Advancing clinical trial design in pulmonary hypertension
Publication
, Journal Article
Grieve, AP; Chow, SC; Curram, J; Dawe, S; Harnisch, LO; Henig, NR; Hung, HMJ; Ivy, DD; Kawut, SM; Rahbar, MH; Xiao, S; Wilkins, MR
Published in: Pulmonary Circulation
January 1, 2013
In pulmonary hypertension, as in many other diseases, there is a need for a smarter approach to evaluating new treatments. The traditional randomized controlled trial has served medical science well, but constrains the development of treatments for rare diseases. A workshop was established to consider alternative clinical trial designs in pulmonary hypertension and here discusses their merits, limitations and challenges to implementation of novel approaches.
Duke Scholars
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Published In
Pulmonary Circulation
DOI
EISSN
2045-8940
ISSN
2045-8932
Publication Date
January 1, 2013
Volume
3
Issue
1
Start / End Page
217 / 225
Related Subject Headings
- 3201 Cardiovascular medicine and haematology
- 1102 Cardiorespiratory Medicine and Haematology
Citation
APA
Chicago
ICMJE
MLA
NLM
Grieve, A. P., Chow, S. C., Curram, J., Dawe, S., Harnisch, L. O., Henig, N. R., … Wilkins, M. R. (2013). Advancing clinical trial design in pulmonary hypertension. Pulmonary Circulation, 3(1), 217–225. https://doi.org/10.4103/2045-8932.109933
Grieve, A. P., S. C. Chow, J. Curram, S. Dawe, L. O. Harnisch, N. R. Henig, H. M. J. Hung, et al. “Advancing clinical trial design in pulmonary hypertension.” Pulmonary Circulation 3, no. 1 (January 1, 2013): 217–25. https://doi.org/10.4103/2045-8932.109933.
Grieve AP, Chow SC, Curram J, Dawe S, Harnisch LO, Henig NR, et al. Advancing clinical trial design in pulmonary hypertension. Pulmonary Circulation. 2013 Jan 1;3(1):217–25.
Grieve, A. P., et al. “Advancing clinical trial design in pulmonary hypertension.” Pulmonary Circulation, vol. 3, no. 1, Jan. 2013, pp. 217–25. Scopus, doi:10.4103/2045-8932.109933.
Grieve AP, Chow SC, Curram J, Dawe S, Harnisch LO, Henig NR, Hung HMJ, Ivy DD, Kawut SM, Rahbar MH, Xiao S, Wilkins MR. Advancing clinical trial design in pulmonary hypertension. Pulmonary Circulation. 2013 Jan 1;3(1):217–225.
Published In
Pulmonary Circulation
DOI
EISSN
2045-8940
ISSN
2045-8932
Publication Date
January 1, 2013
Volume
3
Issue
1
Start / End Page
217 / 225
Related Subject Headings
- 3201 Cardiovascular medicine and haematology
- 1102 Cardiorespiratory Medicine and Haematology