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Factors Associated with Life Expectancy in Patients with Metastatic Spine Disease from Adenocarcinoma of the Lung

Publication ,  Journal Article
Goodwin, CR; Khattab, MH; Sankey, EW; Elder, BD; Kosztowski, TA; Sarabia-Estrada, R; Bydon, A; Witham, TF; Wolinsky, JP; Gokaslan, ZL; Sciubba, DM
Published in: Global Spine Journal
January 7, 2015

Study Design Retrospective study. Objective Our objective was to identify preoperative prognostic factors associated with survival in patients with spinal metastasis from lung carcinoma. Methods A retrospective analysis of 26 patients diagnosed with lung carcinoma metastatic to the spinal column was performed to determine factors associated with survival. We used 3 months survival as the clinical cutoff for whether surgical intervention should be performed. We analyzed patients who survived less than 3 months compared with those who survived more than 3 months. Demographic, preoperative, operative, and postoperative factors including functional scores were collected for analysis. Results The median survival for all patients in our study was 3.5 months. We found a statistically significant difference between the group that survived less than 3 months and the group that survived greater than 3 months in terms of extrathoracic metastasis, visceral metastasis, and average postoperative modified Rankin score. Conclusion Determining which patients with lung cancer spinal metastases will benefit from surgical intervention is often dictated by the patient's predicted life expectancy. Factors associated with poorer prognosis include age, functional status, visceral metastases, and extrathoracic metastases. Although the prognosis for patients with lung cancer spinal metastases is poor, some patients may experience long-term benefit from surgical intervention.

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Published In

Global Spine Journal

DOI

EISSN

2192-5690

ISSN

2192-5682

Publication Date

January 7, 2015

Volume

5

Issue

5

Start / End Page

417 / 424

Related Subject Headings

  • 3202 Clinical sciences
 

Citation

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Chicago
ICMJE
MLA
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Goodwin, C. R., Khattab, M. H., Sankey, E. W., Elder, B. D., Kosztowski, T. A., Sarabia-Estrada, R., … Sciubba, D. M. (2015). Factors Associated with Life Expectancy in Patients with Metastatic Spine Disease from Adenocarcinoma of the Lung. Global Spine Journal, 5(5), 417–424. https://doi.org/10.1055/s-0035-1554778
Goodwin, C. R., M. H. Khattab, E. W. Sankey, B. D. Elder, T. A. Kosztowski, R. Sarabia-Estrada, A. Bydon, et al. “Factors Associated with Life Expectancy in Patients with Metastatic Spine Disease from Adenocarcinoma of the Lung.” Global Spine Journal 5, no. 5 (January 7, 2015): 417–24. https://doi.org/10.1055/s-0035-1554778.
Goodwin CR, Khattab MH, Sankey EW, Elder BD, Kosztowski TA, Sarabia-Estrada R, et al. Factors Associated with Life Expectancy in Patients with Metastatic Spine Disease from Adenocarcinoma of the Lung. Global Spine Journal. 2015 Jan 7;5(5):417–24.
Goodwin, C. R., et al. “Factors Associated with Life Expectancy in Patients with Metastatic Spine Disease from Adenocarcinoma of the Lung.” Global Spine Journal, vol. 5, no. 5, Jan. 2015, pp. 417–24. Scopus, doi:10.1055/s-0035-1554778.
Goodwin CR, Khattab MH, Sankey EW, Elder BD, Kosztowski TA, Sarabia-Estrada R, Bydon A, Witham TF, Wolinsky JP, Gokaslan ZL, Sciubba DM. Factors Associated with Life Expectancy in Patients with Metastatic Spine Disease from Adenocarcinoma of the Lung. Global Spine Journal. 2015 Jan 7;5(5):417–424.
Journal cover image

Published In

Global Spine Journal

DOI

EISSN

2192-5690

ISSN

2192-5682

Publication Date

January 7, 2015

Volume

5

Issue

5

Start / End Page

417 / 424

Related Subject Headings

  • 3202 Clinical sciences