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Relation of Baseline Renal Dysfunction With Outcomes in Patients Undergoing Popliteal and Infrapopliteal Percutaneous Peripheral Arterial Interventions.

Publication ,  Journal Article
Parvataneni, KC; Piyaskulkaew, C; Szpunar, S; Sharma, T; Patel, V; Patel, S; Davis, T; Lalonde, T; Yamasaki, H; Rosman, HS; Mehta, RH
Published in: Am J Cardiol
July 15, 2016

Renal dysfunction is a major risk factor for peripheral arterial disease (PAD). Infrapopliteal PAD is associated with more co-morbid conditions and worse prognosis than suprapopliteal PAD. Long-term outcomes of patients with renal dysfunction and popliteal or infrapopliteal PAD undergoing peripheral vascular intervention (PVI) are not well described. We retrospectively evaluated long-term outcomes in 726 patients undergoing infrapopliteal PVI categorized into 3 glomerular filtration rate (GFR)-based groups: GFR (≥60 ml/min/1.73 m(2)), GFR (<60 ml/min/1.73 m(2)), and those on dialysis. At mean follow-up of 36 ± 20 months, amputation rates were 3%, 5%, and 11% with mortality rates of 23%, 36%, and 56% in normal renal function, chronic kidney disease (adjusted odds ratio [OR] for amputation 1.75, 95% CI 0.73 to 4.21; adjusted OR for mortality 1.53, 95% CI 1.05 to 2.23, p = 0.028), and dialysis (adjusted OR for amputation 2.43, 95% CI 0.84 to 7.02, p = 0.100; adjusted OR for mortality 4.51, 95% CI 2.46 to 8.26, p <0.0001) groups, respectively. Repeat revascularization was similar in all 3 groups at roughly 25%. In conclusion, chronic kidney disease and dialysis were associated with increased major amputations and mortality in patients who received PVI for popliteal and infrapopliteal PAD.

Duke Scholars

Published In

Am J Cardiol

DOI

EISSN

1879-1913

Publication Date

July 15, 2016

Volume

118

Issue

2

Start / End Page

298 / 302

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Risk Factors
  • Retrospective Studies
  • Renal Insufficiency, Chronic
  • Renal Dialysis
  • Popliteal Artery
  • Peripheral Arterial Disease
  • Odds Ratio
  • Male
  • Kidney Failure, Chronic
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Parvataneni, K. C., Piyaskulkaew, C., Szpunar, S., Sharma, T., Patel, V., Patel, S., … Mehta, R. H. (2016). Relation of Baseline Renal Dysfunction With Outcomes in Patients Undergoing Popliteal and Infrapopliteal Percutaneous Peripheral Arterial Interventions. Am J Cardiol, 118(2), 298–302. https://doi.org/10.1016/j.amjcard.2016.04.029
Parvataneni, Kesav C., Chatchawan Piyaskulkaew, Susan Szpunar, Tarun Sharma, Vishal Patel, Saurabhkumar Patel, Thomas Davis, et al. “Relation of Baseline Renal Dysfunction With Outcomes in Patients Undergoing Popliteal and Infrapopliteal Percutaneous Peripheral Arterial Interventions.Am J Cardiol 118, no. 2 (July 15, 2016): 298–302. https://doi.org/10.1016/j.amjcard.2016.04.029.
Parvataneni KC, Piyaskulkaew C, Szpunar S, Sharma T, Patel V, Patel S, et al. Relation of Baseline Renal Dysfunction With Outcomes in Patients Undergoing Popliteal and Infrapopliteal Percutaneous Peripheral Arterial Interventions. Am J Cardiol. 2016 Jul 15;118(2):298–302.
Parvataneni, Kesav C., et al. “Relation of Baseline Renal Dysfunction With Outcomes in Patients Undergoing Popliteal and Infrapopliteal Percutaneous Peripheral Arterial Interventions.Am J Cardiol, vol. 118, no. 2, July 2016, pp. 298–302. Pubmed, doi:10.1016/j.amjcard.2016.04.029.
Parvataneni KC, Piyaskulkaew C, Szpunar S, Sharma T, Patel V, Patel S, Davis T, Lalonde T, Yamasaki H, Rosman HS, Mehta RH. Relation of Baseline Renal Dysfunction With Outcomes in Patients Undergoing Popliteal and Infrapopliteal Percutaneous Peripheral Arterial Interventions. Am J Cardiol. 2016 Jul 15;118(2):298–302.
Journal cover image

Published In

Am J Cardiol

DOI

EISSN

1879-1913

Publication Date

July 15, 2016

Volume

118

Issue

2

Start / End Page

298 / 302

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Risk Factors
  • Retrospective Studies
  • Renal Insufficiency, Chronic
  • Renal Dialysis
  • Popliteal Artery
  • Peripheral Arterial Disease
  • Odds Ratio
  • Male
  • Kidney Failure, Chronic