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Dietary Quality and Ovarian Cancer Risk in African-American Women.

Publication ,  Journal Article
Qin, B; Moorman, PG; Kelemen, LE; Alberg, AJ; Barnholtz-Sloan, JS; Bondy, M; Cote, ML; Funkhouser, E; Peters, ES; Schwartz, AG; Terry, P ...
Published in: Am J Epidemiol
June 15, 2017

This study evaluated 3 index-based dietary patterns-Healthy Eating Index (HEI)-2005, HEI-2010, and Alternate Healthy Eating Index (AHEI)-2010-in relation to ovarian cancer risk in African-American women. The study was conducted among 415 ovarian cancer cases and 629 age- and site-matched controls of African-American descent recruited from the population-based African American Cancer Epidemiology Study. Multivariable unconditional logistic regression models were used to estimate odds ratios and 95% confidence intervals between quartiles of dietary quality indices and ovarian cancer risk, adjusting for potential confounders. We found that higher AHEI-2010 scores, but not HEI-2005 or HEI-2010 scores, were associated with lower risk of ovarian cancer (comparing the highest quartile (4th) vs. lowest (1st), odds ratio (OR) = 0.66, 95% confidence interval (CI): 0.45, 0.98; P for trend = 0.05). When stratified by menopausal status, no noteworthy associations were observed among premenopausal women. However, among postmenopausal women, greater adherence to HEI-2010 (quartile 4 vs. quartile 1, OR = 0.57, 95% CI: 0.36, 0.92; P for trend = 0.03) and AHEI-2010 (quartile 4 vs. quartile 1, OR = 0.49, 95% CI: 0.31, 0.78; P for trend = 0.01) were inversely associated with ovarian cancer. Our findings indicate that adherence to an overall healthy dietary pattern may reduce ovarian cancer risk in African-American women, and particularly among postmenopausal African-American women.

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Published In

Am J Epidemiol

DOI

EISSN

1476-6256

Publication Date

June 15, 2017

Volume

185

Issue

12

Start / End Page

1281 / 1289

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Risk Factors
  • Ovarian Neoplasms
  • Odds Ratio
  • Middle Aged
  • Logistic Models
  • Humans
  • Female
  • Epidemiology
 

Citation

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Qin, B., Moorman, P. G., Kelemen, L. E., Alberg, A. J., Barnholtz-Sloan, J. S., Bondy, M., … Bandera, E. V. (2017). Dietary Quality and Ovarian Cancer Risk in African-American Women. Am J Epidemiol, 185(12), 1281–1289. https://doi.org/10.1093/aje/kwx022
Qin, Bo, Patricia G. Moorman, Linda E. Kelemen, Anthony J. Alberg, Jill S. Barnholtz-Sloan, Melissa Bondy, Michele L. Cote, et al. “Dietary Quality and Ovarian Cancer Risk in African-American Women.Am J Epidemiol 185, no. 12 (June 15, 2017): 1281–89. https://doi.org/10.1093/aje/kwx022.
Qin B, Moorman PG, Kelemen LE, Alberg AJ, Barnholtz-Sloan JS, Bondy M, et al. Dietary Quality and Ovarian Cancer Risk in African-American Women. Am J Epidemiol. 2017 Jun 15;185(12):1281–9.
Qin, Bo, et al. “Dietary Quality and Ovarian Cancer Risk in African-American Women.Am J Epidemiol, vol. 185, no. 12, June 2017, pp. 1281–89. Pubmed, doi:10.1093/aje/kwx022.
Qin B, Moorman PG, Kelemen LE, Alberg AJ, Barnholtz-Sloan JS, Bondy M, Cote ML, Funkhouser E, Peters ES, Schwartz AG, Terry P, Schildkraut JM, Bandera EV. Dietary Quality and Ovarian Cancer Risk in African-American Women. Am J Epidemiol. 2017 Jun 15;185(12):1281–1289.
Journal cover image

Published In

Am J Epidemiol

DOI

EISSN

1476-6256

Publication Date

June 15, 2017

Volume

185

Issue

12

Start / End Page

1281 / 1289

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Risk Factors
  • Ovarian Neoplasms
  • Odds Ratio
  • Middle Aged
  • Logistic Models
  • Humans
  • Female
  • Epidemiology