Skip to main content
Journal cover image

Metabolomics of Diabetic Retinopathy.

Publication ,  Journal Article
Liew, G; Lei, Z; Tan, G; Joachim, N; Ho, I-V; Wong, TY; Mitchell, P; Gopinath, B; Crossett, B
Published in: Curr Diab Rep
September 23, 2017

PURPOSE OF REVIEW: Metabolomics is the study of dysregulated metabolites in biological materials. We reviewed the use of the technique to elucidate the genetic and environmental factors that contribute to the development of diabetic retinopathy. RECENT FINDINGS: With regard to metabolomic studies of diabetic retinopathy, the field remains in its infancy with few studies published to date and little replication of results. Vitreous and serum samples are the main tissues examined, and dysregulation in pathways such as the pentose phosphate pathway, arginine to proline pathway, polyol pathway, and ascorbic acidic pathways have been reported. Few studies have examined the metabolomic underpinnings of diabetic retinopathy. Further research is required to replicate findings to date and determine longitudinal associations with disease.

Duke Scholars

Published In

Curr Diab Rep

DOI

EISSN

1539-0829

Publication Date

September 23, 2017

Volume

17

Issue

11

Start / End Page

102

Location

United States

Related Subject Headings

  • Vitreous Body
  • Metabolomics
  • Humans
  • Endocrinology & Metabolism
  • Diabetic Retinopathy
  • Diabetes Mellitus
  • Biomarkers
  • 3210 Nutrition and dietetics
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Liew, G., Lei, Z., Tan, G., Joachim, N., Ho, I.-V., Wong, T. Y., … Crossett, B. (2017). Metabolomics of Diabetic Retinopathy. Curr Diab Rep, 17(11), 102. https://doi.org/10.1007/s11892-017-0939-3
Liew, Gerald, Zhou Lei, Gavin Tan, Nichole Joachim, I-Van Ho, Tien Y. Wong, Paul Mitchell, Bamini Gopinath, and Ben Crossett. “Metabolomics of Diabetic Retinopathy.Curr Diab Rep 17, no. 11 (September 23, 2017): 102. https://doi.org/10.1007/s11892-017-0939-3.
Liew G, Lei Z, Tan G, Joachim N, Ho I-V, Wong TY, et al. Metabolomics of Diabetic Retinopathy. Curr Diab Rep. 2017 Sep 23;17(11):102.
Liew, Gerald, et al. “Metabolomics of Diabetic Retinopathy.Curr Diab Rep, vol. 17, no. 11, Sept. 2017, p. 102. Pubmed, doi:10.1007/s11892-017-0939-3.
Liew G, Lei Z, Tan G, Joachim N, Ho I-V, Wong TY, Mitchell P, Gopinath B, Crossett B. Metabolomics of Diabetic Retinopathy. Curr Diab Rep. 2017 Sep 23;17(11):102.
Journal cover image

Published In

Curr Diab Rep

DOI

EISSN

1539-0829

Publication Date

September 23, 2017

Volume

17

Issue

11

Start / End Page

102

Location

United States

Related Subject Headings

  • Vitreous Body
  • Metabolomics
  • Humans
  • Endocrinology & Metabolism
  • Diabetic Retinopathy
  • Diabetes Mellitus
  • Biomarkers
  • 3210 Nutrition and dietetics
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services