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Optimal visual perception and detection of oral cavity neoplasia.

Publication ,  Journal Article
Utzinger, U; Bueeler, M; Oh, S; Heintzelman, DL; Svistun, ES; Abd-El-Barr, M; Gillenwater, A; Richards-Kortum, R
Published in: IEEE Trans Biomed Eng
March 2003

The most common way to detect disease is by visual inspection of the suspect tissue. However, the human eye is not optimized for this task because the perceived spectrum of light is divided into three channels, all of which have overlapping spectral sensitivity curves. Here, we present new methods to optimize visually perceived contrast based on spectral differences between normal and abnormal tissue. We apply these methods to the perception of fluorescence emission from the oral cavity. Abnormalities in the oral cavity are optimally perceived when the excitation is between nm. To optimally visualize fluorescence at 340-nm excitation, the emission should be observed through a blue bandpass filter transmitting light at 430 nm.

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Published In

IEEE Trans Biomed Eng

DOI

ISSN

0018-9294

Publication Date

March 2003

Volume

50

Issue

3

Start / End Page

396 / 399

Location

United States

Related Subject Headings

  • Visual Perception
  • Spectrometry, Fluorescence
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Reference Values
  • Quality Control
  • Precancerous Conditions
  • Physical Examination
  • Observer Variation
  • Mouth Neoplasms
 

Citation

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Utzinger, U., Bueeler, M., Oh, S., Heintzelman, D. L., Svistun, E. S., Abd-El-Barr, M., … Richards-Kortum, R. (2003). Optimal visual perception and detection of oral cavity neoplasia. IEEE Trans Biomed Eng, 50(3), 396–399. https://doi.org/10.1109/TBME.2003.808832
Utzinger, Urs, Michael Bueeler, Sanghoon Oh, Douglas L. Heintzelman, Ekaterina S. Svistun, Muhammad Abd-El-Barr, Ann Gillenwater, and Rebecca Richards-Kortum. “Optimal visual perception and detection of oral cavity neoplasia.IEEE Trans Biomed Eng 50, no. 3 (March 2003): 396–99. https://doi.org/10.1109/TBME.2003.808832.
Utzinger U, Bueeler M, Oh S, Heintzelman DL, Svistun ES, Abd-El-Barr M, et al. Optimal visual perception and detection of oral cavity neoplasia. IEEE Trans Biomed Eng. 2003 Mar;50(3):396–9.
Utzinger, Urs, et al. “Optimal visual perception and detection of oral cavity neoplasia.IEEE Trans Biomed Eng, vol. 50, no. 3, Mar. 2003, pp. 396–99. Pubmed, doi:10.1109/TBME.2003.808832.
Utzinger U, Bueeler M, Oh S, Heintzelman DL, Svistun ES, Abd-El-Barr M, Gillenwater A, Richards-Kortum R. Optimal visual perception and detection of oral cavity neoplasia. IEEE Trans Biomed Eng. 2003 Mar;50(3):396–399.

Published In

IEEE Trans Biomed Eng

DOI

ISSN

0018-9294

Publication Date

March 2003

Volume

50

Issue

3

Start / End Page

396 / 399

Location

United States

Related Subject Headings

  • Visual Perception
  • Spectrometry, Fluorescence
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Reference Values
  • Quality Control
  • Precancerous Conditions
  • Physical Examination
  • Observer Variation
  • Mouth Neoplasms