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Patient characteristics as predictors of clinical outcome of distraction in treatment of severe ankle osteoarthritis.

Publication ,  Journal Article
Marijnissen, ACA; Hoekstra, MCL; Pré, BCD; van Roermund, PM; van Melkebeek, J; Amendola, A; Maathuis, P; Lafeber, FPJG; Welsing, PMJ
Published in: J Orthop Res
January 2014

Osteoarthritis (OA) is a slowly progressive joint disease. Joint distraction can be a treatment of choice in case of severe OA. Prediction of failure will facilitate implementation of joint distraction in clinical practice. Patients with severe ankle OA, who underwent joint distraction were included. Survival analysis was performed over 12 years (n = 25 after 12 years). Regression analyses were used to predict failures and clinical benefit at 2 years after joint distraction (n = 111). Survival analysis showed that 44% of the patients failed, 17% within 2 years and 37% within 5 years after joint distraction (n = 48 after 5 years). Survival analysis in subgroups showed that the percentage failure was only different in women (30% after 2 years) versus men (after 11 years still no 30% failure). In the multivariate analyses female gender was predictive for failure 2 years after joint distraction. Gender and functional disability at baseline predicted more pain. Functional disability and pain at baseline were associated with more functional disability. Joint distraction shows a long-term clinical beneficial outcome. However, failure rate is considerable over the years. Female patients have a higher chance of failure during follow-up. Unfortunately, not all potential predictors could be investigated and other clinically significant predictors were not found.

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Published In

J Orthop Res

DOI

EISSN

1554-527X

Publication Date

January 2014

Volume

32

Issue

1

Start / End Page

96 / 101

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Survival Analysis
  • Severity of Illness Index
  • Regression Analysis
  • Recovery of Function
  • Prospective Studies
  • Predictive Value of Tests
  • Osteogenesis, Distraction
  • Osteoarthritis
  • Orthopedics
 

Citation

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Marijnissen, A. C. A., Hoekstra, M. C. L., Pré, B. C. D., van Roermund, P. M., van Melkebeek, J., Amendola, A., … Welsing, P. M. J. (2014). Patient characteristics as predictors of clinical outcome of distraction in treatment of severe ankle osteoarthritis. J Orthop Res, 32(1), 96–101. https://doi.org/10.1002/jor.22475
Marijnissen, A. C. A., M. C. L. Hoekstra, BC du Pré, P. M. van Roermund, J. van Melkebeek, A. Amendola, P. Maathuis, F. P. J. G. Lafeber, and P. M. J. Welsing. “Patient characteristics as predictors of clinical outcome of distraction in treatment of severe ankle osteoarthritis.J Orthop Res 32, no. 1 (January 2014): 96–101. https://doi.org/10.1002/jor.22475.
Marijnissen ACA, Hoekstra MCL, Pré BCD, van Roermund PM, van Melkebeek J, Amendola A, et al. Patient characteristics as predictors of clinical outcome of distraction in treatment of severe ankle osteoarthritis. J Orthop Res. 2014 Jan;32(1):96–101.
Marijnissen, A. C. A., et al. “Patient characteristics as predictors of clinical outcome of distraction in treatment of severe ankle osteoarthritis.J Orthop Res, vol. 32, no. 1, Jan. 2014, pp. 96–101. Pubmed, doi:10.1002/jor.22475.
Marijnissen ACA, Hoekstra MCL, Pré BCD, van Roermund PM, van Melkebeek J, Amendola A, Maathuis P, Lafeber FPJG, Welsing PMJ. Patient characteristics as predictors of clinical outcome of distraction in treatment of severe ankle osteoarthritis. J Orthop Res. 2014 Jan;32(1):96–101.
Journal cover image

Published In

J Orthop Res

DOI

EISSN

1554-527X

Publication Date

January 2014

Volume

32

Issue

1

Start / End Page

96 / 101

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Survival Analysis
  • Severity of Illness Index
  • Regression Analysis
  • Recovery of Function
  • Prospective Studies
  • Predictive Value of Tests
  • Osteogenesis, Distraction
  • Osteoarthritis
  • Orthopedics