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The patient perspective on absence of disease activity in rheumatoid arthritis: a survey to identify key domains of patient-perceived remission.

Publication ,  Journal Article
van Tuyl, LHD; Sadlonova, M; Hewlett, S; Davis, B; Flurey, C; Goel, N; Gossec, L; Heegaard Brahe, C; Hill, CL; Hoogland, W; Kirwan, J ...
Published in: Ann Rheum Dis
May 2017

BACKGROUND: Guidelines suggest treatment in rheumatoid arthritis (RA) to target remission, in close consultation with the patient. Our recent qualitative study of the patients' perspective on remission in RA identified 26 domains. The current study aimed to identify a short list of the most important aspects to inform future research. METHODS: Patients with RA from the Netherlands, the UK, Austria, Denmark, France and the USA completed a survey that contained all domains identified in our qualitative study. They rated domains for importance ('not important', 'important' or 'essential' to characterise a period of remission) and if important or essential, whether this domain needs to be 'less', 'almost gone' or 'gone' to reflect remission. Respondents were also asked to determine their personal top 3 most important/essential domains. Frequency of specific domains in the top 3 was calculated, and domains were sorted on the percentage of patients that evaluated a particular domain as 'essential'. RESULTS: Of 274 respondents, 75% were female, mean (SD) age 57(13) years, disease duration 12(9) years. The top 3 were as follows: pain (67%), fatigue (33%) and independence (19%); domains most frequently rated as 'essential' were as follows: pain (60%), being mobile (52%), physical function (51%), being independent (47%) and fatigue (41%). Pain needed to be less (13%), almost gone (42%) or gone (45%) to reflect remission. Similar patterns were seen for fatigue, independence, mobility and physical functioning. CONCLUSION: Patients identified pain, fatigue and independence as the most important domains of RA disease activity that need to be improved to reflect remission.

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Published In

Ann Rheum Dis

DOI

EISSN

1468-2060

Publication Date

May 2017

Volume

76

Issue

5

Start / End Page

855 / 861

Location

England

Related Subject Headings

  • Surveys and Questionnaires
  • Severity of Illness Index
  • Remission Induction
  • Qualitative Research
  • Patient Outcome Assessment
  • Pain
  • Middle Aged
  • Male
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
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van Tuyl, L. H. D., Sadlonova, M., Hewlett, S., Davis, B., Flurey, C., Goel, N., … Boers, M. (2017). The patient perspective on absence of disease activity in rheumatoid arthritis: a survey to identify key domains of patient-perceived remission. Ann Rheum Dis, 76(5), 855–861. https://doi.org/10.1136/annrheumdis-2016-209835
Tuyl, Lilian H. D. van, Martina Sadlonova, Sarah Hewlett, Bev Davis, Caroline Flurey, Niti Goel, Laure Gossec, et al. “The patient perspective on absence of disease activity in rheumatoid arthritis: a survey to identify key domains of patient-perceived remission.Ann Rheum Dis 76, no. 5 (May 2017): 855–61. https://doi.org/10.1136/annrheumdis-2016-209835.
van Tuyl LHD, Sadlonova M, Hewlett S, Davis B, Flurey C, Goel N, et al. The patient perspective on absence of disease activity in rheumatoid arthritis: a survey to identify key domains of patient-perceived remission. Ann Rheum Dis. 2017 May;76(5):855–61.
van Tuyl, Lilian H. D., et al. “The patient perspective on absence of disease activity in rheumatoid arthritis: a survey to identify key domains of patient-perceived remission.Ann Rheum Dis, vol. 76, no. 5, May 2017, pp. 855–61. Pubmed, doi:10.1136/annrheumdis-2016-209835.
van Tuyl LHD, Sadlonova M, Hewlett S, Davis B, Flurey C, Goel N, Gossec L, Heegaard Brahe C, Hill CL, Hoogland W, Kirwan J, Hetland ML, van Schaardenburg D, Smolen JS, Stamm T, Voshaar M, Wells GA, Boers M. The patient perspective on absence of disease activity in rheumatoid arthritis: a survey to identify key domains of patient-perceived remission. Ann Rheum Dis. 2017 May;76(5):855–861.

Published In

Ann Rheum Dis

DOI

EISSN

1468-2060

Publication Date

May 2017

Volume

76

Issue

5

Start / End Page

855 / 861

Location

England

Related Subject Headings

  • Surveys and Questionnaires
  • Severity of Illness Index
  • Remission Induction
  • Qualitative Research
  • Patient Outcome Assessment
  • Pain
  • Middle Aged
  • Male
  • Humans
  • Female