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Patient-reported symptoms and quality of life 
in adults with acute leukemia: a systematic review.

Publication ,  Journal Article
Leak Bryant, A; Lee Walton, A; Shaw-Kokot, J; Mayer, DK; Reeve, BB
Published in: Oncol Nurs Forum
March 2015

PURPOSE/OBJECTIVES: Systematically summarize findings from research conducted on adult acute leukemia survivors as they relate to symptoms and quality of life (QOL). 
 DATA SOURCES: Systematic review of the literature from 1990–2013 found in the PubMed, PsycINFO®, EMBASE, and CINAHL® databases, as well as manual searches. 
 DATA SYNTHESIS: The review identified 16 quantitative studies and 1 qualitative study published from 1990–2013 that used a self-reported QOL or symptom questionnaire. Fatigue was the most commonly assessed and reported symptom, followed by depression. 
 CONCLUSIONS: Acute leukemia and its treatment have a significant impact in all QOL domains. Future studies should include longitudinal research, more than one recruitment site, increased minority representation, and home-based exercise interventions as ways to improve all domains of QOL. 
 IMPLICATIONS FOR NURSING: This review increases awareness of commonly reported symptoms faced by adults with acute leukemia. Oncology nurses are central in monitoring and reporting symptoms to the interdisciplinary team that may contribute to changes in function, with the overall goal of optimizing QOL over time.

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Published In

Oncol Nurs Forum

DOI

EISSN

1538-0688

Publication Date

March 2015

Volume

42

Issue

2

Start / End Page

E91 / E101

Location

United States

Related Subject Headings

  • Symptom Assessment
  • Survivors
  • Spirituality
  • Research Design
  • Quality of Life
  • Qualitative Research
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Nursing
  • Middle Aged
  • Leukemia, Myeloid, Acute
 

Citation

APA
Chicago
ICMJE
MLA
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Leak Bryant, A., Lee Walton, A., Shaw-Kokot, J., Mayer, D. K., & Reeve, B. B. (2015). Patient-reported symptoms and quality of life 
in adults with acute leukemia: a systematic review. Oncol Nurs Forum, 42(2), E91–E101. https://doi.org/10.1188/15.ONF.E91-E101
Leak Bryant, Ashley, AnnMarie Lee Walton, Julia Shaw-Kokot, Deborah K. Mayer, and Bryce B. Reeve. “Patient-reported symptoms and quality of life 
in adults with acute leukemia: a systematic review.Oncol Nurs Forum 42, no. 2 (March 2015): E91–101. https://doi.org/10.1188/15.ONF.E91-E101.
Leak Bryant A, Lee Walton A, Shaw-Kokot J, Mayer DK, Reeve BB. Patient-reported symptoms and quality of life 
in adults with acute leukemia: a systematic review. Oncol Nurs Forum. 2015 Mar;42(2):E91–101.
Leak Bryant, Ashley, et al. “Patient-reported symptoms and quality of life 
in adults with acute leukemia: a systematic review.Oncol Nurs Forum, vol. 42, no. 2, Mar. 2015, pp. E91–101. Pubmed, doi:10.1188/15.ONF.E91-E101.
Leak Bryant A, Lee Walton A, Shaw-Kokot J, Mayer DK, Reeve BB. Patient-reported symptoms and quality of life 
in adults with acute leukemia: a systematic review. Oncol Nurs Forum. 2015 Mar;42(2):E91–E101.

Published In

Oncol Nurs Forum

DOI

EISSN

1538-0688

Publication Date

March 2015

Volume

42

Issue

2

Start / End Page

E91 / E101

Location

United States

Related Subject Headings

  • Symptom Assessment
  • Survivors
  • Spirituality
  • Research Design
  • Quality of Life
  • Qualitative Research
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Nursing
  • Middle Aged
  • Leukemia, Myeloid, Acute