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Ocular toxoplasmosis presenting with focal retinal nerve fiber atrophy simulating glaucoma.

Publication ,  Journal Article
Sheets, CW; Grewal, DS; Greenfield, DS
Published in: J Glaucoma
February 2009

PURPOSE: We describe a patient with ocular hypertension and nonglaucomatous retinal nerve fiber layer (RNFL) atrophy associated with an ocular toxoplasmosis retinal lesion. PATIENT AND METHOD: Single case report. RESULTS: An RNFL defect was identified adjacent to a circumscribed pigmented chorioretinal lesion superior to the macular region. The optic disc showed a prominent central cup without focal neural rim atrophy. Red-free photography and RNFL imaging using optical coherence tomography and scanning laser polarimetry showed corresponding focal RNFL atrophy. The toxoplasmosis lesion was characterized by an apparent full thickness disruption in retinal architecture, including the retinal ganglion cell layer, using spectral-domain optical coherence tomography. CONCLUSIONS: Nonglaucomatous retinal lesions may simulate glaucomatous RNFL atrophy and visual field loss, particularly when focal damage to the retinal ganglion cells occurs. Careful inspection of the retina and optic disc, with attention to the integrity of the neural rim, and analysis of the pattern of RNFL loss in proximity to a retinal lesion may enable the clinician to differentiate glaucomatous and nonglaucomatous pathogenic mechanisms.

Duke Scholars

Published In

J Glaucoma

DOI

EISSN

1536-481X

Publication Date

February 2009

Volume

18

Issue

2

Start / End Page

129 / 131

Location

United States

Related Subject Headings

  • Toxoplasmosis, Ocular
  • Tomography, Optical Coherence
  • Retinal Ganglion Cells
  • Retinal Diseases
  • Optic Nerve
  • Ophthalmology & Optometry
  • Nerve Fibers
  • Humans
  • Glaucoma
  • Follow-Up Studies
 

Citation

APA
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ICMJE
MLA
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Sheets, C. W., Grewal, D. S., & Greenfield, D. S. (2009). Ocular toxoplasmosis presenting with focal retinal nerve fiber atrophy simulating glaucoma. J Glaucoma, 18(2), 129–131. https://doi.org/10.1097/IJG.0b013e318179f83f
Sheets, Clinton W., Dilraj S. Grewal, and David S. Greenfield. “Ocular toxoplasmosis presenting with focal retinal nerve fiber atrophy simulating glaucoma.J Glaucoma 18, no. 2 (February 2009): 129–31. https://doi.org/10.1097/IJG.0b013e318179f83f.
Sheets CW, Grewal DS, Greenfield DS. Ocular toxoplasmosis presenting with focal retinal nerve fiber atrophy simulating glaucoma. J Glaucoma. 2009 Feb;18(2):129–31.
Sheets, Clinton W., et al. “Ocular toxoplasmosis presenting with focal retinal nerve fiber atrophy simulating glaucoma.J Glaucoma, vol. 18, no. 2, Feb. 2009, pp. 129–31. Pubmed, doi:10.1097/IJG.0b013e318179f83f.
Sheets CW, Grewal DS, Greenfield DS. Ocular toxoplasmosis presenting with focal retinal nerve fiber atrophy simulating glaucoma. J Glaucoma. 2009 Feb;18(2):129–131.

Published In

J Glaucoma

DOI

EISSN

1536-481X

Publication Date

February 2009

Volume

18

Issue

2

Start / End Page

129 / 131

Location

United States

Related Subject Headings

  • Toxoplasmosis, Ocular
  • Tomography, Optical Coherence
  • Retinal Ganglion Cells
  • Retinal Diseases
  • Optic Nerve
  • Ophthalmology & Optometry
  • Nerve Fibers
  • Humans
  • Glaucoma
  • Follow-Up Studies