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Health Equity Considerations for Developing and Reporting Patient-reported Outcomes in Clinical Trials: A Report from the OMERACT Equity Special Interest Group.

Publication ,  Journal Article
Petkovic, J; Barton, JL; Flurey, C; Goel, N; Bartels, CM; Barnabe, C; de Wit, MPT; Lyddiatt, A; Lacaille, D; Welch, V; Boonen, A; Shea, B ...
Published in: J Rheumatol
November 2017

OBJECTIVE: Despite advances integrating patient-centered outcomes into rheumatologic studies, concerns remain regarding their representativeness across diverse patient groups and how this affects equity. The Outcome Measures in Rheumatology (OMERACT) Equity Working Group aims to determine whether and how to address equity issues within the core outcome sets of domains and instruments. METHODS: We surveyed current and previous OMERACT meeting attendees and members of the Campbell and Cochrane Equity Group regarding whether to address equity issues within the OMERACT Filter 2.0 Core Outcome Sets and how to assess the appropriateness of domains, instruments, and measurement properties among diverse patients. At OMERACT 2016, results of the survey and a narrative review of differential psychosocial effects of rheumatoid arthritis (i.e., on men) were presented to stimulate discussion and develop a research agenda. RESULTS: We proposed 6 moments for which an equity lens could be added to the development, selection, or testing of patient-reported outcome measures (PROM): (1) recruitment, (2) domain selection, (3) feasibility in diverse settings, (4) instrument validity, (5) thresholds of meaning, and (6) consideration of statistical power of subgroup analyses for outcome reporting. CONCLUSION: There is a need to (1) conduct a systematic review to assess how equity and population characteristics have been considered in PROM development and whether these differences influence the ranking of importance of outcome domains or a patient's response to questionnaire items, and (2) conduct the same survey described above with patients representing groups experiencing health inequities.

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Published In

J Rheumatol

DOI

EISSN

1499-2752

Publication Date

November 2017

Volume

44

Issue

11

Start / End Page

1727 / 1733

Location

Canada

Related Subject Headings

  • Rheumatology
  • Patient Reported Outcome Measures
  • Outcome Assessment, Health Care
  • Humans
  • Health Equity
  • Clinical Trials as Topic
  • Arthritis & Rheumatology
  • Arthritis
  • 3204 Immunology
  • 3202 Clinical sciences
 

Citation

APA
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Petkovic, J., Barton, J. L., Flurey, C., Goel, N., Bartels, C. M., Barnabe, C., … Tugwell, P. S. (2017). Health Equity Considerations for Developing and Reporting Patient-reported Outcomes in Clinical Trials: A Report from the OMERACT Equity Special Interest Group. J Rheumatol, 44(11), 1727–1733. https://doi.org/10.3899/jrheum.160975
Petkovic, Jennifer, Jennifer L. Barton, Caroline Flurey, Niti Goel, Christie M. Bartels, Cheryl Barnabe, Maarten P. T. de Wit, et al. “Health Equity Considerations for Developing and Reporting Patient-reported Outcomes in Clinical Trials: A Report from the OMERACT Equity Special Interest Group.J Rheumatol 44, no. 11 (November 2017): 1727–33. https://doi.org/10.3899/jrheum.160975.
Petkovic J, Barton JL, Flurey C, Goel N, Bartels CM, Barnabe C, et al. Health Equity Considerations for Developing and Reporting Patient-reported Outcomes in Clinical Trials: A Report from the OMERACT Equity Special Interest Group. J Rheumatol. 2017 Nov;44(11):1727–33.
Petkovic, Jennifer, et al. “Health Equity Considerations for Developing and Reporting Patient-reported Outcomes in Clinical Trials: A Report from the OMERACT Equity Special Interest Group.J Rheumatol, vol. 44, no. 11, Nov. 2017, pp. 1727–33. Pubmed, doi:10.3899/jrheum.160975.
Petkovic J, Barton JL, Flurey C, Goel N, Bartels CM, Barnabe C, de Wit MPT, Lyddiatt A, Lacaille D, Welch V, Boonen A, Shea B, Christensen R, Maxwell LJ, Campbell W, Jull J, Toupin-April K, Singh JA, Goldsmith CH, Sreih AG, Pohl C, Hofstetter C, Beaton DE, Buchbinder R, Guillemin F, Tugwell PS. Health Equity Considerations for Developing and Reporting Patient-reported Outcomes in Clinical Trials: A Report from the OMERACT Equity Special Interest Group. J Rheumatol. 2017 Nov;44(11):1727–1733.

Published In

J Rheumatol

DOI

EISSN

1499-2752

Publication Date

November 2017

Volume

44

Issue

11

Start / End Page

1727 / 1733

Location

Canada

Related Subject Headings

  • Rheumatology
  • Patient Reported Outcome Measures
  • Outcome Assessment, Health Care
  • Humans
  • Health Equity
  • Clinical Trials as Topic
  • Arthritis & Rheumatology
  • Arthritis
  • 3204 Immunology
  • 3202 Clinical sciences