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Inflammatory mechanisms.
Publication
, Journal Article
Farzaneh-Far, A; Rudd, J; Weissberg, PL
Published in: Br Med Bull
2001
Traditional concepts of the pathogenesis of acute coronary syndromes have changed over the last few years. In particular it has been demonstrated that high-risk lesions are not necessarily angiographically severe. Rather, unstable high risk lesions are the ones composed of large lipid cores and thin fibrous caps. It is now widely accepted that plaque instability is related to the development of inflammation within the intima. A consequence of this is that stabilization of lesions provides a new therapeutic target. Furthermore, there is growing evidence that statins may stabilize lesions by altering the inflammatory response. A brief overview of these developments and their impact on clinical practice is presented.
Duke Scholars
Published In
Br Med Bull
DOI
ISSN
0007-1420
Publication Date
2001
Volume
59
Start / End Page
55 / 68
Location
England
Related Subject Headings
- Vasculitis
- Risk Assessment
- Oxidative Stress
- Muscle, Smooth, Vascular
- Magnetic Resonance Imaging
- Humans
- General & Internal Medicine
- Endothelium, Vascular
- Coronary Disease
- Coronary Artery Disease
Citation
APA
Chicago
ICMJE
MLA
NLM
Farzaneh-Far, A., Rudd, J., & Weissberg, P. L. (2001). Inflammatory mechanisms. Br Med Bull, 59, 55–68. https://doi.org/10.1093/bmb/59.1.55
Farzaneh-Far, A., J. Rudd, and P. L. Weissberg. “Inflammatory mechanisms.” Br Med Bull 59 (2001): 55–68. https://doi.org/10.1093/bmb/59.1.55.
Farzaneh-Far A, Rudd J, Weissberg PL. Inflammatory mechanisms. Br Med Bull. 2001;59:55–68.
Farzaneh-Far, A., et al. “Inflammatory mechanisms.” Br Med Bull, vol. 59, 2001, pp. 55–68. Pubmed, doi:10.1093/bmb/59.1.55.
Farzaneh-Far A, Rudd J, Weissberg PL. Inflammatory mechanisms. Br Med Bull. 2001;59:55–68.
![Journal cover image](https://secure.syndetics.com/index.aspx?isbn=/lc.gif&issn=0007-1420&client=dukeuniv)
Published In
Br Med Bull
DOI
ISSN
0007-1420
Publication Date
2001
Volume
59
Start / End Page
55 / 68
Location
England
Related Subject Headings
- Vasculitis
- Risk Assessment
- Oxidative Stress
- Muscle, Smooth, Vascular
- Magnetic Resonance Imaging
- Humans
- General & Internal Medicine
- Endothelium, Vascular
- Coronary Disease
- Coronary Artery Disease