Effects of synaptic noise and filtering on the frequency response of spiking neurons.
Publication
, Journal Article
Brunel, N; Chance, FS; Fourcaud, N; Abbott, LF
Published in: Phys Rev Lett
March 5, 2001
Noise can have a significant impact on the response dynamics of a nonlinear system. For neurons, the primary source of noise comes from background synaptic input activity. If this is approximated as white noise, the amplitude of the modulation of the firing rate in response to an input current oscillating at frequency omega decreases as 1/square root[omega] and lags the input by 45 degrees in phase. However, if filtering due to realistic synaptic dynamics is included, the firing rate is modulated by a finite amount even in the limit omega-->infinity and the phase lag is eliminated. Thus, through its effect on noise inputs, realistic synaptic dynamics can ensure unlagged neuronal responses to high-frequency inputs.
Duke Scholars
Published In
Phys Rev Lett
DOI
ISSN
0031-9007
Publication Date
March 5, 2001
Volume
86
Issue
10
Start / End Page
2186 / 2189
Location
United States
Related Subject Headings
- Synaptic Transmission
- Synapses
- Neurons
- Models, Neurological
- Mathematical Computing
- General Physics
- Action Potentials
- 51 Physical sciences
- 49 Mathematical sciences
- 40 Engineering
Citation
APA
Chicago
ICMJE
MLA
NLM
Brunel, N., Chance, F. S., Fourcaud, N., & Abbott, L. F. (2001). Effects of synaptic noise and filtering on the frequency response of spiking neurons. Phys Rev Lett, 86(10), 2186–2189. https://doi.org/10.1103/PhysRevLett.86.2186
Brunel, N., F. S. Chance, N. Fourcaud, and L. F. Abbott. “Effects of synaptic noise and filtering on the frequency response of spiking neurons.” Phys Rev Lett 86, no. 10 (March 5, 2001): 2186–89. https://doi.org/10.1103/PhysRevLett.86.2186.
Brunel N, Chance FS, Fourcaud N, Abbott LF. Effects of synaptic noise and filtering on the frequency response of spiking neurons. Phys Rev Lett. 2001 Mar 5;86(10):2186–9.
Brunel, N., et al. “Effects of synaptic noise and filtering on the frequency response of spiking neurons.” Phys Rev Lett, vol. 86, no. 10, Mar. 2001, pp. 2186–89. Pubmed, doi:10.1103/PhysRevLett.86.2186.
Brunel N, Chance FS, Fourcaud N, Abbott LF. Effects of synaptic noise and filtering on the frequency response of spiking neurons. Phys Rev Lett. 2001 Mar 5;86(10):2186–2189.
Published In
Phys Rev Lett
DOI
ISSN
0031-9007
Publication Date
March 5, 2001
Volume
86
Issue
10
Start / End Page
2186 / 2189
Location
United States
Related Subject Headings
- Synaptic Transmission
- Synapses
- Neurons
- Models, Neurological
- Mathematical Computing
- General Physics
- Action Potentials
- 51 Physical sciences
- 49 Mathematical sciences
- 40 Engineering