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Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study.

Publication ,  Journal Article
Koh, V; Cheung, CY-L; Zheng, Y; Wong, TY; Wong, W; Aung, T
Published in: Invest Ophthalmol Vis Sci
July 2010

PURPOSE. To describe the association of retinal vascular tortuosity, measured quantitatively, with the neuroretinal rim. METHODS. A population-based, cross-sectional study was conducted in Malay persons aged 40 to 80 years residing in Singapore. Retinal vascular tortuosity was quantified by using a semiautomated, computer-assisted program assessing retinal fundus photographs, according to a standardized protocol. Optic disc measurements including disc area, rim area, and rim-to-disc area (RDA) ratio were obtained with a confocal scanning laser ophthalmoscope. RESULTS. In analyses adjusting for age, sex, spherical equivalent, and retinal vascular caliber, reduced arteriolar and venular tortuosity were associated with a decrease in global RDA ratio (P = 0.006 and P = 0.001, respectively). When compared with the arterioles, retinal venular tortuosity demonstrated a stronger association with RDA ratio. The temporal-inferior region of the neuroretinal rim was most strongly associated with retinal vascular tortuosity. CONCLUSIONS. Straighter retinal vessels were significantly associated with a thinning neuroretinal rim. These findings may provide additional insights into the geometric retinal vascular changes seen in early glaucomatous optic neuropathy.

Duke Scholars

Published In

Invest Ophthalmol Vis Sci

DOI

EISSN

1552-5783

Publication Date

July 2010

Volume

51

Issue

7

Start / End Page

3736 / 3741

Location

United States

Related Subject Headings

  • Singapore
  • Retinal Vessels
  • Photography
  • Optic Nerve Diseases
  • Optic Disk
  • Ophthalmoscopy
  • Ophthalmology & Optometry
  • Nerve Fibers
  • Middle Aged
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Koh, V., Cheung, C.-L., Zheng, Y., Wong, T. Y., Wong, W., & Aung, T. (2010). Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study. Invest Ophthalmol Vis Sci, 51(7), 3736–3741. https://doi.org/10.1167/iovs.09-5008
Koh, Victor, Carol Yim-Lui Cheung, Yingfeng Zheng, Tien Yin Wong, Wanling Wong, and Tin Aung. “Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study.Invest Ophthalmol Vis Sci 51, no. 7 (July 2010): 3736–41. https://doi.org/10.1167/iovs.09-5008.
Koh V, Cheung CY-L, Zheng Y, Wong TY, Wong W, Aung T. Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3736–41.
Koh, Victor, et al. “Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study.Invest Ophthalmol Vis Sci, vol. 51, no. 7, July 2010, pp. 3736–41. Pubmed, doi:10.1167/iovs.09-5008.
Koh V, Cheung CY-L, Zheng Y, Wong TY, Wong W, Aung T. Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3736–3741.

Published In

Invest Ophthalmol Vis Sci

DOI

EISSN

1552-5783

Publication Date

July 2010

Volume

51

Issue

7

Start / End Page

3736 / 3741

Location

United States

Related Subject Headings

  • Singapore
  • Retinal Vessels
  • Photography
  • Optic Nerve Diseases
  • Optic Disk
  • Ophthalmoscopy
  • Ophthalmology & Optometry
  • Nerve Fibers
  • Middle Aged
  • Male