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Adiposity and blood pressure in South Asian children and adolescents in Karachi.

Publication ,  Journal Article
Almas, A; Jafar, TH
Published in: American journal of hypertension
August 2011

The association of adiposity during childhood with future risk of elevated blood pressure (BP) in South Asian children is not known. We aimed to investigate the relationship between waist circumference (WC) and body mass index (BMI) with BP over a 2-year period, independent of the baseline BP.We analyzed data on children aged 5-14 years who participated in the Control of Blood Pressure and Risk Attenuation (COBRA) trial in Karachi, Pakistan. Separate multivariable models were built for WC and BMI using generalized estimation equations to determine the association between the baseline and changes in adiposity with the primary outcome of increase in systolic BP (SBP) over 2 years of follow-up.We assessed 1,675 children: 51% were boys. At 2 years, 1,278 (76.5%) were available for follow-up. On multivariate analysis, WC at baseline (β (95% confidence interval (CI))) = (0.20 (0.13, 0.29), for each 1 cm increase) and change in WC from baseline to follow-up (0.24 (0.16, 0.34), for each 1 cm increase) were associated with increase in SBP. Similarly BMI at baseline (0.54 (0.33, 0.75) and change in BMI 1.32 (1.06, 1.59), for each 1 kg/m(2) increase) were associated with change in SBP. Categorical expression of adiposity yielded consistent results.Baseline adiposity and increase in adiposity, both, are associated with increase in BP, independent of the baseline level of BP in South Asian children. Both WC and BMI can be used to identify children at high risk of increase in BP.

Duke Scholars

Published In

American journal of hypertension

DOI

EISSN

1941-7225

ISSN

0895-7061

Publication Date

August 2011

Volume

24

Issue

8

Start / End Page

876 / 880

Related Subject Headings

  • Waist Circumference
  • Risk Factors
  • Pakistan
  • Male
  • Humans
  • Follow-Up Studies
  • Female
  • Child, Preschool
  • Child
  • Cardiovascular System & Hematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Almas, A., & Jafar, T. H. (2011). Adiposity and blood pressure in South Asian children and adolescents in Karachi. American Journal of Hypertension, 24(8), 876–880. https://doi.org/10.1038/ajh.2011.67
Almas, Aysha, and Tazeen H. Jafar. “Adiposity and blood pressure in South Asian children and adolescents in Karachi.American Journal of Hypertension 24, no. 8 (August 2011): 876–80. https://doi.org/10.1038/ajh.2011.67.
Almas A, Jafar TH. Adiposity and blood pressure in South Asian children and adolescents in Karachi. American journal of hypertension. 2011 Aug;24(8):876–80.
Almas, Aysha, and Tazeen H. Jafar. “Adiposity and blood pressure in South Asian children and adolescents in Karachi.American Journal of Hypertension, vol. 24, no. 8, Aug. 2011, pp. 876–80. Epmc, doi:10.1038/ajh.2011.67.
Almas A, Jafar TH. Adiposity and blood pressure in South Asian children and adolescents in Karachi. American journal of hypertension. 2011 Aug;24(8):876–880.
Journal cover image

Published In

American journal of hypertension

DOI

EISSN

1941-7225

ISSN

0895-7061

Publication Date

August 2011

Volume

24

Issue

8

Start / End Page

876 / 880

Related Subject Headings

  • Waist Circumference
  • Risk Factors
  • Pakistan
  • Male
  • Humans
  • Follow-Up Studies
  • Female
  • Child, Preschool
  • Child
  • Cardiovascular System & Hematology