Can attractor network models account for the statistics of firing during persistent activity in prefrontal cortex?
Persistent activity observed in neurophysiological experiments in monkeys is thought to be the neuronal correlate of working memory. Over the last decade, network modellers have strived to reproduce the main features of these experiments. In particular, attractor network models have been proposed in which there is a coexistence between a non-selective attractor state with low background activity with selective attractor states in which sub-groups of neurons fire at rates which are higher (but not much higher) than background rates. A recent detailed statistical analysis of the data seems however to challenge such attractor models: the data indicates that firing during persistent activity is highly irregular (with an average CV larger than 1), while models predict a more regular firing process (CV smaller than 1). We discuss here recent proposals that allow to reproduce this feature of the experiments.
Duke Scholars
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- 5202 Biological psychology
- 3209 Neurosciences
- 1702 Cognitive Sciences
- 1701 Psychology
- 1109 Neurosciences
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- 5202 Biological psychology
- 3209 Neurosciences
- 1702 Cognitive Sciences
- 1701 Psychology
- 1109 Neurosciences