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Glycerol rhizotomy via a retrosigmoid approach as an alternative treatment for trigeminal neuralgia.

Publication ,  Journal Article
Goodwin, CR; Yang, JX; Bettegowda, C; Hwang, B; James, C; Biser, A; Raza, S; Bender, M; Carson, B; Lee, JYK; Lim, M
Published in: Clin Neurol Neurosurg
December 2013

OBJECTIVES: Trigeminal neuralgia is a sensory nerve disorder characterized by lancinating pain and treated most commonly with carbamazepine, rhizotomy treatment, or open surgical management with microvascular decompression. We describe a novel technique to complement surgical treatment for trigeminal neuralgia via direct injection of the trigeminal nerve with glycerin in the cisternal portion of the nerve. PATIENTS AND METHODS: We performed a retrospective analysis of patients who received standard microvascular decompression and injection of glycerin to the inferior third of the cisternal portion of the nerve anterior to the root entry zone with lack of a compressive vessel on MRI as the primary indication. Fourteen patients were identified and demographic information, post-operative course and complications were recorded. RESULTS: There were eleven females and three males with an average age at time of surgery of 54.8 years. 100% of patients reported that their trigeminal pain was significantly improved following surgical intervention. Four out of fourteen patients reported a 50-80% decrease from the pre-surgery baseline pain at one month and three month follow up. One patient developed a CSF leak, and no surgical site infections or motor deficits were observed. CONCLUSION: Intra-operative glycerin rhizotomy in conjunction with microvascular decompression can be used to safely treat patients suffering from trigeminal neuralgia.

Duke Scholars

Published In

Clin Neurol Neurosurg

DOI

EISSN

1872-6968

Publication Date

December 2013

Volume

115

Issue

12

Start / End Page

2454 / 2456

Location

Netherlands

Related Subject Headings

  • Trigeminal Neuralgia
  • Trigeminal Nerve
  • Rhizotomy
  • Retrospective Studies
  • Neurology & Neurosurgery
  • Middle Aged
  • Microvascular Decompression Surgery
  • Male
  • Magnetic Resonance Imaging
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Goodwin, C. R., Yang, J. X., Bettegowda, C., Hwang, B., James, C., Biser, A., … Lim, M. (2013). Glycerol rhizotomy via a retrosigmoid approach as an alternative treatment for trigeminal neuralgia. Clin Neurol Neurosurg, 115(12), 2454–2456. https://doi.org/10.1016/j.clineuro.2013.09.009
Goodwin, C Rory, Jesse X. Yang, Chetan Bettegowda, Brian Hwang, Carol James, Ann Biser, Shaan Raza, et al. “Glycerol rhizotomy via a retrosigmoid approach as an alternative treatment for trigeminal neuralgia.Clin Neurol Neurosurg 115, no. 12 (December 2013): 2454–56. https://doi.org/10.1016/j.clineuro.2013.09.009.
Goodwin CR, Yang JX, Bettegowda C, Hwang B, James C, Biser A, et al. Glycerol rhizotomy via a retrosigmoid approach as an alternative treatment for trigeminal neuralgia. Clin Neurol Neurosurg. 2013 Dec;115(12):2454–6.
Goodwin, C. Rory, et al. “Glycerol rhizotomy via a retrosigmoid approach as an alternative treatment for trigeminal neuralgia.Clin Neurol Neurosurg, vol. 115, no. 12, Dec. 2013, pp. 2454–56. Pubmed, doi:10.1016/j.clineuro.2013.09.009.
Goodwin CR, Yang JX, Bettegowda C, Hwang B, James C, Biser A, Raza S, Bender M, Carson B, Lee JYK, Lim M. Glycerol rhizotomy via a retrosigmoid approach as an alternative treatment for trigeminal neuralgia. Clin Neurol Neurosurg. 2013 Dec;115(12):2454–2456.

Published In

Clin Neurol Neurosurg

DOI

EISSN

1872-6968

Publication Date

December 2013

Volume

115

Issue

12

Start / End Page

2454 / 2456

Location

Netherlands

Related Subject Headings

  • Trigeminal Neuralgia
  • Trigeminal Nerve
  • Rhizotomy
  • Retrospective Studies
  • Neurology & Neurosurgery
  • Middle Aged
  • Microvascular Decompression Surgery
  • Male
  • Magnetic Resonance Imaging
  • Humans