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Anterior chamber dimensions and posterior corneal arc length in Malay eyes: an anterior segment optical coherence tomography study.

Publication ,  Journal Article
Tan, DKL; Chong, W; Tay, WT; Yuen, LH; He, M; Aung, T; Tan, DTH; Wong, TY; Mehta, JS
Published in: Invest Ophthalmol Vis Sci
July 20, 2012

PURPOSE: We provided normative data of corneal and anterior segment dimensions, and a novel parameter, posterior corneal arc length (PCAL), in an adult Malay population. METHODS: The current analysis is a substudy of the Singapore Malay Eye Study (SiMES), a population-based, cross-sectional study of urban Malay adults aged 40 to 80. Subjects underwent ophthalmic and systemic examination, including imaging with anterior segment optical coherence tomography (AS-OCT). Ocular parameters subsequently were measured with the Zhongshan Assessment Program (ZAP), and included anterior chamber depth (ACD), central corneal thickness (CCT), anterior and posterior corneal curvature (ACC and PCC, respectively), and PCAL, which is a novel parameter defined as the arc-distance of the posterior corneal border between the scleral spurs. Age- and sex-adjusted analyses, and multivariate analyses were performed to determine correlations of PCAL with other ocular and systemic components. RESULTS: We studied 237 subjects, among whom the mean age was 56.6 ± 10.4 years and 50.2% were women. Ocular parameters (mean ± SD) included central ACD 2.78 ± 0.34 mm, CCT 550.23 ± 37.12 mm, ACC 7.43 ± 0.37 mm, PCC 6.75 ± 0.37 mm, and PCAL 13.95 ± 0.51 mm. There was moderate correlation between PCAL and ACD (r = 0.476, P < 0.001), but poor correlation with PCC (r = 0.243, P < 0.001), ACC (r = 0.251, P < 0.001), and systemic parameters, like age, body mass index (BMI), blood pressure, blood glucose levels, hemoglobin A1c (HbA1c), and refractive parameters. Multivariate analysis showed a significant association between PCAL and ACD (P < 0.001), PCC (P < 0.001), and height (P < 0.05). CONCLUSIONS: Our study, to our knowledge, provides the largest baseline anterior segment parameters in an adult Asian Malay population. PCAL correlated moderately with ACD. These data are applicable clinically for assessment and surgical management of patients requiring anterior segment or corneal surgery.

Duke Scholars

Published In

Invest Ophthalmol Vis Sci

DOI

EISSN

1552-5783

Publication Date

July 20, 2012

Volume

53

Issue

8

Start / End Page

4860 / 4867

Location

United States

Related Subject Headings

  • Urban Population
  • Tomography, Optical Coherence
  • Singapore
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Humans
  • Female
  • Cross-Sectional Studies
  • Cornea
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tan, D. K. L., Chong, W., Tay, W. T., Yuen, L. H., He, M., Aung, T., … Mehta, J. S. (2012). Anterior chamber dimensions and posterior corneal arc length in Malay eyes: an anterior segment optical coherence tomography study. Invest Ophthalmol Vis Sci, 53(8), 4860–4867. https://doi.org/10.1167/iovs.12-9787
Tan, Deborah K. L., Wesley Chong, Wan Ting Tay, Leonard H. Yuen, Mingguang He, Tin Aung, Donald T. H. Tan, Tien Yin Wong, and Jodhbir S. Mehta. “Anterior chamber dimensions and posterior corneal arc length in Malay eyes: an anterior segment optical coherence tomography study.Invest Ophthalmol Vis Sci 53, no. 8 (July 20, 2012): 4860–67. https://doi.org/10.1167/iovs.12-9787.
Tan DKL, Chong W, Tay WT, Yuen LH, He M, Aung T, et al. Anterior chamber dimensions and posterior corneal arc length in Malay eyes: an anterior segment optical coherence tomography study. Invest Ophthalmol Vis Sci. 2012 Jul 20;53(8):4860–7.
Tan, Deborah K. L., et al. “Anterior chamber dimensions and posterior corneal arc length in Malay eyes: an anterior segment optical coherence tomography study.Invest Ophthalmol Vis Sci, vol. 53, no. 8, July 2012, pp. 4860–67. Pubmed, doi:10.1167/iovs.12-9787.
Tan DKL, Chong W, Tay WT, Yuen LH, He M, Aung T, Tan DTH, Wong TY, Mehta JS. Anterior chamber dimensions and posterior corneal arc length in Malay eyes: an anterior segment optical coherence tomography study. Invest Ophthalmol Vis Sci. 2012 Jul 20;53(8):4860–4867.

Published In

Invest Ophthalmol Vis Sci

DOI

EISSN

1552-5783

Publication Date

July 20, 2012

Volume

53

Issue

8

Start / End Page

4860 / 4867

Location

United States

Related Subject Headings

  • Urban Population
  • Tomography, Optical Coherence
  • Singapore
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Humans
  • Female
  • Cross-Sectional Studies
  • Cornea