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Potential market for new meniscus repair strategies: evaluation of the MOON cohort.

Publication ,  Journal Article
Fetzer, GB; Spindler, KP; Amendola, A; Andrish, JT; Bergfeld, JA; Dunn, WR; Flanigan, DC; Jones, M; Kaeding, CC; Marx, RG; Matava, MJ ...
Published in: J Knee Surg
July 2009

This study aimed to determine the incidence of meniscal tears and describe the tear morphology and selected treatment in patients undergoing anterior cruciate ligament (ACL) reconstruction. We also will discuss the potential market for future tissue engineering aimed at preserving meniscal function. A multicenter cohort of 1014 patients undergoing ACL reconstruction between January 2002 and December 2003 was evaluated. Data on patient demographics, presence of a meniscus tear at time of ACL reconstruction, tear morphology, and meniscal treatment were collected prospectively. Meniscal tears were categorized into 3 potential tissue engineering treatment strategies: all-biologic repair, advanced repair, and scaffold replacement. Of the knees, 36% had medial meniscal tears and 44% had lateral meniscal tears. Longitudinal tears were the most common tear morphology. The most frequent treatment method was partial meniscectomy. Thirty percent of medial meniscal tears and 10% of lateral meniscal tears are eligible for all-biologic repair; 35% of medial meniscal tears and 35% of lateral meniscal tears are eligible for an advanced repair technique; and 35% of medial meniscal tears and 55% of lateral meniscal tears are eligible for scaffold replacement. Although meniscal preservation is generally accepted in the treatment of meniscal tears, most tears in this cohort were not repairable, despite contemporary methods. The results of this cohort will hopefully stimulate and focus future research and development of new tissue engineering strategies for meniscus repair.

Duke Scholars

Published In

J Knee Surg

DOI

ISSN

1538-8506

Publication Date

July 2009

Volume

22

Issue

3

Start / End Page

180 / 186

Location

Germany

Related Subject Headings

  • Young Adult
  • United States
  • Tissue Engineering
  • Tibial Meniscus Injuries
  • Prospective Studies
  • Menisci, Tibial
  • Male
  • Knee Injuries
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
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Fetzer, G. B., Spindler, K. P., Amendola, A., Andrish, J. T., Bergfeld, J. A., Dunn, W. R., … Wright, R. W. (2009). Potential market for new meniscus repair strategies: evaluation of the MOON cohort. J Knee Surg, 22(3), 180–186. https://doi.org/10.1055/s-0030-1247746
Fetzer, Gary B., Kurt P. Spindler, Annunziato Amendola, Jack T. Andrish, John A. Bergfeld, Warren R. Dunn, David C. Flanigan, et al. “Potential market for new meniscus repair strategies: evaluation of the MOON cohort.J Knee Surg 22, no. 3 (July 2009): 180–86. https://doi.org/10.1055/s-0030-1247746.
Fetzer GB, Spindler KP, Amendola A, Andrish JT, Bergfeld JA, Dunn WR, et al. Potential market for new meniscus repair strategies: evaluation of the MOON cohort. J Knee Surg. 2009 Jul;22(3):180–6.
Fetzer, Gary B., et al. “Potential market for new meniscus repair strategies: evaluation of the MOON cohort.J Knee Surg, vol. 22, no. 3, July 2009, pp. 180–86. Pubmed, doi:10.1055/s-0030-1247746.
Fetzer GB, Spindler KP, Amendola A, Andrish JT, Bergfeld JA, Dunn WR, Flanigan DC, Jones M, Kaeding CC, Marx RG, Matava MJ, McCarty EC, Parker RD, Wolcott M, Vidal A, Wolf BR, Wright RW. Potential market for new meniscus repair strategies: evaluation of the MOON cohort. J Knee Surg. 2009 Jul;22(3):180–186.
Journal cover image

Published In

J Knee Surg

DOI

ISSN

1538-8506

Publication Date

July 2009

Volume

22

Issue

3

Start / End Page

180 / 186

Location

Germany

Related Subject Headings

  • Young Adult
  • United States
  • Tissue Engineering
  • Tibial Meniscus Injuries
  • Prospective Studies
  • Menisci, Tibial
  • Male
  • Knee Injuries
  • Humans
  • Female