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Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture).

Publication ,  Journal Article
Modrich, P
Published in: Angew Chem Int Ed Engl
July 18, 2016

DNA molecules are not completely stable, they are subject to chemical or photochemical damage and errors that occur during DNA replication resulting in mismatched base pairs. Through mechanistic studies Paul Modrich showed how replication errors are corrected by strand-directed mismatch repair in Escherichia coli and human cells.

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Published In

Angew Chem Int Ed Engl

DOI

EISSN

1521-3773

Publication Date

July 18, 2016

Volume

55

Issue

30

Start / End Page

8490 / 8501

Location

Germany

Related Subject Headings

  • Organic Chemistry
  • MutS DNA Mismatch-Binding Protein
  • MutL Proteins
  • MutL Protein Homolog 1
  • Humans
  • Escherichia coli Proteins
  • Escherichia coli
  • DNA Mismatch Repair
  • DNA Methylation
  • DNA Helicases
 

Citation

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Modrich, P. (2016). Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture). Angew Chem Int Ed Engl, 55(30), 8490–8501. https://doi.org/10.1002/anie.201601412
Modrich, Paul. “Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture).Angew Chem Int Ed Engl 55, no. 30 (July 18, 2016): 8490–8501. https://doi.org/10.1002/anie.201601412.
Modrich P. Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture). Angew Chem Int Ed Engl. 2016 Jul 18;55(30):8490–501.
Modrich, Paul. “Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture).Angew Chem Int Ed Engl, vol. 55, no. 30, July 2016, pp. 8490–501. Pubmed, doi:10.1002/anie.201601412.
Modrich P. Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture). Angew Chem Int Ed Engl. 2016 Jul 18;55(30):8490–8501.
Journal cover image

Published In

Angew Chem Int Ed Engl

DOI

EISSN

1521-3773

Publication Date

July 18, 2016

Volume

55

Issue

30

Start / End Page

8490 / 8501

Location

Germany

Related Subject Headings

  • Organic Chemistry
  • MutS DNA Mismatch-Binding Protein
  • MutL Proteins
  • MutL Protein Homolog 1
  • Humans
  • Escherichia coli Proteins
  • Escherichia coli
  • DNA Mismatch Repair
  • DNA Methylation
  • DNA Helicases