False Positive Lyme Disease IgM Immunoblots in Children.
Publication
, Journal Article
Lantos, PM; Lipsett, SC; Nigrovic, LE
Published in: J Pediatr
July 2016
In our cross-sectional sample of 7289 serologic tests for Lyme disease, we identified 167 instances of a positive IgM immunoblot but a negative IgG immunoblot test result. Considering that only 71% (95% CI 64%-78%) of patients had Lyme disease, a positive IgM immunoblot alone should be interpreted with caution to avoid over-diagnosis of Lyme disease.
Duke Scholars
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Published In
J Pediatr
DOI
EISSN
1097-6833
Publication Date
July 2016
Volume
174
Start / End Page
267 / 269.e1
Location
United States
Related Subject Headings
- Sensitivity and Specificity
- Retrospective Studies
- Pediatrics
- Male
- Lyme Disease
- Immunoglobulin M
- Immunoblotting
- Humans
- Female
- False Positive Reactions
Citation
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Chicago
ICMJE
MLA
NLM
Lantos, P. M., Lipsett, S. C., & Nigrovic, L. E. (2016). False Positive Lyme Disease IgM Immunoblots in Children. J Pediatr, 174, 267-269.e1. https://doi.org/10.1016/j.jpeds.2016.04.004
Lantos, Paul M., Susan C. Lipsett, and Lise E. Nigrovic. “False Positive Lyme Disease IgM Immunoblots in Children.” J Pediatr 174 (July 2016): 267-269.e1. https://doi.org/10.1016/j.jpeds.2016.04.004.
Lantos PM, Lipsett SC, Nigrovic LE. False Positive Lyme Disease IgM Immunoblots in Children. J Pediatr. 2016 Jul;174:267-269.e1.
Lantos, Paul M., et al. “False Positive Lyme Disease IgM Immunoblots in Children.” J Pediatr, vol. 174, July 2016, pp. 267-269.e1. Pubmed, doi:10.1016/j.jpeds.2016.04.004.
Lantos PM, Lipsett SC, Nigrovic LE. False Positive Lyme Disease IgM Immunoblots in Children. J Pediatr. 2016 Jul;174:267-269.e1.
Published In
J Pediatr
DOI
EISSN
1097-6833
Publication Date
July 2016
Volume
174
Start / End Page
267 / 269.e1
Location
United States
Related Subject Headings
- Sensitivity and Specificity
- Retrospective Studies
- Pediatrics
- Male
- Lyme Disease
- Immunoglobulin M
- Immunoblotting
- Humans
- Female
- False Positive Reactions