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Comparison of intracervical, intrauterine, and intratubal techniques for donor insemination.

Publication ,  Journal Article
Hurd, WW; Randolph, JF; Ansbacher, R; Menge, AC; Ohl, DA; Brown, AN
Published in: Fertil Steril
February 1993

OBJECTIVE: To compare the efficacy of intracervical insemination (ICI), intrauterine insemination (IUI), and a combination of intratubal and intrauterine insemination (ITI/IUI) for donor insemination. DESIGN: Prospective randomized clinical trial. SETTING: The University of Michigan donor insemination program. PATIENTS, PARTICIPANTS: Forty-one women undergoing donor insemination with cryopreserved sperm for either isolated male factor or male factor plus ovulatory dysfunction corrected by clomiphene citrate. INTERVENTION: Each patient was randomly assigned to receive each of the three insemination techniques in consecutive cycles until pregnancy occurred or the patient dropped from the study. MAIN OUTCOME MEASURES: Cycle fecundity rates were compared using the chi 2 test, and cumulative pregnancy rates (PRs) determined by life table analysis were compared using a log-rank test. RESULTS: Cycle fecundity rate was significantly higher for IUI (18.3%) than for ICI (3.9%) or ITI/IUI (7.3%). By life table analysis, the cumulative PR for IUI was significantly higher than for ICI, but the PR for ITI/IUI was not. CONCLUSION: For donor insemination with cryopreserved sperm, IUI increases cycle fecundity compared with ICI. The addition of ITI to IUI, however, interferes with the apparent beneficial effect of IUI alone.

Duke Scholars

Published In

Fertil Steril

ISSN

0015-0282

Publication Date

February 1993

Volume

59

Issue

2

Start / End Page

339 / 342

Location

United States

Related Subject Headings

  • Uterus
  • Spermatozoa
  • Prospective Studies
  • Pregnancy Outcome
  • Pregnancy
  • Obstetrics & Reproductive Medicine
  • Male
  • Insemination, Artificial, Heterologous
  • Humans
  • Female
 

Citation

APA
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ICMJE
MLA
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Hurd, W. W., Randolph, J. F., Ansbacher, R., Menge, A. C., Ohl, D. A., & Brown, A. N. (1993). Comparison of intracervical, intrauterine, and intratubal techniques for donor insemination. Fertil Steril, 59(2), 339–342.
Hurd, W. W., J. F. Randolph, R. Ansbacher, A. C. Menge, D. A. Ohl, and A. N. Brown. “Comparison of intracervical, intrauterine, and intratubal techniques for donor insemination.Fertil Steril 59, no. 2 (February 1993): 339–42.
Hurd WW, Randolph JF, Ansbacher R, Menge AC, Ohl DA, Brown AN. Comparison of intracervical, intrauterine, and intratubal techniques for donor insemination. Fertil Steril. 1993 Feb;59(2):339–42.
Hurd, W. W., et al. “Comparison of intracervical, intrauterine, and intratubal techniques for donor insemination.Fertil Steril, vol. 59, no. 2, Feb. 1993, pp. 339–42.
Hurd WW, Randolph JF, Ansbacher R, Menge AC, Ohl DA, Brown AN. Comparison of intracervical, intrauterine, and intratubal techniques for donor insemination. Fertil Steril. 1993 Feb;59(2):339–342.
Journal cover image

Published In

Fertil Steril

ISSN

0015-0282

Publication Date

February 1993

Volume

59

Issue

2

Start / End Page

339 / 342

Location

United States

Related Subject Headings

  • Uterus
  • Spermatozoa
  • Prospective Studies
  • Pregnancy Outcome
  • Pregnancy
  • Obstetrics & Reproductive Medicine
  • Male
  • Insemination, Artificial, Heterologous
  • Humans
  • Female