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Myopia and cognitive dysfunction: the singapore malay eye study.

Publication ,  Journal Article
Ong, S-Y; Ikram, MK; Haaland, BA; Cheng, C-Y; Saw, S-M; Wong, TY; Cheung, CY
Published in: Invest Ophthalmol Vis Sci
January 28, 2013

PURPOSE: To investigate a possible relationship between refractive error and cognitive function. METHODS: This population-based, cross-sectional study included 1032 persons aged 60 to 79 who participated in the Singapore Malay Eye Study. Refraction (sphere, cylinder, and axis) was measured using an autorefractor, and spherical equivalent was defined as sphere plus half negative cylinder. Refractive errors were defined as myopia (spherical equivalent < -0.5), emmetropia (-0.5 diopter [D] ≤ spherical equivalent ≤ 0.5 D), and hyperopia (spherical equivalent > 0.5 D). Visual acuity was measured with a logMAR chart. Cognitive dysfunction, assessed using the Abbreviated Mental Test, was defined based on education-specific cutoff values. RESULTS: Compared with individuals with emmetropia, persons with myopia were almost twice as likely to have cognitive dysfunction (odds ratio 1.82; 95% confidence interval 1.05-3.15), after adjusting for age, sex, body mass index, income, education, and hours of reading and writing per day. Hyperopia was not associated with cognitive dysfunction. The association remained significant after further adjustment for uncorrected refractive errors or best-corrected visual acuity. CONCLUSIONS: Our results provide evidence on a novel association between myopia and cognitive dysfunction.

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Published In

Invest Ophthalmol Vis Sci

DOI

EISSN

1552-5783

Publication Date

January 28, 2013

Volume

54

Issue

1

Start / End Page

799 / 803

Location

United States

Related Subject Headings

  • Visual Acuity
  • Singapore
  • Risk Factors
  • Refraction, Ocular
  • Ophthalmology & Optometry
  • Odds Ratio
  • Myopia
  • Middle Aged
  • Male
  • Macular Degeneration
 

Citation

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Ong, S.-Y., Ikram, M. K., Haaland, B. A., Cheng, C.-Y., Saw, S.-M., Wong, T. Y., & Cheung, C. Y. (2013). Myopia and cognitive dysfunction: the singapore malay eye study. Invest Ophthalmol Vis Sci, 54(1), 799–803. https://doi.org/10.1167/iovs.12-10460
Ong, Shin-Yeu, M Kamran Ikram, Benjamin Adam Haaland, Ching-Yu Cheng, Seang-Mei Saw, Tien Yin Wong, and Carol Y. Cheung. “Myopia and cognitive dysfunction: the singapore malay eye study.Invest Ophthalmol Vis Sci 54, no. 1 (January 28, 2013): 799–803. https://doi.org/10.1167/iovs.12-10460.
Ong S-Y, Ikram MK, Haaland BA, Cheng C-Y, Saw S-M, Wong TY, et al. Myopia and cognitive dysfunction: the singapore malay eye study. Invest Ophthalmol Vis Sci. 2013 Jan 28;54(1):799–803.
Ong, Shin-Yeu, et al. “Myopia and cognitive dysfunction: the singapore malay eye study.Invest Ophthalmol Vis Sci, vol. 54, no. 1, Jan. 2013, pp. 799–803. Pubmed, doi:10.1167/iovs.12-10460.
Ong S-Y, Ikram MK, Haaland BA, Cheng C-Y, Saw S-M, Wong TY, Cheung CY. Myopia and cognitive dysfunction: the singapore malay eye study. Invest Ophthalmol Vis Sci. 2013 Jan 28;54(1):799–803.

Published In

Invest Ophthalmol Vis Sci

DOI

EISSN

1552-5783

Publication Date

January 28, 2013

Volume

54

Issue

1

Start / End Page

799 / 803

Location

United States

Related Subject Headings

  • Visual Acuity
  • Singapore
  • Risk Factors
  • Refraction, Ocular
  • Ophthalmology & Optometry
  • Odds Ratio
  • Myopia
  • Middle Aged
  • Male
  • Macular Degeneration