Scholars@Duke

On the estimation of variance components in stability analysis

Publication ,  Journal Article
Chow, SC; Wang, SG
Published in: Communications in Statistics - Theory and Methods
January 1, 1994
Published version (DOI)

Chow and Shao (1989, 1991) indicated that the presence of batch-to-batch variation has an impact on the determination of drug shelf-life in stability studies. In this paper, we propose two unbiased estmators for batch-to-batch variation. The proposed estimators are compared in terms of their corresponding variances. An example concerning a stability study is discussed to illustrate the use of the proposed estimators. © 1994, Taylor & Francis Group, LLC. All rights reserved.

Duke Scholars

Shein-Chung Chow
Author Shein-Chung Chow Biostatistics & Bioinformatics, Division of Biostatistics

Published In

Communications in Statistics - Theory and Methods

DOI

10.1080/03610929408831254

EISSN

1532-415X

ISSN

0361-0926

Publication Date

January 1, 1994

Volume

23

Issue

1

Start / End Page

289 / 303

Related Subject Headings

  • Statistics & Probability
  • 4905 Statistics
  • 0199 Other Mathematical Sciences
  • 0104 Statistics
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chow, S. C., & Wang, S. G. (1994). On the estimation of variance components in stability analysis. Communications in Statistics - Theory and Methods, 23(1), 289–303. https://doi.org/10.1080/03610929408831254
Chow, S. C., and S. G. Wang. “On the estimation of variance components in stability analysis.” Communications in Statistics - Theory and Methods 23, no. 1 (January 1, 1994): 289–303. https://doi.org/10.1080/03610929408831254.
Chow SC, Wang SG. On the estimation of variance components in stability analysis. Communications in Statistics - Theory and Methods. 1994 Jan 1;23(1):289–303.
Chow, S. C., and S. G. Wang. “On the estimation of variance components in stability analysis.” Communications in Statistics - Theory and Methods, vol. 23, no. 1, Jan. 1994, pp. 289–303. Scopus, doi:10.1080/03610929408831254.
Chow SC, Wang SG. On the estimation of variance components in stability analysis. Communications in Statistics - Theory and Methods. 1994 Jan 1;23(1):289–303.

Published In

Communications in Statistics - Theory and Methods

DOI

10.1080/03610929408831254

EISSN

1532-415X

ISSN

0361-0926

Publication Date

January 1, 1994

Volume

23

Issue

1

Start / End Page

289 / 303

Related Subject Headings

  • Statistics & Probability
  • 4905 Statistics
  • 0199 Other Mathematical Sciences
  • 0104 Statistics