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Optical sectioning wide-field microscopy for imaging oral cancer

Publication ,  Conference
Abd-El-Barr, MM; Hsu, ER; Anslyn, EV; Descour, MR; Lotan, R; Gillenwater, AM; Richards-Kortum, RR
Published in: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
December 1, 2002

We describe the use of an optical sectioning wide-field microscope with an exogenous dye in order to improve the visualization of early oral cancer detection. We show positive results in imaging and optically sectioning turbid tissue phantoms stained with Acridine Orange, a non-specific fluorescent DNA dye. This optical technique, if coupled with appropriate contrast agents could improve both the visualization and specificity of epithelial cancer detection.

Duke Scholars

Published In

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ISSN

0589-1019

Publication Date

December 1, 2002

Volume

3

Start / End Page

2306 / 2307
 

Citation

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Abd-El-Barr, M. M., Hsu, E. R., Anslyn, E. V., Descour, M. R., Lotan, R., Gillenwater, A. M., & Richards-Kortum, R. R. (2002). Optical sectioning wide-field microscopy for imaging oral cancer. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 3, pp. 2306–2307).
Abd-El-Barr, M. M., E. R. Hsu, E. V. Anslyn, M. R. Descour, R. Lotan, A. M. Gillenwater, and R. R. Richards-Kortum. “Optical sectioning wide-field microscopy for imaging oral cancer.” In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 3:2306–7, 2002.
Abd-El-Barr MM, Hsu ER, Anslyn EV, Descour MR, Lotan R, Gillenwater AM, et al. Optical sectioning wide-field microscopy for imaging oral cancer. In: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2002. p. 2306–7.
Abd-El-Barr, M. M., et al. “Optical sectioning wide-field microscopy for imaging oral cancer.” Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol. 3, 2002, pp. 2306–07.
Abd-El-Barr MM, Hsu ER, Anslyn EV, Descour MR, Lotan R, Gillenwater AM, Richards-Kortum RR. Optical sectioning wide-field microscopy for imaging oral cancer. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2002. p. 2306–2307.

Published In

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ISSN

0589-1019

Publication Date

December 1, 2002

Volume

3

Start / End Page

2306 / 2307