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Vasculitis and Pregnancy.

Publication ,  Journal Article
Machen, L; Clowse, MEB
Published in: Rheum Dis Clin North Am
May 2017

Vasculitis is more often a disease of women beyond their reproductive years, leaving the challenges of pregnancy management difficult to study. Pregnancy complications, including pregnancy loss and preterm birth, are higher among women with all forms of vasculitis. It seems that controlling the disease before pregnancy may improve the chances of pregnancy success. Many medications used for vasculitis are considered low risk in pregnancy, including prednisone, colchicine, azathioprine, and tumor necrosis factor inhibitors. Cyclophosphamide, methotrexate, and mycophenolate mofetil should be avoided in pregnancy. Controlling disease with low-risk medications may allow women with vasculitis to have the pregnancies they desire.

Duke Scholars

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Published In

Rheum Dis Clin North Am

DOI

EISSN

1558-3163

Publication Date

May 2017

Volume

43

Issue

2

Start / End Page

239 / 247

Location

United States

Related Subject Headings

  • Vasculitis
  • Tumor Necrosis Factor-alpha
  • Takayasu Arteritis
  • Pregnancy Complications
  • Pregnancy
  • Mycophenolic Acid
  • Methotrexate
  • Immunosuppressive Agents
  • Humans
  • Glucocorticoids
 

Citation

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Machen, L., & Clowse, M. E. B. (2017). Vasculitis and Pregnancy. Rheum Dis Clin North Am, 43(2), 239–247. https://doi.org/10.1016/j.rdc.2016.12.005
Machen, Leah, and Megan E. B. Clowse. “Vasculitis and Pregnancy.Rheum Dis Clin North Am 43, no. 2 (May 2017): 239–47. https://doi.org/10.1016/j.rdc.2016.12.005.
Machen L, Clowse MEB. Vasculitis and Pregnancy. Rheum Dis Clin North Am. 2017 May;43(2):239–47.
Machen, Leah, and Megan E. B. Clowse. “Vasculitis and Pregnancy.Rheum Dis Clin North Am, vol. 43, no. 2, May 2017, pp. 239–47. Pubmed, doi:10.1016/j.rdc.2016.12.005.
Machen L, Clowse MEB. Vasculitis and Pregnancy. Rheum Dis Clin North Am. 2017 May;43(2):239–247.
Journal cover image

Published In

Rheum Dis Clin North Am

DOI

EISSN

1558-3163

Publication Date

May 2017

Volume

43

Issue

2

Start / End Page

239 / 247

Location

United States

Related Subject Headings

  • Vasculitis
  • Tumor Necrosis Factor-alpha
  • Takayasu Arteritis
  • Pregnancy Complications
  • Pregnancy
  • Mycophenolic Acid
  • Methotrexate
  • Immunosuppressive Agents
  • Humans
  • Glucocorticoids