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Pathologic changes in highly myopic eyes of young males in Singapore.

Publication ,  Journal Article
Koh, VT; Nah, GK; Chang, L; Yang, AHX; Lin, ST; Ohno-Matsui, K; Wong, TY; Saw, SM
Published in: Ann Acad Med Singap
May 2013

INTRODUCTION: This study describes the pathologic changes in the retina of a group of young Asian subjects with myopia worse than -10 diopters spherical equivalent (SE) refraction. MATERIALS AND METHODS: The study population consists of 20 male subjects undergoing preemployment screening for public service for a 1-year period from 2009 to 2010. A detailed series of visual tests of function, fundus examination and grading, ocular biometry and posterior segment optical coherence tomography were performed for all eyes. RESULTS: A total of 21 eyes with mean SE of -10.88 diopters, [standard deviation (SD) , 1.28 diopters], and mean age of 21.8 years (SD, 1.3 years) were included. Out of 21 eyes, 17 (81.0%) had beta peripapillary atrophy, 10 (47.6%) had clinically detectable optic disc tilt, 1 (4.8%) had positive T-sign and 18 (85.7%) had retinal tessellation, 4 (19.0%) had posterior vitreous detachment and 14 (66.7%) had peripheral retina degeneration. The mean retinal nerve fibre layer (RNFL) thickness was 92.48 mm (SD, 9.99 mm). CONCLUSION: None of the 21 highly myopic eyes had features of myopic retinopathy but most of these young males had clinically visible myopia-associated abnormalities of the optic disc, vitreous and peripheral retina. Generally, these eyes had thinner RNFL. Further longitudinal studies are required to investigate if these eyes will eventually develop complications of pathological myopia.

Duke Scholars

Published In

Ann Acad Med Singap

EISSN

2972-4066

Publication Date

May 2013

Volume

42

Issue

5

Start / End Page

216 / 224

Location

Singapore

Related Subject Headings

  • Young Adult
  • Vitreous Detachment
  • Visual Acuity
  • Vision Tests
  • Tomography, Optical Coherence
  • Singapore
  • Retinal Vessels
  • Retinal Diseases
  • Retinal Degeneration
  • Retina
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Koh, V. T., Nah, G. K., Chang, L., Yang, A. H. X., Lin, S. T., Ohno-Matsui, K., … Saw, S. M. (2013). Pathologic changes in highly myopic eyes of young males in Singapore. Ann Acad Med Singap, 42(5), 216–224.
Koh, Victor Tc, Gerard Km Nah, Lan Chang, Adeline H. X. Yang, Sheng Tong Lin, Kyoko Ohno-Matsui, Tien Yin Wong, and Seang Mei Saw. “Pathologic changes in highly myopic eyes of young males in Singapore.Ann Acad Med Singap 42, no. 5 (May 2013): 216–24.
Koh VT, Nah GK, Chang L, Yang AHX, Lin ST, Ohno-Matsui K, et al. Pathologic changes in highly myopic eyes of young males in Singapore. Ann Acad Med Singap. 2013 May;42(5):216–24.
Koh, Victor Tc, et al. “Pathologic changes in highly myopic eyes of young males in Singapore.Ann Acad Med Singap, vol. 42, no. 5, May 2013, pp. 216–24.
Koh VT, Nah GK, Chang L, Yang AHX, Lin ST, Ohno-Matsui K, Wong TY, Saw SM. Pathologic changes in highly myopic eyes of young males in Singapore. Ann Acad Med Singap. 2013 May;42(5):216–224.

Published In

Ann Acad Med Singap

EISSN

2972-4066

Publication Date

May 2013

Volume

42

Issue

5

Start / End Page

216 / 224

Location

Singapore

Related Subject Headings

  • Young Adult
  • Vitreous Detachment
  • Visual Acuity
  • Vision Tests
  • Tomography, Optical Coherence
  • Singapore
  • Retinal Vessels
  • Retinal Diseases
  • Retinal Degeneration
  • Retina