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Psychosocial risk factors and retinal microvascular signs: the multi-ethnic study of atherosclerosis.

Publication ,  Journal Article
Jensen, RA; Shea, S; Ranjit, N; Diez-Roux, A; Wong, TY; Klein, R; Klein, BEK; Cotch, MF; Siscovick, DS
Published in: Am J Epidemiol
March 1, 2010

The association between psychosocial risk factors and retinal microvascular signs was examined in the Multi-Ethnic Study of Atherosclerosis. Subjects were recruited from Baltimore, Maryland; Chicago, Illinois; Forsyth County, North Carolina; Los Angeles County, California; New York, New York; and St. Paul, Minnesota. Levels of depressive symptoms, trait anger, trait anxiety, chronic burdens, emotional support, and cynical distrust were assessed by questionnaire (from July 2000 to July 2002). Digital retinal images (from August 2002 to January 2004) from 6,147 participants were used to evaluate retinopathy and retinal vascular caliber. After controlling for potential confounding factors, the authors found that subjects without access to emotional support (Enriched Social Support Instrument score of <19 vs. > or = 19) had 60% greater odds of retinopathy (odds ratio = 1.6, 95% confidence interval (CI): 1.3, 2.0). Subjects with high Spielberger trait-anxiety scale scores (> or = 22 vs. < or = 14) and subjects with high depressive symptoms (Center for Epidemiology Studies Depression Scale score, > or = 16 vs. <16) were also more likely to have retinopathy (odds ratio = 1.4, 95% CI: 1.1, 1.9 and odds ratio = 1.5, 95% CI: 1.2, 1.9), respectively. In this cross-sectional study, lack of emotional support, increased trait anxiety, and more depressive symptoms were associated with retinopathy signs, independently of other known risk factors.

Duke Scholars

Published In

Am J Epidemiol

DOI

EISSN

1476-6256

Publication Date

March 1, 2010

Volume

171

Issue

5

Start / End Page

522 / 531

Location

United States

Related Subject Headings

  • White People
  • United States
  • Surveys and Questionnaires
  • Risk Factors
  • Retinal Vessels
  • Retinal Diseases
  • Psychology
  • Middle Aged
  • Microvessels
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Jensen, R. A., Shea, S., Ranjit, N., Diez-Roux, A., Wong, T. Y., Klein, R., … Siscovick, D. S. (2010). Psychosocial risk factors and retinal microvascular signs: the multi-ethnic study of atherosclerosis. Am J Epidemiol, 171(5), 522–531. https://doi.org/10.1093/aje/kwp414
Jensen, Richard A., Steven Shea, Nalini Ranjit, Ana Diez-Roux, Tien Y. Wong, Ronald Klein, Barbara E. K. Klein, Mary Frances Cotch, and David S. Siscovick. “Psychosocial risk factors and retinal microvascular signs: the multi-ethnic study of atherosclerosis.Am J Epidemiol 171, no. 5 (March 1, 2010): 522–31. https://doi.org/10.1093/aje/kwp414.
Jensen RA, Shea S, Ranjit N, Diez-Roux A, Wong TY, Klein R, et al. Psychosocial risk factors and retinal microvascular signs: the multi-ethnic study of atherosclerosis. Am J Epidemiol. 2010 Mar 1;171(5):522–31.
Jensen, Richard A., et al. “Psychosocial risk factors and retinal microvascular signs: the multi-ethnic study of atherosclerosis.Am J Epidemiol, vol. 171, no. 5, Mar. 2010, pp. 522–31. Pubmed, doi:10.1093/aje/kwp414.
Jensen RA, Shea S, Ranjit N, Diez-Roux A, Wong TY, Klein R, Klein BEK, Cotch MF, Siscovick DS. Psychosocial risk factors and retinal microvascular signs: the multi-ethnic study of atherosclerosis. Am J Epidemiol. 2010 Mar 1;171(5):522–531.
Journal cover image

Published In

Am J Epidemiol

DOI

EISSN

1476-6256

Publication Date

March 1, 2010

Volume

171

Issue

5

Start / End Page

522 / 531

Location

United States

Related Subject Headings

  • White People
  • United States
  • Surveys and Questionnaires
  • Risk Factors
  • Retinal Vessels
  • Retinal Diseases
  • Psychology
  • Middle Aged
  • Microvessels
  • Male