4):694–702.
Journal cover image

Published In

Br J Nutr

DOI

EISSN

1475-2662

Publication Date

February 28, 2016

Volume

115

Issue

4

Start / End Page

694 / 702

Location

England

Related Subject Headings

  • Young Adult
  • United States
  • SEER Program
  • Risk Factors
  • Registries
  • Ovarian Neoplasms
  • Nutrition Surveys
  • Nutrition & Dietetics
  • Neoplasms, Glandular and Epithelial
  • Neoplasm Staging